Protein Alignment Nemp and nemp1

DIOPT Version :10

• Sequence 1: NP_573142.1
• Gene: Nemp / 32639
• FlyBaseID: FBgn0030768
• Length: 454
• Species: Drosophila melanogaster
• Sequence 2: NP_001034832.1
• Gene: nemp1 / 594887
• XenbaseID: XB-GENE-974573
• Length: 431
• Species: Xenopus tropicalis
• Alignment Length: 340
• Identity: 106/340 - (31%)
• Similarity: 170/340 - (50%)
• Gaps: 54/340 - (15%)

  Fly    82 YGGKTPEEVLQHYKDKQSLFSITLFAQKRQLLQLSPFEQQCIGISSRQAYTVILNSIPLDLWRLA 146
            |..||..:|  |..|..:.:|:.|..                |...|..:.
 Frog   124 YNNKTCIKV--HVSDTDTYYSVALSR----------------GFDPRLFFV-------------- 156

  Fly   147 QFAVGILILFSARRLAKNSVFYYLVGIVIGICASLLVVIYLAAKLFPRRTMMYGVLIGGWTIGFY 211
             |..|:|:.|....|:::.:|||..||.:|:.||:|:::::.:||.|:::....:|:|||::..|
 Frog   157 -FLCGLLLFFYGDTLSRSQIFYYSTGITVGMLASMLILVFMLSKLMPKKSPFVALLLGGWSVSIY 220

  Fly   212 VIKQLADNLRLILITYRDHVLGYLVITGLISFLICYRIGPPKNPRSQTIVMWVLQAIGAVMAYFS 276
            ||:.:..||:.|...|..::||||.|.|.:||..||:.||.:|.||..|:.|.||.||.::.|.|
 Frog   221 VIQLVFKNLQAICTEYWQYLLGYLGIVGFVSFAFCYKYGPLENERSINILNWTLQLIGLLLMYIS 285

  Fly   277 SWHTSAVIFIMVLVFVAHY--FPISWTNQIKFMYRRRFPLKR------RMLTQEEYEQQTAVETS 333
            .......:.::|:.|....  :|:.|   |..:| |:..|||      |:||:|||.:|..|||.
 Frog   286 VQIRHIAVTMVVIAFCTKQIEYPVRW---IYILY-RKIKLKRGKPSPPRLLTEEEYRKQGDVETR 346

  Fly   334 KSLADLRKYVNSPECKQWAVMGKLRDPLRFASFANGAPHLDDEEIEDHSRT-------IEESMDA 391
            |:|.:||.|.:||:...|..:.:::.|.|||.|..|:.||...|:..|...       :|:.:..
 Frog   347 KALEELRGYCSSPDFAAWKTVSRIQSPKRFADFVEGSSHLTPNEVSVHEHEYGFGGSFLEDELFG 411

  Fly   392 APEEESVEEPEEDKP 406
              |:..|||..|.:|
 Frog   412 --EDSDVEEEMEIEP 424

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nemp	NP_573142.1	NEMP	132..375	CDD:463008	87/250 (35%)
nemp1	NP_001034832.1	NEMP	147..388	CDD:463008	89/275 (32%)
		A, required for its colocalization with lamins at the nuclear envelope. /evidence=ECO:0000250|UniProtKB:B9X187	176..287		46/110 (42%)
		Nuclear localization signal. /evidence=ECO:0000250|UniProtKB:B9X187	317..325		4/7 (57%)
		Interaction with banf1-a and banf1-b. /evidence=ECO:0000250|UniProtKB:B9X187	326..431		35/101 (35%)
		B, required for interaction with ran. /evidence=ECO:0000250|UniProtKB:B9X187	326..395		27/68 (40%)
		BAF-binding site (BBS), essential for interaction with banf1-a, banf1-b and ran. /evidence=ECO:0000250|UniProtKB:B9X187	368..375		1/6 (17%)