Protein Alignment Axs and ano3

DIOPT Version :9

• Sequence 1: NP_476777.1
• Gene: Axs / 32645
• FlyBaseID: FBgn0000152
• Length: 646
• Species: Drosophila melanogaster
• Sequence 2: XP_021326430.1
• Gene: ano3 / 553392
• ZFINID: ZDB-GENE-111031-3
• Length: 1026
• Species: Danio rerio
• Alignment Length: 672
• Identity: 156/672 - (23%)
• Similarity: 259/672 - (38%)
• Gaps: 196/672 - (29%)

  Fly   162 DGIKSYVQKGYIEDMFPLHD-------------------ILYLERFNWNLKRTKLPIEDIRNYFG 207
            :||...:.....|..||.|:                   :||.....|.:.....|::.||.|||
Zfish   355 EGINRLLGNSTYEAAFPPHEGCYKSRHPIKTHGAQNHRHLLYERWARWGIWYKYQPLDLIRRYFG 419

  Fly   208 SSIGLYFGFIEFYTKALIFPSLFGILQYVFDL---------------NISLVCS----------- 246
            ..|||||.::.:||..||..:|.|:..:::.|               |.:::|.
Zfish   420 EKIGLYFAWLGWYTGMLIPAALVGLFVFLYGLFTMDSSQVSKEICEANTTVMCPMCEGNCSSWTL 484

  Fly   247 -----------------------FYVVWTTIFLELWKRKCAGYSYRWGTIEMSSLD-KP------ 281
                                   |..:|.|:|||.|||:.|..:|.|..|:....: ||
Zfish   485 SDSCVYAKVTHLFDNGGTVFFAIFMAIWATVFLEFWKRRRAELTYDWDLIDWEEEECKPCVMVCS 549

  Fly   282 -------RSAYTGQLKPDPITGKMTLHYPM--RYTYLQM------YCISYPVVLGCVVAAGWFAL 331
                   .:.|:.:.:.:||:||.....|:  :.:.|.:      :.||  :||..|.|...|.|
Zfish   550 EELRPQFEAKYSRKERVNPISGKPEPFQPLTDKLSRLMVSVSGIFFMIS--LVLTAVFAVVVFRL 612

  Fly   332 YQFQIEAEVLADFGPDSWLLYVP---VIVQSVLIAIFSWAYEKLATFLTNLENHRTRSQYDRHRV 393
            ...:.......:|...:|.....   |.:..::|...:..|||:|..|||||:.||.|:::....
Zfish   613 IAMEKFVSFQWEFVKKNWQFATSGTGVCINFMIIMSLNVVYEKVAYLLTNLEHPRTESEWENSFA 677

  Fly   394 NKLMLFEIVNNFFSQFYIAFVL----------------------HD---LRQLKYQLMMQLLVFQ 433
            .|:.||:.||...|.|||||.|                      |.   |..|..|:.:.:::.|
Zfish   678 LKMFLFQFVNLNSSTFYIAFFLGRFAGRPGDYNKLFNRWRMEECHPSGCLIDLCLQMGVIMVLKQ 742

  Fly   434 LLCIAQEIGIPLLAVLRQKYAEFRHREVAEEKLRSISDLPRYEQSFYESGLDEYHSTYEDYLQVC 498
            :.....|:|.|||    |.:...|..:.|.|:..|..:||::::.:....::. |...::||::.
Zfish   743 IWNNFMELGYPLL----QNWWSRRKMKRAGEQSNSKEELPQWDRDWNLQPMNA-HGLVDEYLEMV 802

  Fly   499 IQFGFVVLFAAVAPFAAIGALLNNVFAVHIDMWKLCNIFKRPFARRAKNIGAWQLAFELLSVMSL 563
            :||||..:|.|..|.|.:.|||||:..:.:|.:|....::||...||.:||.|....|.:.|:::
Zfish   803 LQFGFTTIFVAAFPLAPLLALLNNIIEIRLDAYKFVTQWRRPMPARATDIGIWHGVLEGIGVVAV 867

  Fly   564 LSNCGLLFLQ--------------PNVKDFFSH-------------------------------- 582
            ::|..::.:.              |.|...:.|
Zfish   868 ITNAFVIAITSDYIPRFVYAIKYGPCVDKGYRHEKCLRGYLNNSLSVFDMGELRNGSYENQYCRY 932

  Fly   583 -------WLPS------------VPDLSFVI-FEHLLLGLKFLIHKVIHERP-----RWVRIGLL 622
                   |.|.            ...|:|:| ||||:.|:|..|..:|.:.|     |..|...|
Zfish   933 RDYRAPPWSPEPYEFTLQFWHVLAARLAFIIVFEHLVFGIKTFIAHMIPDMPKDLCDRMRREKYL 997

  Fly   623 KADFETSQALKQLKKFKAEANK 644
            ..:......|:.|:|.:.:..|
Zfish   998 MQEMVYEAELEHLQKERKKNGK 1019

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Axs	NP_476777.1	Anoctamin	202..623	CDD:282414	141/590 (24%)
ano3	XP_021326430.1	Anoct_dimer	163..411	CDD:318420	9/55 (16%)
		Anoctamin	414..994	CDD:309610	140/586 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1263362at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920