Protein Alignment Sep4 and CDC3

DIOPT Version :9

• Sequence 1: NP_573147.2
• Gene: Sep4 / 32646
• FlyBaseID: FBgn0259923
• Length: 427
• Species: Drosophila melanogaster
• Sequence 2: NP_013418.2
• Gene: CDC3 / 851024
• SGDID: S000004306
• Length: 520
• Species: Saccharomyces cerevisiae
• Alignment Length: 401
• Identity: 139/401 - (34%)
• Similarity: 224/401 - (55%)
• Gaps: 52/401 - (12%)

  Fly    65 YIGFATLPEQVHRKSVKRGFEFTLMVVGESGLGKSTLINSLFLGDLYKNRQMPNVEERI------ 123
            |:|||.||:|.||:|:|.||.|.|:.||..|:||:||:.:||..|..:...:.:.||.:
Yeast    99 YVGFANLPKQWHRRSIKNGFSFNLLCVGPDGIGKTTLMKTLFNNDDIEANLVKDYEEELANDQEE 163

  Fly   124 -------------EKTTKVEKKTMD--IEERGVRLRLTVVDTPGFGDAINCED-SWRVCTQYIDE 172
                         |:..||:.|:.:  |||.||:|.|.|:||.||||.:|.:. ||....:.||.
Yeast   164 EEGQGEGHENQSQEQRHKVKIKSYESVIEENGVKLNLNVIDTEGFGDFLNNDQKSWDPIIKEIDS 228

  Fly   173 QFRQYFTDESGLNRRNIQDNRVHCCLYFVPPWGHSLRQMDLDLIRRLHRKVNIVLVIGKADCLNK 237
            :|.||...|:.:||.:|.|.|:|.||||:.|.||.|:.:||..::.::.|.|::.||.|:|.|..
Yeast   229 RFDQYLDAENKINRHSINDKRIHACLYFIEPTGHYLKPLDLKFMQSVYEKCNLIPVIAKSDILTD 293

  Fly   238 QEVRKLKERILQDLEDNHIQLYQFPECDSDEDDDFKQQDRELKASIPFAVVGSNTILE-VAGKKV 301
            :|:...|:.|:..|..::|:|:: |...|::|.:.......|.:|:|:||:|||.|:| .:|.:|
Yeast   294 EEILSFKKTIMNQLIQSNIELFK-PPIYSNDDAENSHLSERLFSSLPYAVIGSNDIVENYSGNQV 357

  Fly   302 RGRQYPWGVVNVEDPEHSDFIKLRTFLISTHMQDLKDTTQDVHYENFRAQCISQI---------- 356
            |||.|||||:.|::..||||..|:..||...|::||:.|..:.|||:|:..::::
Yeast   358 RGRSYPWGVIEVDNDNHSDFNLLKNLLIKQFMEELKERTSKILYENYRSSKLAKLGIKQDNSVFK 422

  Fly   357 ---------SQHALRERGKLKRDSISSTNGFDAAISETDRLLLQKDEEI----RRMQDMLTQ--- 405
                     .:..|.| .||.:..|.....|...:||.::.|.:.:.|:    :.|::.||:
Yeast   423 EFDPISKQQEEKTLHE-AKLAKLEIEMKTVFQQKVSEKEKKLQKSETELFARHKEMKEKLTKQLK 486

  Fly   406 -MQEKLKQTHL 415
             :::|.||..|
Yeast   487 ALEDKKKQLEL 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sep4	NP_573147.2	CDC3	65..420	CDD:227352	139/401 (35%)
		CDC_Septin	82..357	CDD:206649	111/316 (35%)
CDC3	NP_013418.2	CDC3	97..503	CDD:227352	139/401 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5019
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG51878
OrthoFinder	1	1.000	-	-		FOG0000103
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18884
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2060
SonicParanoid	1	1.000	-	-		X204
TreeFam	0	0.000	Not matched by this tool.
	7	6.950