Protein Alignment Axs and anoh-1

DIOPT Version :9

• Sequence 1: NP_476777.1
• Gene: Axs / 32645
• FlyBaseID: FBgn0000152
• Length: 646
• Species: Drosophila melanogaster
• Sequence 2: NP_001255190.1
• Gene: anoh-1 / 176739
• WormBaseID: WBGene00010138
• Length: 840
• Species: Caenorhabditis elegans
• Alignment Length: 808
• Identity: 157/808 - (19%)
• Similarity: 290/808 - (35%)
• Gaps: 256/808 - (31%)

  Fly    47 LGADTE---PFDKTHIVIIFT-------EKAKLRHCQDVEKIIQEFGIQTTLEIVGKTEKYLYLS 101
            |.|.||   |:....|.|.|.       .::|.::.:..||.:|:.|:....:..|:|. :..:|
 Worm    20 LAATTEVDYPYFPFRISIDFVLVHNAAESRSKGKYREFFEKAVQKEGLIIRHQQSGQTH-FTLIS 83

  Fly   102 ASVDTLLRLADAAE--------------------LEKMTTTHSMQKF-------NHGCI------ 133
            .....|.|.|:.::                    |.::..|....:|       .||.:
 Worm    84 TPFHRLTREAEMSQMCFPLKDCQVKPGLPSCCIPLSQIFVTDDTVRFINAPFQRKHGSLFLNYHD 148

  Fly   134 --SDFLLPGMGKEQILRYCEIPVLIK-DVIQD------------------------------GIK 165
              |.|.....|      |....:|.| |:.:|                              |:.
 Worm   149 EKSFFTSSQRG------YLTYQILTKIDISKDLKGERLGESQDEPTDPSTSSITSDEQLRRKGLS 207

  Fly   166 SYVQKGYIEDMFPLHD----------------------ILYLE-------RFNWNLKRTKLPIED 201
            ..:.....|:.|.||.                      |..:|       ..||.......|:..
 Worm   208 WLLMSDVYEEAFVLHAPSKEEPYFKAMQNGSVKAYNEFISEIELDPRRSLSLNWERWYKFQPLNK 272

  Fly   202 IRNYFGSSIGLYFGFI-EFYTKALIFPS-LFGILQYVF-----------DLN------------- 240
            ||:|||..|..||.:. .|.|  |::|: :||::.:::           |.|
 Worm   273 IRDYFGEQIAYYFAWQGTFLT--LLWPAVIFGLVVFIYGFIDSISSAPLDWNHCKVVNFIGQTEN 335

  Fly   241 ------------ISLVCSFYV----------------VWTTIFLELWKRKCAGYSYRWGTIEMSS 277
                        .|:|..:::                :|.::|:::|||..:..||:|.:.:..:
 Worm   336 VACGMRNGVTLFFSMVTQWFMSSFDTKMNAFFAVFMSIWGSVFVQIWKRNNSVLSYQWNSDDFHA 400

  Fly   278 LDKPRSAYTG-QLKPDPITGKMTLHYPMRYTYLQMYC----ISYPVV-----LGCVVAAGWFALY 332
            ::..|..:.| ::|.|||||:.....|....|::|..    :|:.::     |..|.....:.:|
 Worm   401 IEPDRPEFRGSKVKEDPITGEDIWISPALARYIKMLASFVFVSFSMLVVVISLMLVTLLKIWMVY 465

  Fly   333 QFQIEAEVLADFGPDSWL--LYVPVIVQSVLIAIFSWAYEKLATFLTNLENHRTRSQYDRHRVNK 395
            .||...|    :....||  .::|.|:.::........|..|.:.|.:.|||||.|:::...:.|
 Worm   466 NFQCTKE----YTFHCWLSAAFLPSILNTLSAMGLGAIYSNLVSRLNSWENHRTESEHNNSLIVK 526

  Fly   396 LMLFEIVNNFFSQFYIAFV---LHDLRQ----------------------LKYQLMMQLLVFQLL 435
            :..|::||.:.|.||:||:   .|.|:.                      |..||:...|:....
 Worm   527 IFAFQMVNTYTSLFYVAFIRPESHGLQPNGLFGLGTEFKDTCLDDTCSSLLALQLLTHTLIKPFP 591

  Fly   436 CIAQEIGIPLLAVL---------RQKYAEFRHREVAEEKLR-----SISDLPRYEQSFYESGLDE 486
            ...:::.:|....|         .:...|....:.|...:|     |..|...:|.:
 Worm   592 KFFKDVVLPYFVKLFRLRMYTSRTEARVEIEDDDQANVLVREWLKPSAGDFVLWEMN-------- 648

  Fly   487 YHSTYEDYLQVCIQFGFVVLFAAVAPFAAIGALLNNVFAVHIDMWKLCNIFKRPFARRAKNIGAW 551
                     :..|.||..::||::.|.|.:.||:.....:.||..:|....::|.......||.|
 Worm   649 ---------EKIILFGTTMMFASLFPLAPLLALIIGFVDMRIDAHRLIWFNRKPIPIITNGIGIW 704

  Fly   552 QLAFELLSVMSLLSNCGLL---FLQPNVKDFFSHWLP-----SVPD--LSFVIFEHLLLGLKFLI 606
                  |.:::.|..|.:.   |:......|.|.:|.     :|.:  :..::|::|:.|||:|:
 Worm   705 ------LPILTFLQYCAVFTNAFIVAFTSGFCSTFLADGAYCTVQNRLIIVIVFQNLVFGLKYLL 763

  Fly   607 HKVIHERPRWVRIGLLKADFETSQALKQ 634
            ..||...|..:::.|.|..:..:..:::
 Worm   764 SSVIPSIPASIKLALRKKRYVVAHIVEK 791

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Axs	NP_476777.1	Anoctamin	202..623	CDD:282414	114/535 (21%)
anoh-1	NP_001255190.1	Anoct_dimer	36..270	CDD:292796	35/240 (15%)
		Anoctamin	273..782	CDD:282414	115/537 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1263362at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920