Protein Alignment Axs and ano5

DIOPT Version :9

• Sequence 1: NP_476777.1
• Gene: Axs / 32645
• FlyBaseID: FBgn0000152
• Length: 646
• Species: Drosophila melanogaster
• Sequence 2: XP_031756250.1
• Gene: ano5 / 100489787
• XenbaseID: XB-GENE-5952827
• Length: 928
• Species: Xenopus tropicalis
• Alignment Length: 834
• Identity: 177/834 - (21%)
• Similarity: 308/834 - (36%)
• Gaps: 262/834 - (31%)

  Fly    33 QRQRTLDSNDGVEGLGADTEP----------FDKTH----IVIIFTEKAKLRH-------CQDVE 76
            :|:|..:.|....||..:||.          |.|.|    ::..:.|...|:.       ..|.|
 Frog   112 ERRREFELNLQKSGLELETEDKKESENGKTYFVKIHAPWEVLTTYAEVLNLKMPLKADDLKDDSE 176

  Fly    77 KIIQEFGIQTTLEIVGKTEKYLYLSASVDTLLRLADAAELEKMTTTHSMQKF----NHGCISDFL 137
            .|:..     .|::....::.:|......|.....|..||.:   |...:||    ....|..::
 Frog   177 NILSH-----VLKLFKLPQEVMYPEPDYFTAPFRKDKQELFR---TEEREKFFTPSTRNRIVYYI 233

  Fly   138 LPGM------GKEQILRYCEIPVLIKDVIQDGIKSYVQKGYIEDMFPLHDILY--------LERF 188
            |...      ||::.                |||..:..|...|.:||||..|        .||:
 Frog   234 LSRCHYGEEEGKKKF----------------GIKRLLTNGSYLDAYPLHDCQYWKKTDERNCERY 282

  Fly   189 ----NWNLKRTKL----PIEDIRNYFGSSIGLYFGFIEFYTKALIFPSLFGILQYVF-------- 237
                :| .|.|:.    |::.||.|:|..||:||.::.|||:.|.:.::.|...:::
 Frog   283 TLYTHW-AKFTRFYKEQPLDLIRKYYGEKIGIYFAWLGFYTEMLFYAAVVGFFCFLYGWITMDDS 346

  Fly   238 -------DLNIS---LVCS----------------------------------FYVVWTTIFLEL 258
                   |.||.   ::|.                                  |..:|.|:|||.
 Frog   347 ISSKEICDPNIGGQIIMCPLCDKRCEFWRLNSTCEPSQYSHMFDNVATLFFAIFMGIWVTLFLEF 411

  Fly   259 WKRKCAGYSYRWGTIEMSSLDKP---RSAYTG---QLKPDPITGKMTL-------HYPMRYTYLQ 310
            |||:.|...|.|..::.....:.   |..|..   :.|.:|:|.:..|       ::..:..:..
 Frog   412 WKRRQARLEYEWDLVDFEEEQQQLQLRPEYESKCTEKKKNPVTQENELVIKQTACNFLAKMFWCW 476

  Fly   311 MYCISY-PVVLGCVVAAGWFALYQFQIEAEVLADFGPDSWLLYVPV---------------IVQS 359
            |..:.: .:::..::|...:.|:.:...|.::     |:.|...||               ::..
 Frog   477 MSVLFWIALIIASIIAIIVYRLWVYAAFASIM-----DNNLALKPVSNLLTPQLATSVTASVLNF 536

  Fly   360 VLIAIFSWAYEKLATFLTNLENHRTRSQYDRHRVNKLMLFEIVNNFFSQFYIAFVLHD------- 417
            |.|.|.::.||::|.::|::|..||..:|:.....|:.||:.||.:.|.||:||....
 Frog   537 VTIMILNFLYERVAIWITDMEIPRTHLEYENRLTMKMFLFQFVNYYSSCFYVAFFKGKFVGYPAD 601

  Fly   418 ------------------LRQLKYQLMMQLLVFQLLCIAQEIGIPLLAVLRQKYAEFRHREVAEE 464
                              |.:|..||.:.:...|:....||..:|......::.....|.:....
 Frog   602 YSYLFGKWRNEECDPAGCLIELTTQLTIVMAGKQIWGNIQEAFVPWTWNWLKRRKARNHPQNLYS 666

  Fly   465 KLRSISDLPRYEQSFYESGLDEYHSTYEDYLQVCIQFGFVVLFAAVAPFAAIGALLNNVFAVHID 529
            :.....||    |:|...||      :.:||::.:||||:.||.|..|.|.:.|||||:..:.:|
 Frog   667 RWEHDGDL----QTFGGLGL------FNEYLEMVVQFGFITLFVASFPLAPLLALLNNILEIRVD 721

  Fly   530 MWKLCNIFKRPFARRAKNIGAWQLAFELLSVMSLLSNCGLLFLQP-------------------- 574
            .|||...||||.|.:|.:||.||.....::::|:::|..::....
 Frog   722 SWKLTTQFKRPVAAKAHSIGVWQEILNGIAILSVVTNAFIVAFTSDMIPRLVYYYAYSQDEGTPM 786

  Fly   575 -----------NVKDFFSHWLPSVPDLS-----------------------------------FV 593
                       ||.||....:|...|::                                   .:
 Frog   787 SGYIGSSLSVFNVSDFKEQSMPMENDMNVISCRYRDYRYPPGHEKEYQVTMQYWHILAAKMAFII 851

  Fly   594 IFEHLLLGLKFLIHKVIHERPRWVRIGLLKADFETSQALK--QLKKFKAE-ANK 644
            |.||::..:||.:..:|.:.|..|:..:.:..|.|.:.|.  :|:|.|.: .||
 Frog   852 IMEHVVFLVKFFVAWLIPDVPSEVKARVKREKFLTQKILHEYELEKLKQKLCNK 905

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Axs	NP_476777.1	Anoctamin	202..623	CDD:282414	125/592 (21%)
ano5	XP_031756250.1	Anoct_dimer	85..300	CDD:406563	43/212 (20%)
		Anoctamin	303..882	CDD:398306	125/593 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1263362at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010