Protein Alignment Septin4 and unc-59

DIOPT Version :10

• Sequence 1: NP_573147.2
• Gene: Septin4 / 32646
• FlyBaseID: FBgn0259923
• Length: 427
• Species: Drosophila melanogaster
• Sequence 2: NP_493388.1
• Gene: unc-59 / 173233
• WormBaseID: WBGene00006793
• Length: 459
• Species: Caenorhabditis elegans
• Alignment Length: 404
• Identity: 152/404 - (37%)
• Similarity: 240/404 - (59%)
• Gaps: 38/404 - (9%)

  Fly    36 SSSSGIEAVKCRPPIYPKPKTPSFDKDRDYIGFATLPEQVHRKSVKRGFEFTLMVVGESGLGKST 100
            |||...|::          :|....::.:|.|||..|.||.|::||.||:|||||||.|||||||
 Worm     8 SSSRNDESL----------RTGQHKENPNYWGFANFPNQVFRRAVKNGFDFTLMVVGRSGLGKST 62

  Fly   101 LINSLFLGDLYKNRQMPNVEERIE-------KTTKVEKKTMDIEERGVRLRLTVVDTPGFGDAIN 158
            .||:|||.::      .|:.|:..       .|.:||:|.:.:.|..|.|.||:|||||||||:|
 Worm    63 FINTLFLAEI------NNLNEKESAPTHPHPSTVRVEEKLVKLVENSVSLNLTLVDTPGFGDAVN 121

  Fly   159 CEDSWRVCTQYIDEQFRQYFTDESGLNR-RNIQDNRVHCCLYFVPPWGHSLRQMDLDLIRRLHRK 222
            ....|.....|::.:|.:.|.:|:.::| ..|.|..||.||||:.|.||.|:.:|::|::.||.:
 Worm   122 NSKCWEPIVNYVESKFFEQFCEETRIDRGEKIVDKCVHLCLYFIEPSGHGLKPIDIELMKHLHGR 186

  Fly   223 VNIVLVIGKADCLNKQEVRKLKERILQDLEDNHIQLYQFPECDSDEDDDFKQQDRELKASIPFAV 287
            ||||.||.|||||.:.|:.:.|::|::|.|...|:||:|||.:....|  |....:|:.::|||:
 Worm   187 VNIVPVISKADCLTRDELLRFKKQIVKDAETAEIKLYKFPELEDPYTD--KVAIEKLRKALPFAI 249

  Fly   288 VGSNTILEVAGKKVRGRQYPWGVVNVEDPEHSDFIKLRTFLISTHMQDLKDTTQDVHYENFRAQC 352
            :|||.:.|..|||:|.|:||||.|.||:.:|:||:.||..:|.|::.|:.|.|::|||||||.:.
 Worm   250 IGSNMLKEKDGKKIRYREYPWGTVEVENMQHNDFLTLRDMIIRTNLIDMIDVTRNVHYENFRFRQ 314

  Fly   353 ISQISQ---------HALRERGKLKRDSISSTNGFDAAISE-TDRLLLQKDEEIRRMQDMLTQMQ 407
            :..:.:         |...||.:.::|.....|..:...:| |.....:.||.:..::::..|.:
 Worm   315 MEGLPKNEKNRDPFTHLEEERRQKEQDLDEKRNTLEKVFTEKTSARKKRSDERMSALEELEQQNK 379

  Fly   408 EKL--KQTHLMEMK 419
            :|:  |:..::.::
 Worm   380 QKIDAKRAEIIRLR 393

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Septin4	NP_573147.2	CDC_Septin	82..357	CDD:206649	125/282 (44%)
unc-59	NP_493388.1	CDC_Septin	44..318	CDD:206649	125/281 (44%)
		DUF4200	328..>401	CDD:464003	12/66 (18%)