DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9676 and tmprss2.15

DIOPT Version :9

Sequence 1:	NP_728008.1	Gene:	CG9676 / 32647	FlyBaseID:	FBgn0030773	Length:	251	Species:	Drosophila melanogaster
Sequence 2:	XP_031752206.1	Gene:	tmprss2.15 / 101732233	XenbaseID:	XB-GENE-22065943	Length:	504	Species:	Xenopus tropicalis

Alignment Length:	261	Identity:	91/261 - (34%)
Similarity:	127/261 - (48%)	Gaps:	34/261 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 CAAGVLAQNDSV-------VEPRIVGGTKAREGQFPHQISLRR---RGSHTCGGSIISKDYVVTA 66
            ||:|.:.....:       |:.||||||.|..|.:|.|:.|.:   ...:.||||||:..::|||
Frog   242 CASGNMVSLRCISCGLSTKVDSRIVGGTPASVGDWPWQVELLKLVGTSIYLCGGSIITPHWIVTA 306

  Fly    67 AHCVKQGNNVAPANELEIQAGSLLLS---SGGVRVPVATVTVHPNYNS--NGHDVAVLRLRNSLT 126
            |||| .|:...| :..::.||||.:.   |.|..|..|  .|||:|:|  ..:|||:|:|..:|.
Frog   307 AHCV-YGSTSTP-SAFKVFAGSLTIQSYYSAGYTVERA--LVHPSYSSYTQIYDVALLKLTAALV 367

  Fly   127 FNSNIAAIKLATEDPP--NDATVDISGWGAISQRGPISNSLLYVQVKALSRESCQK--TYLRQLP 187
            |.:|:..:.|.....|  ......|||||..::.|.||.:|:...|..:|..:|.:  .|...:.
Frog   368 FTTNLRPVCLPNVGMPWAEGQPCWISGWGTTAEGGSISKNLMAASVPIISSTTCNQAAVYGGAIS 432

  Fly   188 ETTMC---LLHPKDKGACYGDSGGPATYQGK----LVGLASFVIGGCGRA-APDGYERVSKLRNW 244
            .|.||   |....|  .|.||||||...:..    |||..|:.. ||.|| .|..|..|:....|
Frog   433 STMMCAGYLSGGTD--TCQGDSGGPLVTKTNSLWWLVGDTSWGY-GCARAYKPGVYGNVTVFIEW 494

  Fly   245 I 245
            |
Frog   495 I 495

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9676	NP_728008.1	Tryp_SPc	27..245	CDD:214473	85/237 (36%)
CG9676	NP_728008.1	Tryp_SPc	28..248	CDD:238113	86/238 (36%)
tmprss2.15	XP_031752206.1	LDLa	93..121	CDD:238060
		SRCR_2	164..259	CDD:406055	3/16 (19%)
		Tryp_SPc	265..498	CDD:238113	86/238 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910