Protein Alignment Sep4 and unc-61

DIOPT Version :9

• Sequence 1: NP_573147.2
• Gene: Sep4 / 32646
• FlyBaseID: FBgn0259923
• Length: 427
• Species: Drosophila melanogaster
• Sequence 2: NP_872156.2
• Gene: unc-61 / 179976
• WormBaseID: WBGene00006795
• Length: 530
• Species: Caenorhabditis elegans
• Alignment Length: 461
• Identity: 150/461 - (32%)
• Similarity: 241/461 - (52%)
• Gaps: 65/461 - (14%)

  Fly     2 KHQP---PPPPLP---LSQPPTMGATAAGGVASVISTMNGSSSSGIEAVKCRPPIYPKP-KTPSF 59
            ||.|   ||||:|   .:||.....|......|.|:|...|....|.|     |..|.| |:.|.
 Worm    78 KHLPPHQPPPPVPHHHQNQPTHNNTTTISSATSSINTTTTSKKPTIAA-----PTAPSPIKSLSD 137

  Fly    60 DKDR-----DYIGFATLPEQVHRKSVKRGFEFTLMVVGESGLGKSTLINSLFLGDLYKNRQMPNV 119
            ...|     .::||.:||.|:.:|:|:.||:|.||.|||:|.||:|||.|||           |:
 Worm   138 HTGRVMQLNGHVGFDSLPHQLVKKAVEAGFQFNLMCVGETGTGKTTLIESLF-----------NM 191

  Fly   120 EERIE------KTTKVEKKTMDIEERGVRLRLTVVDTPGFGDAINCEDSWRVCTQYIDEQFRQYF 178
            :...|      ||.::...|.|:.|.|:|::|.:|:|.||||.::.:.|.:|...|::.||..|.
 Worm   192 KLDFEPCNHELKTVELRTCTKDVAEGGIRVKLRLVETAGFGDQLDKDKSAKVIVDYLESQFETYL 256

  Fly   179 TDESGLNRRNIQ---DNRVHCCLYFVPPWGHSLRQMDLDLIRRLHRKVNIVLVIGKADCLNKQEV 240
            .:|. ..||.:|   |:|:|.||||:.|.||.|:.:||..:|.|.::||::.||.|:|...|.|:
 Worm   257 QEEL-KPRRMLQYFNDSRIHACLYFISPTGHGLKALDLVTLRELAKRVNVIPVIAKSDTTCKDEL 320

  Fly   241 RKLKERILQDLEDNHIQLYQFPECDSDEDDDFKQQDRELKASIPFAVVGS-NTILEVAGKKVRGR 304
            .:.|.:||.:|:...|.:|.||    .:|:.....::|:..|:||||||| :.:.:..|:.||.|
 Worm   321 LRFKAKILSELKSQKIDIYTFP----TDDETVSTTNKEMNKSVPFAVVGSIDFVKKENGQMVRAR 381

  Fly   305 QYPWGVVNVEDPEHSDFIKLRTFLISTHMQDLKDTTQDVHYENFR---------------AQCIS 354
            |||||:|.||:..|.||:|||..|:.|::.:::..|.:..|||:|               .:.|.
 Worm   382 QYPWGIVEVENESHCDFVKLREALLRTNVDEMRQRTHESLYENYRRDRLRQMKIGDGETGPKIIE 446

  Fly   355 QISQHALRERGKLKRDSISSTNGFDAAISETDRLLLQKDEEIRRMQDMLTQMQEKLKQTHLMEMK 419
            :::|.....:.:..|..::....|...:..|       :.::|::::.|...:.::.:.:..|..
 Worm   447 KLAQKHREHQDEFSRRELTLREEFQKKLDVT-------EGDMRKVEEGLAAREREVHENYNREAS 504

  Fly   420 KNDSVI 425
            |.|..|
 Worm   505 KLDMEI 510

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sep4	NP_573147.2	CDC3	65..420	CDD:227352	124/379 (33%)
		CDC_Septin	82..357	CDD:206649	110/299 (37%)
unc-61	NP_872156.2	CDC_Septin	165..434	CDD:206649	109/284 (38%)
		DUF5401	<380..530	CDD:375164	33/138 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D845354at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2060
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.950