DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sep4 and septin4

DIOPT Version :9

Sequence 1:	NP_573147.2	Gene:	Sep4 / 32646	FlyBaseID:	FBgn0259923	Length:	427	Species:	Drosophila melanogaster
Sequence 2:	XP_002933653.2	Gene:	septin4 / 100485625	XenbaseID:	XB-GENE-983580	Length:	634	Species:	Xenopus tropicalis

Alignment Length:	389	Identity:	227/389 - (58%)
Similarity:	294/389 - (75%)	Gaps:	24/389 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 CRP----PIYP-KPKTP--------SFDKDRDYIGFATLPEQVHRKSVKRGFEFTLMVVGESGLG 97
            |.|    |:.| :||:|        ||::||:|:||||||.|:|||.||:||||||||.||||||
Frog   248 CCPQALTPLSPSRPKSPWGRFDPYDSFEEDREYVGFATLPNQMHRKYVKKGFEFTLMVAGESGLG 312

  Fly    98 KSTLINSLFLGDLYKNRQMPNVEERIEKTTKVEKKTMDIEERGVRLRLTVVDTPGFGDAINCEDS 162
            ||||||||||.|||::|.:.:.|||:.:|.::.|:|:||:|:|||||||||||||:|||||.|..
Frog   313 KSTLINSLFLTDLYRDRHILSPEERVTQTVEIVKQTVDIQEKGVRLRLTVVDTPGYGDAINNEIC 377

  Fly   163 WRVCTQYIDEQFRQYFTDESGLNRRNIQDNRVHCCLYFVPPWGHSLRQMDLDLIRRLHRKVNIVL 227
            |:....|||:||.|||.|||||||||:||.||||||||:.|.||.:|.||::.::.|..|||||.
Frog   378 WKPVADYIDQQFEQYFRDESGLNRRNLQDTRVHCCLYFLSPLGHGMRPMDIEFLQALQDKVNIVP 442

  Fly   228 VIGKADCLNKQEVRKLKERILQDLEDNHIQLYQFPECDSDEDDDFKQQDRELKASIPFAVVGSNT 292
            ::||||.|...|:::.|:||..:::...|::|||||||.|||:||||||.|||.||||||:||||
Frog   443 ILGKADSLTPTELQQKKQRIRDEIDKYGIRIYQFPECDPDEDEDFKQQDIELKKSIPFAVIGSNT 507

  Fly   293 ILEVAGKKVRGRQYPWGVVNVEDPEHSDFIKLRTFLISTHMQDLKDTTQDVHYENFRAQCISQIS 357
            |:||.|::||||.||||||.||:.||.|||||||.||.||||||||.|::.||||:|||||..::
Frog   508 IIEVNGRRVRGRMYPWGVVEVENEEHCDFIKLRTMLIRTHMQDLKDVTRETHYENYRAQCIQNLT 572

  Fly   358 QHALRERGKLKRDSISSTNGFDAAI--------SETDRLLLQKDEEIRRMQDMLTQMQEKLKQT 413
            |..:|||   .|:.::..:|.|..|        .||.||:.:||||:|||.::|.:||.::|.:
Frog   573 QRVVRER---NRNKLTRESGTDFPIPSMPPSPDHETQRLIREKDEELRRMHEVLQKMQRQMKDS 633

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sep4	NP_573147.2	CDC3	65..420	CDD:227352	216/357 (61%)
Sep4	NP_573147.2	CDC_Septin	82..357	CDD:206649	180/274 (66%)
septin4	XP_002933653.2	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	400	1.000	Domainoid score	I727
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	465	1.000	Inparanoid score	I1510
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D452703at33208
OrthoFinder	1	1.000	-	-		FOG0000103
OrthoInspector	1	1.000	-	-		otm47686
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X204
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	6.060