Protein Alignment Axs and ano10

DIOPT Version :9

• Sequence 1: NP_476777.1
• Gene: Axs / 32645
• FlyBaseID: FBgn0000152
• Length: 646
• Species: Drosophila melanogaster
• Sequence 2: XP_002937896.1
• Gene: ano10 / 100487513
• XenbaseID: XB-GENE-955754
• Length: 651
• Species: Xenopus tropicalis
• Alignment Length: 645
• Identity: 208/645 - (32%)
• Similarity: 337/645 - (52%)
• Gaps: 78/645 - (12%)

  Fly    59 IVIIFTEKAK-------LRHCQDVEKIIQEFGIQTTLE--IVGKTEKYLY-LSASVDTLLRLADA 113
            :||...:.||       ::..:|.:|   :.|.|..::  ::...|:|:| :..|...||..|::
 Frog    19 VVIELAKDAKEETREWLVKKIRDKKK---DGGTQLLIKPLVISNDEEYIYVVGGSTKRLLLGAES 80

  Fly   114 AELEKMTTTHSMQKF---NHGCISDFLLPGMGKEQILRYCEIPVLIKDVIQDGIKSYVQK----- 170
            ..:.|.....||:.|   |.....|:...|   |..|...:...:||..: |.:::..:|
 Frog    81 VGMVKECIDGSMKPFIYSNRKEYKDWTEDG---ENFLSMADCQYIIKYEL-DNLRAQDEKNIPGY 141

  Fly   171 ------------------GYIEDMFPLHDILYLERF--NWNLKRTKL---PIEDIRNYFGSSIGL 212
                              |.:..:|||||...|:|.  .|.| |.||   ||:.|::|||.::||
 Frog   142 PNSKLYPGKSIFRRLKTSGIMIQVFPLHDKEELKRLRHQWYL-RIKLAFQPIDQIQHYFGDTLGL 205

  Fly   213 YFGFIEFYTKALIFPSLFGILQYVFDL----NISLVCSFYVVWTTIFLELWKRKCAGYSYRWGTI 273
            ||.|:|::|.|||..:|.||..|.||.    ...:..:|.:||:|:.||:|||..:..:||||::
 Frog   206 YFAFLEYFTMALIPMALIGIPYYFFDWEDYDKYVIFATFNLVWSTVILEVWKRLSSAMTYRWGSL 270

  Fly   274 EMS-SLDKPRSAYTGQLKPDPITGKMTLHYPMRYTYLQMYCISYPVVLGCVVAAGWFALYQFQIE 337
            .|. ..::||..:.|.|..:|:||:....|......|::|.:|.|.|..|:..|.:..:..|.:|
 Frog   271 IMKRKFEEPRPGFHGVLGINPVTGRKEPIYSSFKRQLRIYLVSVPFVCVCLYLAIYVMMIYFDLE 335

  Fly   338 AEVLA-------DFGPDSWLLYVPVIVQSVLIAIFSWAYEKLATFLTNLENHRTRSQYDRHRVNK 395
            ...||       .|  .:.|||||.|:.:|:|.|.:..|:..|.|||:.||||..|.|..|.|.|
 Frog   336 HWALAYHQEQQSTF--SNLLLYVPSIIYAVVIEILNRIYKIAAEFLTSWENHRLESSYQNHLVLK 398

  Fly   396 LMLFEIVNNFFSQFYIAFVLHDLRQLKYQLMMQLLVFQLLCIAQEIGIPLLAVLRQKYAEFRHRE 460
            :::|.|||.|.|.||||||:.|::.|:..|...|:..|:|....|..:|.       :.:.|...
 Frog   399 VLVFNIVNCFASLFYIAFVMCDMKLLRQSLATLLITSQILNQFVEALLPY-------WLQKRSSR 456

  Fly   461 VAEEKLRSI---SDLPRYEQSFYESGLDEYHSTYEDYLQVCIQFGFVVLFAAVAPFAAIGALLNN 522
            ..::|::|:   :|....||...|..:|.|..|::|||::.:.||:|.||:.|.|.|||.|:|||
 Frog   457 KIKKKVKSLNVDTDYTLLEQIHLEKDMDTYLGTFDDYLELFLLFGYVSLFSCVYPLAAIFAVLNN 521

  Fly   523 VFAVHIDMWKLCNIFKRPFARRAKNIGAWQLAFELLSVMSLLSNCGLLFLQPNVKDFFSHWLPSV 587
            :..::.|..|:|.::||||::.:.|||.|.||||.:.::::::||.||.:...|...|.   .|.
 Frog   522 LTEMYSDALKMCRVYKRPFSQPSANIGVWMLAFETMGIIAVVTNCTLLGMSSQVSTLFQ---DSK 583

  Fly   588 PDLSFVI--FEHLLLGLKFLIHKVIHERPRWVRIGLLKADFETSQALKQLKKFKAEANKM 645
            .||...:  .||.||.|||::..||.::|..:::.|.:.:||:.:|||:.::.|..:..:
 Frog   584 RDLILTVAAIEHALLALKFILAFVIPDKPYDIQVKLARLEFESMEALKKNQQMKLSSESL 643

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Axs	NP_476777.1	Anoctamin	202..623	CDD:282414	159/437 (36%)
ano10	XP_002937896.1	Anoctamin	195..621	CDD:367984	159/437 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	268	1.000	Domainoid score	I1830
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H14314
Inparanoid	1	1.050	297	1.000	Inparanoid score	I2672
OMA	1	1.010	-	-		QHG57839
OrthoDB	1	1.010	-	-		D1263362at2759
OrthoFinder	1	1.000	-	-		FOG0001419
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR12308
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X4482
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	10.080