Protein Alignment mthl1 and GCR1

DIOPT Version :10

• Sequence 1: NP_573140.1
• Gene: mthl1 / 32637
• FlyBaseID: FBgn0030766
• Length: 676
• Species: Drosophila melanogaster
• Sequence 2: NP_175261.1
• Gene: GCR1 / 841247
• AraportID: AT1G48270
• Length: 326
• Species: Arabidopsis thaliana
• Alignment Length: 340
• Identity: 74/340 - (21%)
• Similarity: 123/340 - (36%)
• Gaps: 107/340 - (31%)

  Fly   306 AGAGIHDGSIGGTIEQANGQNLQKAVLTGGILVSIVFLSATLVAGFLLPAVHHALHWRCQICYVT 370
            ||.|:          .|..:::..|:.||...:|.|. ||.:|                 :||
plant     7 AGGGL----------TAGDRSIITAINTGASSLSFVG-SAFIV-----------------LCY-- 41

  Fly   371 CLLFGKI---------LLAIEELSSSL-----QPGSA-ACHTLAITMQFFFLAAFFWLNTMCFNI 420
            | ||.::         .||:.::..|.     .|... .|:....|..||.:|:|.|..|:.|.:
plant    42 C-LFKELRKFSFKLVFYLALSDMLCSFFLIVGDPSKGFICYAQGYTTHFFCVASFLWTTTIAFTL 105

  Fly   421 WWTFRDFRPSSLERNQEALRRYLYSLYAWGGPLLITFVAACVDQLPETTLLRPGFGQ------LY 479
            ..|....: :.:| :.||    ::.||.||..|::|.:.:              ||.      .:
plant   106 HRTVVKHK-TDVE-DLEA----MFHLYVWGTSLVVTVIRS--------------FGNNHSHLGPW 150

  Fly   480 CWFDN--RNLSI-FAYFYGPI-GLLLCANIALF-----VSTTHQLTCGLWKR-DDVKSSSEKSAL 534
            ||...  :..:: |..||.|: |.:|......|     :....::..|:..| |...:.:|...|
plant   151 CWTQTGLKGKAVHFLTFYAPLWGAILYNGFTYFQVIRMLRNARRMAVGMSDRVDQFDNRAELKVL 215

  Fly   535 GRVCLKLVVVMGVTWIADILSWLVG----------GPHGVWFFTDL---INALQGVFIFIVVGCQ 586
            .|.....::::|        ||..|          ..|.:::.:.|   ..||.|:|..|..|..
plant   216 NRWGYYPLILIG--------SWAFGTINRIHDFIEPGHKIFWLSVLDVGTAALMGLFNSIAYGFN 272

  Fly   587 PQVWTACRRIFCPRL 601
            ..|    ||....||
plant   273 SSV----RRAIHERL 283

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mthl1	NP_573140.1	7tmB3_Methuselah-like	326..598	CDD:410632	68/315 (22%)
		TM helix 1	327..352	CDD:410632	8/24 (33%)
		TM helix 2	362..384	CDD:410632	7/30 (23%)
		TM helix 3	396..423	CDD:410632	8/26 (31%)
		TM helix 4	441..461	CDD:410632	6/19 (32%)
		TM helix 5	485..515	CDD:410632	7/36 (19%)
		TM helix 6	530..557	CDD:410632	5/26 (19%)
		TM helix 7	562..587	CDD:410632	8/27 (30%)
GCR1	NP_175261.1	7tm_GPCRs	26..272	CDD:475119	62/294 (21%)
		TM helix 2	48..69	CDD:410628	3/20 (15%)
		TM helix 3	81..103	CDD:410628	7/21 (33%)
		TM helix 4	122..138	CDD:410628	6/15 (40%)
		TM helix 6	205..237	CDD:410628	7/39 (18%)
		TM helix 7	248..272	CDD:410628	7/23 (30%)