Protein Alignment Axs and LOC100490855

DIOPT Version :10

• Sequence 1: NP_476777.1
• Gene: Axs / 32645
• FlyBaseID: FBgn0000152
• Length: 646
• Species: Drosophila melanogaster
• Sequence 2: XP_031756610.1
• Gene: LOC100490855 / 100490855
• XenbaseID: XB-GENE-29080411
• Length: 798
• Species: Xenopus tropicalis
• Alignment Length: 784
• Identity: 159/784 - (20%)
• Similarity: 280/784 - (35%)
• Gaps: 268/784 - (34%)

  Fly    56 KTHIVIIFTEKA-KLRHCQDVEKIIQEFGIQTTLEIVGKTEKYLYLSASVDTLLRLADAAELEKM 119
            :.|.:.:..:|. |.:..:|.:  :..:|::...:|.   .||:.|..:.|     .....:|..
 Frog    62 RQHYISVLLKKGFKTKKVRDGK--VTFYGVRAPTDIF---HKYVRLLHNPD-----KGHTSIESP 116

  Fly   120 TTTHSMQKFNHGCISDFLLPGMGKEQILRYCEIPVLIKDVIQDGIKSYVQKGYIEDMFPLH---- 180
            .:..|..:..|..:.:..:...|||:.|             ||.||:.|    .|..||||
 Frog   117 VSPTSRIRIVHFILHNTAILFRGKEEKL-------------QDLIKTQV----FEAAFPLHTRKD 164

  Fly   181 --------------DILYLERFNWNLKRTKLPIEDIRNYFGSSIGLYFGFIEFYTKALIFPSLFG 231
                          ||:|::           |||:||.|:|..:.|||.::.:||..|::.::.|
 Frog   165 QTREGLKKKWARWRDIIYVQ-----------PIEEIRAYYGEKVALYFAWLGWYTIMLLYAAVVG 218

  Fly   232 IL---------------QYVFDLNISLVC----------------------------------SF 247
            ::               |.:...|.:|:|                                  .|
 Frog   219 LIVFFYGFVHFDNSQISQEICTANNTLMCPLCDQNCPYWPLSDTCTYAKVTHLFDNEGTVFFAMF 283

  Fly   248 YVVWTTIFLELWKRKCA----GYS-YRWGTIEMSSLDKPRSAYTGQLKPDP-ITGKMTLHYPMRY 306
            ..||.|:|||||||..|    |:: |.|        |:.......:|..|| .|.|...|
 Frog   284 MAVWATVFLELWKRARANTVSGWNLYNW--------DEDEEELALELINDPECTIKKHEH----- 335

  Fly   307 TYLQMYCISYPVVLG-CVVAAGWFALYQFQI--EAEVLADFGPDSW-----------------LL 351
                .|..|..|:|| .||.|....:.|..:  ...|...|...||                 |.
 Frog   336 ----SYWRSMAVLLGAAVVIAVLIGIAQALVIYRVVVTVSFMRSSWEFLREHANTAAVMSGAVLH 396

  Fly   352 YVPVIVQSVLIAIFSWAYEKLATFLTNLENHRTRSQYDRHRVNKLMLFEIVNNFFSQFYIAFVLH 416
            |:.:::.:.:..:       :|.:|.|||..||.::.:.....|:..|:.|.:|.|.||:||.|.
 Frog   397 YLTIVIMTKVNRV-------IAGYLCNLEKPRTFTERENSFTTKVFTFQFVTHFSSLFYVAFFLG 454

  Fly   417 DLR-------QLKYQLMMQLL--------VFQLLCIAQEIGIPLLAVLRQ----------KYAEF 456
            .:.       ::..|..::..        :|..:|:        :.||:|          .|..:
 Frog   455 RINGYPGNYVRIAGQWRLEECHPSGCITDLFIQMCV--------IMVLKQTLSNCVEYLSPYFSY 511

  Fly   457 RHREVAEEKLR------SISDLPRYEQSFYESGLDEYHSTYEDYLQVCIQFGFVVLFAAVAPFAA 515
            :.|.:.:.:.|      |........::.|..|.....|.::::|::.||:.|..:|.|..|.|.
 Frog   512 KWRLMKDRRCRVHGEDGSEDSAAECWRTNYRLGAVHVFSLFDEFLEMVIQYSFTTIFVAAFPLAP 576

  Fly   516 IGALLNNVFAVHIDMWKLCNIFKRPFARRAKNIGAWQLAFELLSVMSLLSNCGLLF--------- 571
            :.|.||||..:.:|..|:..:.:|...|:|.:||.|....|.:.|:::::| ||:.
 Frog   577 VLAFLNNVLEIRLDAIKMTRLQRRFVPRKANDIGIWLQVLEAVGVLAVITN-GLVIAVTSDFIPR 640

  Fly   572 ----------------------------------------------LQPNVKDFFSHWLPSVPDL 590
                                                          |..||.:.......|..|.
 Frog   641 LIYLYVYGPCANGTTEGINCLSGYVDSSLSVFYTKDFEDLTQVSRSLYTNVTECRYRDYRSAADY 705

  Fly   591 SF---------------VIFEHLLLGLKFLIHKVIHERPRWVRIGLLKADFETSQALKQLKKFKA 640
            ||               ::|||:.:.:||:....:.:.|:  |:.....|.:....|::|.....
 Frog   706 SFSTQFWHIFAARLGFLIVFEHVAVCIKFVAAWFVPDIPQ--RVENYNLDMKKQHLLEELSMMPE 768

  Fly   641 EANK 644
            |:::
 Frog   769 ESDE 772

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Axs	NP_476777.1	Anoctamin	202..623	CDD:461349	122/596 (20%)
LOC100490855	XP_031756610.1	Anoct_dimer	44..186	CDD:465044	30/161 (19%)
		Anoctamin	189..757	CDD:461349	123/602 (20%)