Protein Alignment Axs and ano2b

DIOPT Version :9

• Sequence 1: NP_476777.1
• Gene: Axs / 32645
• FlyBaseID: FBgn0000152
• Length: 646
• Species: Drosophila melanogaster
• Sequence 2: NP_001314787.1
• Gene: ano2b / 566373
• ZFINID: ZDB-GENE-060503-62
• Length: 1065
• Species: Danio rerio
• Alignment Length: 902
• Identity: 190/902 - (21%)
• Similarity: 308/902 - (34%)
• Gaps: 324/902 - (35%)

  Fly    21 FRRQRSLKLEALQRQRTLDSND----GVEGL---GADTEPFDKTHIVIIFT--------EKAKLR 70
            :|::.|::....|.:.::.||.    |||..   |...||.:    |::..        ||..:|
Zfish   110 YRKRSSIRGSPSQHRLSIISNGSYHLGVEEKDPEGGKEEPAE----VVVDVGPPDPAEGEKIMIR 170

  Fly    71 HCQDVEKIIQEFGIQTTLEIVGKT--EKYLYLSASVDTLLRLADAAELEKMT------------- 120
              ::.|..:::.|::...:...|.  ..::.|.|....|.|.|:..:::..|
Zfish   171 --EEFEGSLKDAGLEIERDKENKAHGHAFIRLHAPWQVLSREAEFLKIKVQTKKSYELREEKGLA 233

  Fly   121 ----------------------TTHSMQKFNHGCIS------------DFLLPGMGKEQIL---- 147
                                  ..:|..||...|.|            |.......:.:|:
Zfish   234 ATMNEVWRKLNQPFQPKVPHQEQENSRTKFLTHCFSRDKLHLYNIQSKDTFFDNATRSRIVYEIL 298

  Fly   148 ------RYCEIPVLIKDVIQDGIKSYVQKGYIEDMFPLHD----------------ILYLERFNW 190
                  |.|:..         ||.:.:..|..:..|||||                :|:.|...:
Zfish   299 RRTACTRTCQTM---------GITTLIANGVYDSAFPLHDGDFHSSGQAEGKNERQLLHDEWARY 354

  Fly   191 NLKRTKLPIEDIRNYFGSSIGLYFGFIEFYTKALIFPSLFGILQYVF-----DLNI--------- 241
            .......||:.||.|||..|||||.::..||:.||..|:.||:.:.:     :.|:
Zfish   355 GAFYKYQPIDLIRKYFGEKIGLYFAWLGVYTQLLIPASVVGIIVFFYGWATVETNVPSQEMCDET 419

  Fly   242 ------------------SLVCS------------------FYVVWTTIFLELWKRKCAGYSYRW 270
                              |..|.                  |..:|..:|||.|||:....:|.|
Zfish   420 QNFTMCPLCDRVCDYWQLSTACGTARASHLFDNPATVFFAIFMSLWAAMFLEHWKRRQISLNYSW 484

  Fly   271 GTIEMSSLDK-PRSAY---------------------------TGQLKPDP---------ITGKM 298
            ....|...:: ||..|                           :|:|..|.         ..|..
Zfish   485 DLTGMEEEEEHPRPKYETILLQKRQRKKKNKKNKNEPERVVDESGELGKDKWRQRLLSAMAAGNP 549

  Fly   299 TLHYPMRY-TYLQMYCISYPVVLGC--VVAAGWFALYQFQIEAEVLADFGPDS--------WLLY 352
            |.|..:.: ..|..|.|:...:|..  |..:..|::..::|....|....||.        .:..
Zfish   550 TGHEKLTWRDRLPGYLINISSILFMFGVTCSAVFSVIIYRITISALMAMSPDPDVKSNVRVTVTA 614

  Fly   353 VPVIVQSVLIAIFSWAYEKLATFLTNLENHRTRSQYDRHRVNKLMLFEIVNNFFSQFYIAF---- 413
            ..||:..|:|.|....|..:|.:||.||..:|.:.::...:.|..:.:.:|.:...||:||
Zfish   615 TAVIINLVVILILDEIYGMVAAWLTELEIPKTETNFEERLILKAFVLKFMNAYAPIFYVAFFKGR 679

  Fly   414 ----------VLHDLR-----------QLKYQLMMQLLVFQLLCIAQ----EIGIP----LLAVL 449
                      |.||.|           :|..||.:.:|..||:   |    |||||    |...|
Zfish   680 FAGRPGDYVYVFHDYRMEECAPGGCLIELCIQLSIIMLGKQLI---QNNVFEIGIPKLKKLCRTL 741

  Fly   450 RQKYAEFRHREVAEEKLRSISDLPRYEQSFYESGLDEYHSTYEDYLQVCIQFGFVVLFAAVAPFA 514
            :.|..|  .:|:.|:.       .|.:|...:..|:.:.....:|:::.||||||.||.|..|.|
Zfish   742 KDKDRE--PKEIVEQP-------GRRQQWHMDYDLEPFDGLTPEYMEMIIQFGFVSLFVASFPLA 797

  Fly   515 AIGALLNNVFAVHIDMWKLCNIFKRPFARRAKNIGAWQLAFELLSVMSLLSNCGLL--------- 570
            .:.||||||..:.:|..|.....:||.|.|.|:||.|......|...|::.|..::
Zfish   798 PLFALLNNVIEIRLDAKKFVTELRRPDAVRTKDIGIWYNILSGLGKFSVIINAFVISFTSDFIPR 862

  Fly   571 ---------------FLQP-----NVKDFFSHWLPSVPD-------------------------- 589
                           |:..     ||.:|....:||..|
Zfish   863 LVYQYMYSETGTMHGFINHTLSYFNVSNFKPGTMPSTSDITVCRYKDYREPPWSNEPYQFSKQYW 927

  Fly   590 ------LSFVI-FEHLLLGLKFLIHKVIHERPRWVRIGLLKADFETSQALKQLKKFK 639
                  |.||| |::|::.:..|:..:|.:.|:.:.              :||||.|
Zfish   928 SVLAARLGFVILFQNLVIIMSMLVAWLIPDMPKNIS--------------EQLKKDK 970

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Axs	NP_476777.1	Anoctamin	202..623	CDD:282414	140/613 (23%)
ano2b	NP_001314787.1	Anoct_dimer	94..363	CDD:292796	43/267 (16%)
		Anoctamin	366..968	CDD:282414	142/627 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1263362at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920