Protein Alignment Axs and Ano1

DIOPT Version :9

• Sequence 1: NP_476777.1
• Gene: Axs / 32645
• FlyBaseID: FBgn0000152
• Length: 646
• Species: Drosophila melanogaster
• Sequence 2: XP_017444724.1
• Gene: Ano1 / 309135
• RGDID: 1310786
• Length: 1066
• Species: Rattus norvegicus
• Alignment Length: 856
• Identity: 182/856 - (21%)
• Similarity: 308/856 - (35%)
• Gaps: 295/856 - (34%)

  Fly    17 ENQLFRRQR---SLKLEALQRQRTLDSNDGVEGLGADTEPFDKT----HIVIIFTEKAKLR---- 70
            :::.|||:.   :|....|:.:|  |.:..:.|:|     |.|.    |::....|..||:
  Rat   180 DDKRFRREEYEGNLLEAGLELER--DEDTKIHGVG-----FVKIHAPWHVLCREAEFLKLKMPTK 237

  Fly    71 ---HCQD-----------VEKI-------IQEFGIQTTLEI---VGKTEKYLY----LSASVDTL 107
               |..:           ::||       :.|...|||..:   ..:.:::|:    ..:..|:.
  Rat   238 KVYHISETRGLLKTINSVLQKITDPIQPKVAEHRPQTTKRLSYPFSREKQHLFDLTDRDSFFDSK 302

  Fly   108 LRLADAAELEKMTT-THSMQKFNHGCISDFLLPGMGKEQIL----RYCEIPVLIKDVIQDGIKSY 167
            .|.....|:.|.|| |.:......|       .|..|:..|    |.|.         :.||.|.
  Rat   303 TRSTIVYEILKRTTCTKAKYSMGQG-------EGRRKDSALLSKRRKCG---------KYGITSL 351

  Fly   168 VQKGYIEDMFPLHD--------------ILYLERFNWNLKRTKLPIEDIRNYFGSSIGLYFGFIE 218
            :..|.....:||||              :||.|..::.:.....||:.:|.|||..:||||.::.
  Rat   352 LANGVYSAAYPLHDGDYEGDNVEFNDRKLLYEEWASYGVFYKYQPIDLVRKYFGEKVGLYFAWLG 416

  Fly   219 FYTKALIFPSLFGILQYVF-----DLNI---------------------------SLVCS----- 246
            .||:.||..|:.|::.:::     |.||                           |..|:
  Rat   417 AYTQMLIPASIVGVIVFLYGCATVDENIPSMEMCDQRHNITMCPLCDKTCSYWKMSSACATARAS 481

  Fly   247 -------------FYVVWTTIFLELWKRKCAGYSYRWGTI-----EMSSLDKPRSAYTGQ----- 288
                         |..:|...|:|.||||....:|||...     |.:..|.||:.|..:
  Rat   482 HLFDNPATVFFSVFMALWAATFMEHWKRKQMRLNYRWDLTGFEEEEEAVKDHPRAEYEARVLEKS 546

  Fly   289 -------------LKPDP----------------ITGKMTL----HYPMRYTYLQ----MYCISY 316
                         :..:|                :|.|:.|    .:|..:|.|.    |..:::
  Rat   547 LRKESRNKEKRRNVPEEPTNKWKQRVRTAMAGVKLTDKVKLTWRDRFPAYFTNLVSIIFMIAVTF 611

  Fly   317 PVVLGCVVAAGWFALYQFQIEAEVLADFGPD------SWLLYVPVIVQSVLIAIFSWAYEKLATF 375
            .:|||.::       |:....|.:..:..|.      ..:....||:..|:|.:....|..:|.:
  Rat   612 AIVLGVII-------YRISTAAALAMNSSPSVRSNIRVTVTATAVIINLVVIILLDEVYGCIARW 669

  Fly   376 LTNLENHRTRSQYDRHRVNKLMLFEIVNNFFSQFYIAF--------------VLHDLR------- 419
            ||.:|..:|...::.....|..|.:.||::...||:||              :....|
  Rat   670 LTKIEVPKTEKSFEERLTFKAFLLKFVNSYTPIFYVAFFKGRFVGRPGDYVYIFRSFRMEECAPG 734

  Fly   420 ----QLKYQLMMQLLVFQLLCIAQ----EIGIPLLAVLRQKYAEFRHREVAEEKLRSISDLPRYE 476
                :|..||.:.:|..||:   |    |||||.:... .:|.:.| |:...::...|....|||
  Rat   735 GCLMELCIQLSIIMLGKQLI---QNNLFEIGIPKMKKF-IRYLKLR-RQSPSDREEYIKRKQRYE 794

  Fly   477 QSFYESGLDEYHSTYEDYLQVCIQFGFVVLFAAVAPFAAIGALLNNVFAVHIDMWKLCNIFKRPF 541
            ..|   .|:.:.....:|:::.||||||.||.|..|.|.:.|||||:..:.:|..|.....:||.
  Rat   795 VDF---NLEPFAGLTPEYMEMIIQFGFVTLFVASFPLAPLFALLNNIIEIRLDAKKFVTELRRPV 856

  Fly   542 ARRAKNIGAWQLAFELLSVMSLLSNC-----------GLLFLQP------------------NVK 577
            |.|||:||.|......:..::::.|.           .|::|..                  ||.
  Rat   857 AIRAKDIGIWYNILRGVGKLAVIINAFVISFTSDFIPRLVYLYMYSQNGTMHGFVNHTLSSFNVS 921

  Fly   578 DFFSHWLPSVP-DLSF-------------------------------------VIFEHLLLGLKF 604
            ||.:...|:.| ||.:                                     ::|::|::.:..
  Rat   922 DFQNGTAPNDPLDLGYEVQICRYKDYREPPWSEHKYDISKDFWAVLAARLAFVIVFQNLVMFMSD 986

  Fly   605 LIHKVIHERPR 615
            .:..||.:.|:
  Rat   987 FVDWVIPDIPK 997

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Axs	NP_476777.1	Anoctamin	202..623	CDD:282414	133/613 (22%)
Ano1	XP_017444724.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1263362at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920