Protein Alignment Axs and Ano7

DIOPT Version :9

• Sequence 1: NP_476777.1
• Gene: Axs / 32645
• FlyBaseID: FBgn0000152
• Length: 646
• Species: Drosophila melanogaster
• Sequence 2: NP_001004071.1
• Gene: Ano7 / 367318
• RGDID: 1302987
• Length: 860
• Species: Rattus norvegicus
• Alignment Length: 629
• Identity: 150/629 - (23%)
• Similarity: 246/629 - (39%)
• Gaps: 174/629 - (27%)

  Fly   163 GIKSYVQKGYIEDMFPLHD-------------------ILYLERFNWNLKRTKLPIEDIRNYFGS 208
            ||...:.:|.....|||||                   :|:.....|...|...|::.:|.|||.
  Rat   219 GIDQLLAEGVFSAAFPLHDGPFSVVPESSQVLGLTQRQVLFKHWARWGKWRKYQPLDHVRRYFGE 283

  Fly   209 SIGLYFGFIEFYTKALIFPSLFGILQYV---------------------FDL----------NIS 242
            .:.|||.::.|||..|:..::.|.:.::                     ||:          .:|
  Rat   284 KVALYFAWLGFYTGWLLPAAVVGTVVFLAGCFLVFSDVPTQELCHSSDTFDMCPLCSDCSFWLLS 348

  Fly   243 LVCS------------------FYVVWTTIFLELWKRKCAGYSYRWGTIEMSSLD---KPRSAYT 286
            ..|:                  |..:|..:.||.||||.|..:|||...:...::   :|:.|.|
  Rat   349 SACTLAQAGRLFDHGGTVFFSLFMALWAVLLLEYWKRKNATLAYRWDCSDYEDIEERPRPQFAAT 413

  Fly   287 GQLKP-DPITGKMTLHYPMRYTYLQMYCISYPVVLGCVVAAGWFALYQFQIEAEVLADFGPDS-- 348
            ..:.. :||||:...::|.:....:|  ::..|||..:||.....|....:...|:|.....|
  Rat   414 APMTALNPITGEDEPYFPEKNRVRRM--LAGSVVLLMMVAVVIMCLVSIILYRAVMAIIVSKSNN 476

  Fly   349 -----WLLYVP----VIVQSVLIAIFSWAYEKLATFLTNLENHRTRSQYDRHRVNKLMLFEIVNN 404
                 |...:.    .:|..|.|.|.|..|..||..||..|.|||::.::.....|:.:|:.||.
  Rat   477 AFLSAWASRIASLTGSVVNLVFILILSKVYVILAQVLTRWEMHRTQTAFEDAFTLKVFIFQFVNF 541

  Fly   405 FFSQFYIAF-----------------VLHD-------LRQLKYQLMMQLLVFQLLCIAQEIGIPL 445
            :.|..||||                 |.::       |.:|..:|::.::..|::...||:.:|.
  Rat   542 YASPVYIAFFKGRFVGYPGNYHTLFGVRNEECPAGGCLSELAQELLVIMVGKQIINNVQEVLVPK 606

  Fly   446 LAVLRQKYAEFRHREVAEEKLRSISDLPRYEQSFYE----SGLDEYHSTYEDYLQVCIQFGFVVL 506
            |....||....|       |...:...|...::.||    .||      :.:||::.:|||||.:
  Rat   607 LKGCWQKLCSRR-------KKAGMGANPAPWEADYELLPCEGL------FHEYLEMVLQFGFVTI 658

  Fly   507 FAAVAPFAAIGALLNNVFAVHIDMWKLCNIFKRPFARRAKNIGAWQLAFELLSVMSLLSNCGLL- 570
            |.|..|.|.:.|||||...:.:|..|....::||.|.||::||.|......|:.::::||..||
  Rat   659 FVAACPLAPLFALLNNWVEIRLDARKFVCEYRRPVAERAQDIGIWFHILAGLTHLAVISNAFLLA 723

  Fly   571 ----FL---------QPNVKDFFSHWLPSVPD--------------------------------- 589
                ||         .|:::.|.:..|...|.
  Rat   724 FSSDFLPRVYYSWTRAPDLRGFLNFTLARAPPTFTSAHNRTCRYRAFRDDDGHYSPTYWTLLAIR 788

  Fly   590 LSFVI-FEHLLLGLKFLIHKVIHERPRWVRIGLLKADFETSQAL 632
            |:||| |||::......:..::.:.|..|.|.:.:..:...|||
  Rat   789 LAFVIVFEHVVFSTGRFLDLLVPDIPESVEIKVKREYYLAKQAL 832

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Axs	NP_476777.1	Anoctamin	202..623	CDD:282414	135/560 (24%)
Ano7	NP_001004071.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	24..50
		Anoct_dimer	54..274	CDD:292796	11/54 (20%)
		Anoctamin	277..824	CDD:282414	135/561 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1263362at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920