Protein Alignment Axs and ano3

DIOPT Version :9

• Sequence 1: NP_476777.1
• Gene: Axs / 32645
• FlyBaseID: FBgn0000152
• Length: 646
• Species: Drosophila melanogaster
• Sequence 2: XP_031756440.1
• Gene: ano3 / 100495805
• XenbaseID: XB-GENE-1012403
• Length: 983
• Species: Xenopus tropicalis
• Alignment Length: 794
• Identity: 177/794 - (22%)
• Similarity: 302/794 - (38%)
• Gaps: 236/794 - (29%)

  Fly    32 LQRQRTLDSNDGVEGLGADTEPFDKTHIV----IIFTEKAKLRHC--QDVEKIIQEFGIQTTLEI 90
            |:::.|.:.|...|||..:.|     |.:    |:|.:    .||  ..:.|..:...|:....
 Frog   175 LEKRSTFEKNLRAEGLMLERE-----HAITNNDIMFVK----IHCPWDTLCKYAERMNIRMPFR- 229

  Fly    91 VGKTEKYLYL---SASVDTLLR--------------------LADAAELEKMTTTHSMQKFNHGC 132
                :|..|.   |.::.:|.|                    |.|..|.:..|...|..:.:|..
 Frog   230 ----KKCYYTDWRSKTMGSLQRNMRQLKSWLPRNPMKLDKEALPDLEETDCYTAPFSRARMHHFT 290

  Fly   133 IS--DFLLPGMGKEQILRYCEIPVLIKDVIQD-----GIKSYVQKGYIEDMFPLHD--------- 181
            |:  |.......:.:|:.:    ||.:...:|     ||...:..|..|..||.|:
 Frog   291 INNKDTFFSNSTRSRIVHH----VLQRTKYEDGKSKMGISRLLSNGTYEAAFPPHEGSYKSRHPI 351

  Fly   182 ----------ILYLERFNWNLKRTKLPIEDIRNYFGSSIGLYFGFIEFYTKALIFPSLFGILQYV 236
                      :||.....|.:.....|::.||.|||..|||||.::.:||..||..:|.|:..::
 Frog   352 KTHGAQNHRHLLYERWARWGMWYKYQPLDLIRRYFGEKIGLYFAWLGWYTGMLIPAALVGLFVFL 416

  Fly   237 FDL---------------NISLVCS----------------------------------FYVVWT 252
            :.|               |.:::|.                                  |..:|.
 Frog   417 YGLFTMDSSQVSKEICEANETIMCPMCEKNCSLQRLNESCIYAKVTHLFDNGGTVFFAIFMAIWA 481

  Fly   253 TIFLELWKRKCAGYSYRWGTIEMSSLD---KPR--SAYTGQLKPDPITGKMTLHYPM--RYTYLQ 310
            |:|||.|||:.|..:|.|..|:....:   :|:  :.|:...:.:|||||.....|.  :.:.|
 Frog   482 TVFLEFWKRRRAVLTYDWDLIDWEDEEEELRPQFEAKYSQLERVNPITGKPEPFQPFSDKLSRL- 545

  Fly   311 MYCISYPVVLGCVVAAGWFALYQFQIEAEVLADFGPDSWLLY----------VPVIVQSVLIAIF 365
            |..:|....:..:|....||:..:::.|  :..|...:|...          ..|.:..::|...
 Frog   546 MVSVSGIFFMISLVLTAVFAVVVYRLVA--MEQFASFNWHFIKKYWQFATSGTGVCINFMIIMSL 608

  Fly   366 SWAYEKLATFLTNLENHRTRSQYDRHRVNKLMLFEIVNNFFSQFYIAFVLHDL--RQLKYQLMMQ 428
            :..|||:|..|||||:.||.|:::.....|:.||:.||...|.|||||.|...  |..||..:.|
 Frog   609 NVVYEKVAYLLTNLEHPRTDSEWENSFALKMFLFQFVNLNSSIFYIAFFLGRFAGRPGKYNRLFQ 673

  Fly   429 -----------------------LLVFQLLCIAQEIGIPLLAVLRQKYAEFRHREVAEEKLRSIS 470
                                   :::.|:.....|:|.|||    |.:...|..:.:.:.:.:..
 Frog   674 RWRLEECHPSGCLIDLCLQMGVIMVLKQMWNNFMELGYPLL----QNWWSRRKIKNSGQMVENKF 734

  Fly   471 DLPRYEQSFYESGLDEYHSTYEDYLQVCIQFGFVVLFAAVAPFAAIGALLNNVFAVHIDMWKLCN 535
            .||::|:.:....::. |...|:||::.|||||..:|.|..|.|.:.|||||:..:.:|.:|...
 Frog   735 TLPQWEKDWNLQPMNA-HGLMEEYLEMVIQFGFTTIFVAAFPLAPLLALLNNIIEIRLDAYKFVT 798

  Fly   536 IFKRPFARRAKNIGAWQLAFELLSVMSLLSNCGLLFLQ--------------PNVKDFFSH---- 582
            .::||...||.:||.|....|.:.|:::::|..::.:.              |.:.:.:.|
 Frog   799 QWRRPMPARATDIGIWYGILEGIGVLAVITNAFVIAITSDYIPRFVYAFKYGPCLDEGYRHEKCL 863

  Fly   583 ---------------------------------------------WLPSVPDLSFVI-FEHLLLG 601
                                                         |......|:|:| ||||:.|
 Frog   864 QGYVNSSLSIFDLKELGQGYSGYCRYRDYREPPWSSNPYEFTLQFWHVLAARLAFIIVFEHLVFG 928

  Fly   602 LKFLIHKVIHERPR 615
            :|..|..:|.:.|:
 Frog   929 IKSFIAYLIPDMPK 942

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Axs	NP_476777.1	Anoctamin	202..623	CDD:282414	135/569 (24%)
ano3	XP_031756440.1	Anoct_dimer	154..379	CDD:406563	41/221 (19%)
		Anoctamin	382..951	CDD:398306	135/569 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1263362at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920