Protein Alignment Sep4 and Septin2

DIOPT Version :9

• Sequence 1: NP_573147.2
• Gene: Sep4 / 32646
• FlyBaseID: FBgn0259923
• Length: 427
• Species: Drosophila melanogaster
• Sequence 2: XP_006529303.1
• Gene: Septin2 / 18000
• MGIID: 97298
• Length: 391
• Species: Mus musculus
• Alignment Length: 391
• Identity: 213/391 - (54%)
• Similarity: 285/391 - (72%)
• Gaps: 33/391 - (8%)

  Fly    35 GSSSSGIEAVKCRPPIYPKPKTPSFDKDRDYIGFATLPEQVHRKSVKRGFEFTLMVVGESGLGKS 99
            |.:....:..|.:|..:..|:||.      |:|||.||.||||||||:|||||||||||||||||
Mouse    23 GQTGKSRKMSKQQPTQFINPETPG------YVGFANLPNQVHRKSVKKGFEFTLMVVGESGLGKS 81

  Fly   100 TLINSLFLGDLYKNRQMPNVEERIEKTTKVEKKTMDIEERGVRLRLTVVDTPGFGDAINCEDSWR 164
            ||||||||.|||..|.:|...|:||:|.::|..|::||||||:||||||||||:||||||.|.::
Mouse    82 TLINSLFLTDLYPERIIPGAAEKIERTVQIEASTVEIEERGVKLRLTVVDTPGYGDAINCRDCFK 146

  Fly   165 VCTQYIDEQFRQYFTDESGLNRRNIQDNRVHCCLYFVPPWGHSLRQMDLDLIRRLHRKVNIVLVI 229
            ....||||||.:|..||||||||:|.|||||||.||:.|:||.|:.:|:..::.:|.|||||.||
Mouse   147 TIISYIDEQFERYLHDESGLNRRHIIDNRVHCCFYFISPFGHGLKPLDVAFMKAIHNKVNIVPVI 211

  Fly   230 GKADCLNKQEVRKLKERILQDLEDNHIQLYQFPECDSDEDDDFKQQDRELKASIPFAVVGSNTIL 294
            .|||.|..:|..:||:|||.::|::.|::|..|:.:||||:|||:|.|.|||||||:|||||.::
Mouse   212 AKADTLTLKERERLKKRILDEIEEHSIKIYHLPDAESDEDEDFKEQTRLLKASIPFSVVGSNQLI 276

  Fly   295 EVAGKKVRGRQYPWGVVNVEDPEHSDFIKLRTFLISTHMQDLKDTTQDVHYENFRAQCISQISQH 359
            |..|||||||.||||||.||:|||:||:||||.|| ||||||::.|||:||||||::.:
Mouse   277 EAKGKKVRGRLYPWGVVEVENPEHNDFLKLRTMLI-THMQDLQEVTQDLHYENFRSERL------ 334

  Fly   360 ALRERG--KLKRDSISSTNGFDAAISETDRLLLQKDEEIRRMQDMLTQMQEKLKQTHLMEMKKND 422
               :||  |::.:.::.           |::||:|:.|:||||:|:.:||.:::    |:|:..|
Mouse   335 ---KRGGRKVENEDMNK-----------DQILLEKEAELRRMQEMIARMQAQMQ----MQMQGGD 381

  Fly   423 S 423
            |
Mouse   382 S 382

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sep4	NP_573147.2	CDC3	65..420	CDD:227352	205/356 (58%)
		CDC_Septin	82..357	CDD:206649	174/274 (64%)
Septin2	XP_006529303.1	Septin	64..343	CDD:366275	177/288 (61%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5019
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S763
OMA	1	1.010	-	-		QHG51878
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000103
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2060
SonicParanoid	1	1.000	-	-		X204
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.800