Protein Alignment Axs and ano5a

DIOPT Version :9

• Sequence 1: NP_476777.1
• Gene: Axs / 32645
• FlyBaseID: FBgn0000152
• Length: 646
• Species: Drosophila melanogaster
• Sequence 2: XP_021326432.1
• Gene: ano5a / 100534737
• ZFINID: ZDB-GENE-091013-2
• Length: 931
• Species: Danio rerio
• Alignment Length: 911
• Identity: 200/911 - (21%)
• Similarity: 325/911 - (35%)
• Gaps: 303/911 - (33%)

  Fly     1 MSEDAKSPGPRTRNI----------IENQLFRRQRSLKLEALQR----QRTLDS---NDGVEGLG 48
            ||..|.|.|......          :||....|:|:|.|:...|    |::.||   .|||.
Zfish    16 MSRTAWSSGEDNNGFHSNSDKETFQLENAEIWRKRALFLKYRSRVDKQQQSKDSVYFRDGVR--- 77

  Fly    49 ADTEPFDKTHIVIIFTEKAKLRHCQDVEKI----IQEFGIQTTLEIVGKTE--KYLYLSASVD-- 105
                   :...|:.:.:.......||..|:    :|:.|::...|...::|  |..:|...|.
Zfish    78 -------RIDFVLSYIDDKDGEKKQDRRKVFEANLQKAGLEVETEDKSESEDGKTYFLKIHVPWE 135

  Fly   106 --------------------------------TLLRLADAA---ELEKMTTTHSMQKFNHGCISD 135
                                            |..||.|..   |.:..|:|....|.:...|.|
Zfish   136 VLATYADVLKIKVPFKANDIPENKEIPMGWLFTPFRLPDHVMNPEPDFFTSTFDKSKIDFFLIED 200

  Fly   136 --FLLPGMGKEQILRY--CEIPVLIKDVIQDGIKSYVQKGYIEDMFPLHDILY----------LE 186
              .|.|...:.:|:.|  ..||...:|..:.|||..:..|.....|||||..|          .|
Zfish   201 KETLFPASTRNRIVYYLLSRIPYSTEDKDKKGIKRLLNNGTYTSAFPLHDCRYWTRSRDDNCESE 265

  Fly   187 RF----NW---NLKRTKLPIEDIRNYFGSSIGLYFGFIEFYTKALIFPSLFGILQYV-----FDL 239
            |:    ||   :....:.|:..||.|:|..||:||.::.|||:.|.:.::.|:|.::     ||.
Zfish   266 RYSLYKNWARFSSFYKEQPLNLIRKYYGEKIGIYFAWLGFYTEMLSYAAVVGLLCFIYGVATFDE 330

  Fly   240 NI-----------------------------SLVCS------------------FYVVWTTIFLE 257
            ||                             |..||                  |..:|.|:|||
Zfish   331 NIWSREICNETIGGQIVMCPLCDKKCGYWKLSTTCSSSWQSYLFDNAATVFFAIFMGIWVTLFLE 395

  Fly   258 LWKRKCAGYSYRWGTIEMSSLDKPRSAYTGQLKPDPITGKMTLHYPMRYTYLQMYCIS------- 315
            .|||:.|...|.|..::.....:..     ||:|: ...|.|.....|.|..|.:.:.
Zfish   396 FWKRRQARLEYEWDLVDFEEEQQQL-----QLRPE-YESKCTNRRLNRVTQEQEWVLDQTPADKA 454

  Fly   316 -------------YPVVLGCVVAAGWFALYQFQIEAEVLADFGPDSWL-----LYVPVIVQS--- 359
                         ..:::..::....:.|..|...|.::.| .|.:.|     |..|....|
Zfish   455 GRFVLCWTTVLLWISLIIASIIGVIAYRLAVFAAFASIMKD-SPTNKLEIVGNLITPQFATSVTA 518

  Fly   360 -----VLIAIFSWAYEKLATFLTNLENHRTRSQYDRHRVNKLMLFEIVNNFFSQFYIAFV----- 414
                 |:|.:.::.||::|..:|::|..:|..:|:.....|:.||:.||.:.|.||:||.
Zfish   519 SCINFVIIMVLNFLYERVAIKITDMEVPKTHVEYENKLTIKMFLFQFVNYYSSCFYVAFFKGKFV 583

  Fly   415 ---------------LHD--------LRQLKYQLMMQLLVFQLLCIAQEIGIPLLAVLRQKYAEF 456
                           |.:        |.:|..||::.::..|:....||..:|.|    :.:...
Zfish   584 GYPGNYAYMFGPWSGLRNEECEPGGCLIELTTQLVIVMVGKQVWGNIQEALVPWL----RNWWVS 644

  Fly   457 RHREVAEEKLRSISDLPRYEQSFYESGLDEYHSTYEDYLQVCIQFGFVVLFAAVAPFAAIGALLN 521
            |......|.|.|     |:||......|.:....|| ||::.|||||:.||.|..|.|.:.||:|
Zfish   645 RSARNHPESLYS-----RWEQDHDLQNLGQLGLFYE-YLEMVIQFGFITLFVASFPLAPLLALMN 703

  Fly   522 NVFAVHIDMWKLCNIFKRPFARRAKNIGAWQLAFELLSVMSLLSNCGLLFLQP------------ 574
            |:..|.:|.||....|:||.|.:|.:||||:....:::|.|:::|..::....
Zfish   704 NILEVRVDAWKFTTQFRRPVAAKAHSIGAWEEILNMIAVFSVVTNAFIVSFTSDMIPRLVYQYVH 768

  Fly   575 -------------------NVKDF-------------------------------------FSH- 582
                               |:.:|                                     ::|
Zfish   769 NTGNAASMSGYITHSLSIYNISEFPPENRPDDDENPDWFNAGNYTTCRYRDYRYPPGHEKQYTHN 833

  Fly   583 ---WLPSVPDLSF-VIFEHLLLGLKFLIHKVIHERPRWVRIGLLKA---------DFETSQALKQ 634
               |......|:| :|.||::..:||.:..:|.:.|..|:..:.:.         |:|..:...|
Zfish   834 MDFWHILAAKLAFIIIMEHVVFVVKFFVAWLIPDVPSDVKARVKRERYLIQEYLHDYEVEKLKNQ 898

  Fly   635 L 635
            |
Zfish   899 L 899

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Axs	NP_476777.1	Anoctamin	202..623	CDD:282414	135/606 (22%)
ano5a	XP_021326432.1	Anoct_dimer	78..285	CDD:318420	42/206 (20%)
		Anoctamin	288..879	CDD:309610	135/607 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1263362at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920