Protein Alignment Axs and ano5b

DIOPT Version :9

• Sequence 1: NP_476777.1
• Gene: Axs / 32645
• FlyBaseID: FBgn0000152
• Length: 646
• Species: Drosophila melanogaster
• Sequence 2: XP_005168948.1
• Gene: ano5b / 560102
• ZFINID: ZDB-GENE-061215-108
• Length: 930
• Species: Danio rerio
• Alignment Length: 836
• Identity: 183/836 - (21%)
• Similarity: 321/836 - (38%)
• Gaps: 253/836 - (30%)

  Fly    33 QRQRTLDSNDGVEGLGADTEPFD-----KTHIVIIFTEKAKLRHCQDVEKIIQEFGI-------Q 85
            :|:|..::|....||..:||...     |||.:.|......|....||.||...|.:       :
Zfish    98 ERRREFEANLEKAGLELETEDKSESDDRKTHYLKIHAPWEVLATYADVLKIKVPFKVSDIPKARE 162

  Fly    86 TTLEIVGKTEKYLYLSASV---DTLLRLADAAELEKMTTTHSMQKFNHGCI--SDFLLPGMGKEQ 145
            ..||         :||...   :.::|    .|.:..|......|.:...|  .|...|...:.:
Zfish   163 VPLE---------WLSHPFRLPENIMR----PEPDYFTAPFDKSKVDFFLIDDKDTFFPPSTRNR 214

  Fly   146 ILRYCEIPVLI---------KDVIQDGIKSYVQKGYIEDMFPLHDILY--------LERFNWNLK 193
            |:.|    :|.         |:..:.||...:..|.....:||||..|        .|...::|.
Zfish   215 IVYY----ILTRCPYYKEDRKEKDKTGINRLLNNGTYTSAYPLHDCRYWKKAQDMQCESERYHLY 275

  Fly   194 R---------TKLPIEDIRNYFGSSIGLYFGFIEFYTKALIFPSLFGILQYVFDL-----NIS-- 242
            |         .:.|:..|:.|:|..||:||.::.|||:.|.:.::.|::.:|:.:     ||:
Zfish   276 RYWARFLCFYKEQPLNLIKKYYGEKIGIYFAWLGFYTEMLFYAAVMGVICFVYGVLSYEDNITSK 340

  Fly   243 ----------LV--------CSFYV---------------------------VWTTIFLELWKRK 262
                      :|        ||::.                           :|.|:|||.|||:
Zfish   341 EICDPKIGGMIVMCPLCDKKCSYWKLNSTCLSSWQSHLFDNEGTVFFAMFMGIWVTLFLEFWKRR 405

  Fly   263 CAGYSYRWGTIEMSSLDKP---RSAY----TGQLKPDPITGKMTLHYPMRYTYLQMYCISYPVVL 320
            .|...|.|..::.....:.   |..|    ||: :.:.||.:|..:.|.. :....:|:|...||
Zfish   406 QARLEYEWDLVDFEEEQQQLQIRPEYEQKCTGR-RLNRITQEMEPYLPFP-SKCARFCLSGATVL 468

  Fly   321 -------GCVVAAGWFALYQFQIEAEVLADFGPDSWLLYVPVI------------VQSVLIAIFS 366
                   .|::....:.|..:...|.|:.|.......|...:|            :..|:|.|.:
Zfish   469 FWTCLIVACIMGVIAYRLAVYAAFASVMKDSSTSKIQLVGSLITPQLATSVTASCINFVIILILN 533

  Fly   367 WAYEKLATFLTNLENHRTRSQYDRHRVNKLMLFEIVNNFFSQFYIAF------------------ 413
            :.||.:|.::|::|..:|..:|:.....|:.:|:.||.:.|.||:||
Zfish   534 FLYEHVAIWITDMEIPKTHLEYENKLTMKMFMFQFVNYYSSCFYVAFFKGKFVGYPGNYSYMFGK 598

  Fly   414 --VLHD--------LRQLKYQLMMQLLVFQLLCIAQEIGIPLLAVLRQKYAEFRHREVAEEKLRS 468
              .|.:        |.:|..||::.:...|::...||..:||   :|..::..:.|...|
Zfish   599 WSTLRNEECAPGGCLIELTTQLLIVMAGKQMVGNVQEALLPL---VRNWWSSRKGRSHPE----- 655

  Fly   469 ISDLPRYEQSFYESGLDEYHSTYEDYLQVCIQFGFVVLFAAVAPFAAIGALLNNVFAVHIDMWKL 533
             |...|:||........::...|| ||::.|||||:.||.|..|.|.:.||.||:..|.:|.||.
Zfish   656 -STYSRWEQDHDLQNFSQFGLFYE-YLEMVIQFGFITLFVASFPLAPLLALFNNILEVRVDAWKF 718

  Fly   534 CNIFKRPFARRAKNIGAWQLAFELLSVMSLLSNC-----------GLLFL---QPNV-------- 576
            ...|:||.|.:|:|||||:....::::||:::|.           .|::|   .|.:
Zfish   719 TTQFRRPMAAKARNIGAWEEILNVVAIMSVVTNAFIMAFTSDMIPRLVYLYAYHPGIEANMTGYI 783

  Fly   577 -------------------------------------KDF---------FSH----WLPSVPDLS 591
                                                 :|:         ::|    |......|:
Zfish   784 TNSLSIYNISQIPEDNLPEAGENPSWFNSSTITTCRYRDYRYPPGHLRQYTHTMQFWHILAAKLA 848

  Fly   592 F-VIFEHLLLGLKFLIHKVIHERPRWVRIGLLKADFETSQALK--QLKKFKAEANK 644
            | :|.||::..:||.:..:|.:.|..|:..:.:..|...:.|.  :::|.|.:.::
Zfish   849 FIIIMEHVVFVVKFFVAWLIPDVPSEVKARIKRERFLVQEYLHNYEVEKLKMQLSQ 904

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Axs	NP_476777.1	Anoctamin	202..623	CDD:282414	135/599 (23%)
ano5b	XP_005168948.1	Anoct_dimer	73..290	CDD:292796	43/208 (21%)
		Anoctamin	293..883	CDD:282414	135/601 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1263362at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920