Protein Alignment Axs and ano8

DIOPT Version :9

• Sequence 1: NP_476777.1
• Gene: Axs / 32645
• FlyBaseID: FBgn0000152
• Length: 646
• Species: Drosophila melanogaster
• Sequence 2: XP_004911073.1
• Gene: ano8 / 100491780
• XenbaseID: XB-GENE-6044545
• Length: 1121
• Species: Xenopus tropicalis
• Alignment Length: 881
• Identity: 192/881 - (21%)
• Similarity: 327/881 - (37%)
• Gaps: 329/881 - (37%)

  Fly    51 TEPFDKTHIVIIFTEKAK-------LRHCQ-DVEKIIQEF------GIQTTLEIVGKTEKYLYLS 101
            |.|.:...:|:.|::...       |.|.: .:.::|.:.      ||..           .:::
 Frog    56 TVPTENCDVVMTFSDNTDDHTLLWLLNHVRLGLPELIMQIRHHRHTGIYA-----------FFVT 109

  Fly   102 ASVDTLLRLADAAELEKMTTTHSMQKFNHG-----CISDFLLPGMGKE----------QILRYCE 151
            |:.:.|||.|:...|.|....    :|..|     |..|::...:..|          .|:||..
 Frog   110 ATYENLLRGAEEIGLRKPVKA----EFGGGTRVFSCEEDYIYQNIENELIFFTSQERQSIIRYWM 170

  Fly   152 IPVLIKD----------VIQDGIKSYVQKGYIEDMFPLHDILYLERFNWNLKRT-------KLPI 199
            ..:..|.          ..|..|.....:|.|:.:||:|:...|.|    |.|:       |.|:
 Frog   171 ENLRAKQGESLHNIHFLEGQPIIPELTARGVIQQVFPIHEQRILSR----LMRSWVQAICEKQPL 231

  Fly   200 EDIRNYFGSSIGLYFGFIEFYTKALIFPSLFGILQYVF--------DLNISLVCSFYVVWTTIFL 256
            ::|.:|||..:.:||.::.|||.:|::|::||::.::.        |:...:...|.|||.|:||
 Frog   232 DEICDYFGVKVAMYFSWMGFYTSSLVYPAVFGMMLWMITESDQTSRDICCVVFALFNVVWATLFL 296

  Fly   257 ELWKRKCAGYSYRWGTIEMSS--LDKPRSAYTGQLKPDPITGKMTLHYPMRYTYLQMYCISYPVV 319
            |.|||:.|..:|:|||::..:  :::||..:.|..:..|:|.....:||.....|....:|.||.
 Frog   297 EGWKRRGAELAYKWGTLDTPAEFIEEPRPQFRGVKRISPVTNCEEFYYPPWKRLLFQSFVSLPVC 361

  Fly   320 LGC-----VVAAGWFALYQFQIEAEVLADFGPDSWLLYVPVIVQSVLIAIFSWAYEKLATFLTNL 379
            :.|     ||....|.|.:|.:..:.|...     :.:.|.|:.:|:::.....|.|:|.:|.::
 Frog   362 VSCLCFVFVVMLACFELQEFILSIKELPRV-----VRFFPKILLAVIVSSCDEVYRKIAYWLNDM 421

  Fly   380 ENHRTRSQYDRHRVNKLMLFEIVNNFFSQFYIAFVLHDLRQLK---------------------- 422
            ||:|.:|.|::|.:.|::||:.||::.|.|||.|.|.|:.:||
 Frog   422 ENYRLQSAYEKHLIIKIVLFQFVNSYLSLFYIGFYLKDMERLKELFLVLSLPHSFTRQVKDALLP 486

  Fly   423 ---YQLMMQLLVFQLL-----CIAQEIGIPLLAVLR----------------------------- 450
               .|..:.|:|.:.|     |:.:...:..|.|:|
 Frog   487 FLSLQFHLFLIVLRALLRSAWCLFKSKMLATLLVIRQFLQNVKEVSQPHLYQKLQRGELTPRSVW 551

  Fly   451 -----------QKYAEFRH-----------------------------------REVAEEKLRSI 469
                       |||:..:|                                   .:..||:..||
 Frog   552 LFVRYALKRLFQKYSLPQHPLRTPGNPMETGAGGRKKCLNGGCGVPEEEEGVVSEDEEEEEEESI 616

  Fly   470 SD----------------------LPRYE------------------------------------ 476
            .|                      :|:.|
 Frog   617 MDCGLKLKRVSFLEKGERREDVGLVPQQEDEGAFLQEGSPTLMERGSDPASVFQLEDEEDEEQEG 681

  Fly   477 ----------------------------------------------------------------- 476
                                                                             
 Frog   682 ASGGVLQEGLEQESGVKLRQHRRRRKRVILEEEQSREDEEDDTEMKQKRESWIDPPEDNYPTKLS 746

  Fly   477 QSFYESGLDEYHSTYEDYLQVCIQFGFVVLFAAVAPFAAIGALLNNVFAVHIDMWKLCNIFKRPF 541
            |:..||.:.:|..|:.||.::.:|||:||||::..|.||:.||:||:..:..|.:|||...:|||
 Frog   747 QAEVESCMKKYEDTFNDYQEMFVQFGYVVLFSSAFPLAAVCALINNIIEIRSDAFKLCTGLQRPF 811

  Fly   542 ARRAKNIGAWQLAFELLSVMSLLSNCGLL-------FLQPNVKDFFSHWL-PSVPDLSFVIFEHL 598
            .||...||.||...|.:.|::::.||.|:       .|.|        || |....:..|:.||.
 Frog   812 GRRVDGIGQWQNVMEAMGVIAIIVNCYLMGQCGQLQRLLP--------WLGPETTIIFIVVLEHF 868

  Fly   599 LLGLKFLIHKVIHERPRWVRIGLLKADFETSQALKQ 634
            .|.||::||.||.:.|.||...:.|.:::..:|.|:
 Frog   869 ALLLKYIIHVVIPDIPGWVAEEMAKLEYQRREAFKK 904

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Axs	NP_476777.1	Anoctamin	202..623	CDD:282414	151/671 (23%)
ano8	XP_004911073.1	Anoctamin	234..>470	CDD:282414	75/240 (31%)
		Anoctamin	<760..895	CDD:282414	54/142 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1263362at2759
OrthoFinder	1	1.000	-	-		FOG0001419
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010