DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9676 and Tmprss2

DIOPT Version :9

Sequence 1:	NP_728008.1	Gene:	CG9676 / 32647	FlyBaseID:	FBgn0030773	Length:	251	Species:	Drosophila melanogaster
Sequence 2:	XP_008766769.1	Gene:	Tmprss2 / 156435	RGDID:	620766	Length:	580	Species:	Rattus norvegicus

Alignment Length:	240	Identity:	81/240 - (33%)
Similarity:	121/240 - (50%)	Gaps:	21/240 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 EPRIVGGTKAREGQFPHQISLRRRGSHTCGGSIISKDYVVTAAHCVKQGNNVAPANELEIQAGSL 89
            :.|||||:.|..|.:|.|:||..:|.|.||||||:.:::|||||||::  .::........||.|
  Rat   251 QSRIVGGSTASPGDWPWQVSLHVQGIHVCGGSIITPEWIVTAAHCVEE--PLSSPRYWTAFAGIL 313

  Fly    90 --LLSSGGVRVPVATVTVHPNYNS--NGHDVAVLRLRNSLTFNSNIAAIKLATEDPPNDATVD-- 148
              .|...|.|..|..|..||||:|  ..:|:|:::|:..|.||..:..:.|.......|...:
  Rat   314 KQSLMFYGSRHQVEKVISHPNYDSKTKNNDIALMKLQTPLAFNDVVKPVCLPNPGMMLDLAQECW 378

  Fly   149 ISGWGAISQRGPISNSLLYVQVKALSRESCQKTYL--RQLPETTMC---LLHPKDKGACYGDSGG 208
            ||||||..::|..|:.|....|..:....|...|:  ..:....:|   |....|  :|.|||||
  Rat   379 ISGWGATYEKGKTSDVLNAAMVPLIEPSKCNSKYIYNNLITPAMICAGFLQGSVD--SCQGDSGG 441

  Fly   209 P-ATYQGK---LVGLASFVIGGCGRA-APDGYERVSKLRNWIAEK 248
            | .|.:.:   |:|..|:. .||.:| .|..|..|:...:||.::
  Rat   442 PLVTLKNEIWWLIGDTSWG-SGCAKAYRPGVYGNVTVFTDWIYQQ 485

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9676	NP_728008.1	Tryp_SPc	27..245	CDD:214473	79/233 (34%)
CG9676	NP_728008.1	Tryp_SPc	28..248	CDD:238113	80/235 (34%)
Tmprss2	XP_008766769.1	LDLa	112..147	CDD:238060
		SRCR_2	152..247	CDD:292133
		Tryp_SPc	253..482	CDD:214473	79/233 (34%)
		Tryp_SPc	254..485	CDD:238113	80/235 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910