DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9676 and f12

DIOPT Version :9

Sequence 1:	NP_728008.1	Gene:	CG9676 / 32647	FlyBaseID:	FBgn0030773	Length:	251	Species:	Drosophila melanogaster
Sequence 2:	XP_017947702.2	Gene:	f12 / 100493769	XenbaseID:	XB-GENE-1004811	Length:	597	Species:	Xenopus tropicalis

Alignment Length:	251	Identity:	69/251 - (27%)
Similarity:	109/251 - (43%)	Gaps:	22/251 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 QNDSVVEPRIVGGTKAREGQFPHQISLRRRGSHTCGGSIISKDYVVTAAHCVKQGNNVAPANELE 83
            |....:.||||||..|.....|: |:.....:|.||||:||..::||||||:.|..||...:.:.
Frog   350 QKTPSIMPRIVGGLVALPASHPY-IAALYIDNHFCGGSLISPCWIVTAAHCLDQRPNVTKISVVL 413

  Fly    84 IQAGSLLLSSGGVRVPVATVTVHPNY--NSNGHDVAVLRLR--NSL---TFNSNIAAIKLATEDP 141
            .|:.........|.:.|....:|..|  ::..||:|:::::  |.|   .|:..:..|.|..:..
Frog   414 GQSRFNTTDQHTVTLLVEKYILHEKYYGDTLQHDIALVKVKSINGLCASEFSQFVQPICLPQQFK 478

  Fly   142 PNDATVD--ISGWGAISQRGPISNSLLYVQ---VKALSRESCQKTYL---RQLPETTMCLLHPKD 198
            ..::|..  ::|||  .|.....:...::|   :..:....||...:   |.||...........
Frog   479 MAESTKQCVVAGWG--HQYEGAEHYAFFLQEASMPIIPYTQCQSPSVHGDRMLPGMLCAGFMEGG 541

  Fly   199 KGACYGDSGGPATYQ--GK--LVGLASFVIGGCGRAAPDGYERVSKLRNWIAEKAS 250
            ..||.||||||...:  |:  |.|:.|:..|......|..|..|:...:||....|
Frog   542 VDACQGDSGGPLVCEVDGRIELHGVVSWGSGCAEENKPGVYTAVTSYTDWIRANIS 597

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9676	NP_728008.1	Tryp_SPc	27..245	CDD:214473	64/236 (27%)
CG9676	NP_728008.1	Tryp_SPc	28..248	CDD:238113	65/238 (27%)
f12	XP_017947702.2	fn2	46..87	CDD:394995
		EGF_CA	95..129	CDD:238011
		KR	213..298	CDD:214527
		Tryp_SPc	359..595	CDD:238113	65/238 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910