Protein Alignment Axs and LOC100489387

DIOPT Version :10

• Sequence 1: NP_476777.1
• Gene: Axs / 32645
• FlyBaseID: FBgn0000152
• Length: 646
• Species: Drosophila melanogaster
• Sequence 2: XP_031756607.1
• Gene: LOC100489387 / 100489387
• XenbaseID: XB-GENE-29079691
• Length: 730
• Species: Xenopus tropicalis
• Alignment Length: 759
• Identity: 151/759 - (19%)
• Similarity: 266/759 - (35%)
• Gaps: 269/759 - (35%)

  Fly    56 KTHIVIIFTEKA-KLRHCQDVEKIIQEFGIQTTLEIVGKTEKYLYLSASVDTLLRLADAAELEKM 119
            :.|.:.:..:|. |.:..:|.:  :..:|::...:|.   .||:.|..:.|     .....:|..
 Frog    45 RQHYISVLLKKGFKTKKVRDGK--VTFYGVRAPTDIF---HKYVRLLHNPD-----KGHTSIESP 99

  Fly   120 TTTHSMQKFNHGCISDFLLPGMGKEQILRYCEIPVLIKDVIQDGIKSYVQKGYIEDMFPLH---- 180
            .:..|..:..|..:.:..:...|||:.|             ||.||:.|    .|..||||
 Frog   100 VSPTSRIRIVHFILHNTAILFRGKEEKL-------------QDLIKTQV----FEAAFPLHTRKD 147

  Fly   181 --------------DILYLERFNWNLKRTKLPIEDIRNYFGSSIGLYFGFIEFYTKALIFPSLFG 231
                          ||:|::           |||:||.|:|..:.|||.::.:||..|::.::.|
 Frog   148 QTREGLKKKWARWRDIIYVQ-----------PIEEIRAYYGEKVALYFAWLGWYTIMLLYAAVVG 201

  Fly   232 ILQYVFDL---------------NISLVC----------------------------------SF 247
            ::.:.:..               |.:|:|                                  .|
 Frog   202 LIVFFYGFVHFDNSQISQEICRANNTLMCPLCDQNCPYWPLSDTCTYAKVTHLFDNEGTVFFAMF 266

  Fly   248 YVVWTTIFLELWKRKCA----GYS-YRWGTIEMSSLDKPRSAYTGQLKPDP-ITGKMTLHYPMRY 306
            ..||.|:|||||||..|    |:: |.|        |:.......:|..|| .|.|...|...|:
 Frog   267 MAVWATVFLELWKRARANTVSGWNLYNW--------DEDEEELALELINDPECTIKKHEHSYWRF 323

  Fly   307 TYLQMYCISYPVVLG-CVVAAGWFALYQFQI--EAEVLADFGPDSW-----------------LL 351
                     ..|:|| .||.|....:.|..:  ...|...|...||                 |.
 Frog   324 ---------MAVLLGAAVVIAVLIGIAQALVIYRVVVTVSFMRSSWEFLREHANTAAVMSGAVLH 379

  Fly   352 YVPVIVQSVLIAIFSWAYEKLATFLTNLENHRTRSQYDRHRVNKLMLFEIVNNFFSQFYIAFVLH 416
            |:.:::.:.:..:       :|.:|.|||..||.::.:.....|:..|:.|.:|.|.||:||
 Frog   380 YLTIVIMTKVNRV-------IAGYLCNLEKPRTFTERENSFTTKVFTFQFVTHFSSLFYVAF--- 434

  Fly   417 DLRQLKYQLMMQLLVFQLLCIAQEIGIPLLAVLRQKYAEFRHREVAEEKLR------SISDLPRY 475
                                           .|.::|..::.|.:.:.:.|      |.......
 Frog   435 -------------------------------FLGRRYFSYKWRLMKDRRCRVHGEDGSEDSAAEC 468

  Fly   476 EQSFYESGLDEYHSTYEDYLQVCIQFGFVVLFAAVAPFAAIGALLNNVFAVHIDMWKLCNIFKRP 540
            .::.|..|.....|.::::|::.||:.|..:|.|..|.|.:.|.||||..:.:|..|:..:.:|.
 Frog   469 WRTNYRLGAVHVFSLFDEFLEMVIQYSFTTIFVAAFPLAPVLAFLNNVLEIRLDAIKMTRLQRRF 533

  Fly   541 FARRAKNIGAWQLAFELLSVMSLLSNCGLLF---------------------------------- 571
            ..|:|.:||.|....|.:.|:::::| ||:.
 Frog   534 VPRKANDIGIWLQVLEAVGVLAVITN-GLVIAVTSDFIPRLIYLYVYGPCANGNTEGINCLSGYV 597

  Fly   572 ---------------------LQPNVKDFFSHWLPSVPDLSF---------------VIFEHLLL 600
                                 |..||.:.......|..|.||               ::|||:.:
 Frog   598 DSSLSVFYTKDFEDLTQVSRSLYTNVTECRYRDYRSAADYSFSTQFWHIFAARLGFLIVFEHVAV 662

  Fly   601 GLKFLIHKVIHERPRWVRIGLLKADFETSQALKQLKKFKAEANK 644
            .:||:....:.:.|:  |:.....|.:....|::|.....|:::
 Frog   663 CIKFVAAWFVPDIPQ--RVENYNLDMKKQHLLEELSMMPEESDE 704

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Axs	NP_476777.1	Anoctamin	202..623	CDD:461349	114/571 (20%)
LOC100489387	XP_031756607.1	Anoct_dimer	27..169	CDD:465044	30/161 (19%)
		Anoctamin	172..689	CDD:461349	115/577 (20%)