Protein Alignment Septin4 and Septin10

DIOPT Version :10

• Sequence 1: NP_573147.2
• Gene: Septin4 / 32646
• FlyBaseID: FBgn0259923
• Length: 427
• Species: Drosophila melanogaster
• Sequence 2: NP_001365992.1
• Gene: Septin10 / 103080
• MGIID: 1918110
• Length: 456
• Species: Mus musculus
• Alignment Length: 393
• Identity: 144/393 - (36%)
• Similarity: 226/393 - (57%)
• Gaps: 53/393 - (13%)

  Fly    65 YIGFATLPEQVHRKSVKRGFEFTLMVVGESGLGKSTLINSLFLGDLYKNRQMPNVEERIEKT--- 126
            ::||.:||:|:..:|:::||.|.::.|||:|:|||||||:||         ..|.|| :|.:
Mouse    23 HVGFESLPDQLVDRSIEQGFCFNILCVGETGIGKSTLINTLF---------NTNFEE-LESSHFC 77

  Fly   127 --TKVEKKTMDIEERGVRLRLTVVDTPGFGDAINCEDSWRVCTQYIDEQFRQYFTDESGLNRR-- 187
              .::..:|.:::|..|||:||:|:|.||||.||.|||::....|||:||..|..:|..:.|.
Mouse    78 PCVRLRAQTYELQESNVRLKLTIVNTVGFGDQINKEDSYQPIVDYIDDQFEAYLQEELKIKRALF 142

  Fly   188 NIQDNRVHCCLYFVPPWGHSLRQMDLDLIRRLHRKVNIVLVIGKADCLNKQEVRKLKERILQDLE 252
            |..|:|:|.||||:.|.|||||.:||..::.|..||||:.:|.|||.::|.|::|.|.:::.:|.
Mouse   143 NYHDSRIHVCLYFIAPTGHSLRTLDLLTMKSLDNKVNIIPLIAKADTISKSELQKFKMKLMNELV 207

  Fly   253 DNHIQLYQFPECDSDEDDDFKQQDRELKASIPFAVVGSNTILEVAGKKVRGRQYPWGVVNVEDPE 317
            .|.:|:||||    .:||...:.:..:...:|||||||...::|..|.|:|||||||:|.||:..
Mouse   208 INGVQIYQFP----TDDDTTSKINGAMNGHLPFAVVGSMDEIKVGNKMVKGRQYPWGIVQVENEN 268

  Fly   318 HSDFIKLRTFLISTHMQDLKDTTQDVHYENFRAQCISQ---------------------ISQHAL 361
            |.||:|||..||.|:|:||::.|...|||.:| :|..|                     ..:|..
Mouse   269 HCDFVKLREMLICTNMEDLREQTHMRHYELYR-RCKLQEMGFVDMGPENKPLSLQETYEAKRHEF 332

  Fly   362 -----RERGKLKRDSISSTNGFDAAISETDRLLLQKDEEIRRMQDMLTQMQEKLKQTHLMEMKKN 421
                 |:..::|:..:......:|.:.|.:|.|..|.|.::|:     ..:|::|......|.:.
Mouse   333 YGERQRKEEQMKQMFVQRVKEKEAILKEAERELQAKFEHLKRI-----HQEERMKLEEKRRMLEE 392

  Fly   422 DSV 424
            :||
Mouse   393 ESV 395

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Septin4	NP_573147.2	CDC_Septin	82..357	CDD:206649	123/302 (41%)
Septin10	NP_001365992.1	CDC_Septin	40..308	CDD:206649	123/282 (44%)
		G1 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01056	50..57		4/6 (67%)
		G3 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01056	102..105		1/2 (50%)
		G4 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01056	185..188		1/2 (50%)
		PTZ00121	<274..426	CDD:173412	31/128 (24%)