Protein Alignment mthl1 and Adgrd1

DIOPT Version :9

• Sequence 1: NP_001285340.1
• Gene: mthl1 / 32637
• FlyBaseID: FBgn0030766
• Length: 676
• Species: Drosophila melanogaster
• Sequence 2: XP_001070157.3
• Gene: Adgrd1 / 689257
• RGDID: 1594795
• Length: 903
• Species: Rattus norvegicus
• Alignment Length: 714
• Identity: 150/714 - (21%)
• Similarity: 257/714 - (35%)
• Gaps: 225/714 - (31%)

  Fly    48 PPRPSPPPTVKLNKCCHSGEYLNDGTCIAGSEALWLPMVYLVQQQRFFEPHGASPRFLK----FL 108
            ||..|.||.:   ...|.         :..::|....:..|.::::.|:......|:|:    .|
  Rat   284 PPLSSTPPAM---PTAHP---------VMPTDAYHPIITNLTEERKHFQRPRTVLRYLQNVSLSL 336

  Fly   109 PNTRPTCRKDQT----TEIFRSRGANVMLFP--------------------------NGTLYVRE 143
            ||   ....::|    ||.|......|:|.|                          :..|..||
  Rat   337 PN---KSLSEETALNLTETFLRTVGEVLLLPSWIHVSEDNAVTLGLVDTIDTVMGHISSNLQPRE 398

  Fly   144 RALMVQPSDYCVDWEVAVVCLNDSQPINALEDPDY--AANPLVQQEPPKASLRLSKCCGKWGS-- 204
            ..:.:..|....::.||.|.    .|  ||..|.|  .|:.....|.|:.:|...    .|.:
  Rat   399 PHISLTGSSSMAEFSVAKVL----PP--ALSAPHYRFPAHGHSYIEIPREALHSQ----AWTTIV 453

  Fly   205 ---YNTQ---LQNCDLQPNHQAAVDGLLRLSPQLPEGSYQTSYGLPDCGQPGGYSIAGDWQDAKL 263
               |:|.   |.|  :.|           .|.::||                    |.:.:|..|
  Rat   454 GLLYHTMHYYLNN--IPP-----------ASTEIPE--------------------AANCRDCLL 485

  Fly   264 DRNTAMLQLP-------HKNLSAGQYCLEH-----TQR-------EGEVKIIACQHL-FS----- 303
            ...:.::.|.       .:|||.......|     ||:       |.....:.|..| ||
  Rat   486 SVASHLISLEVSPPPTLSQNLSGSPLITVHLRHKLTQKQYVDATNESNRLFLYCAFLNFSSGEGV 550

  Fly   304 -SAAGAGIHDGSIGGTI----EQANGQNLQKAV---LT------------GGILVSIVFLSATLV 348
             |:.|..:.:|::..::    ...|...|.:.|   ||            .|..:|::.|:||||
  Rat   551 WSSQGCALTEGNLTYSVCHCTHLTNFAILMQVVPLKLTLGHQVALSSISYVGCSLSVLCLAATLV 615

  Fly   349 AGFLLPAV----HHALHWRCQICYVTCLLFGKILLAIEELSSSLQPGSAACHTLAITMQFFFLAA 409
            ...:|.:|    :...|....:.:  .:|..::||.|   |.|::||:..|..||:.:.:|||.|
  Rat   616 TFAVLSSVSTIRNQRYHIHANLSF--AVLVAQVLLLI---SFSMEPGTVPCQVLAVLLHYFFLTA 675

  Fly   410 FFW-------LNTMCFNIWWTFRDFRPSSLERNQEALRRYLYSLYAWGGPLLITFVAACVDQLPE 467
            |.|       |.:|...::            .::::...|.|.: .||.||||..::.      .
  Rat   676 FAWMLVEGLHLYSMVIKVF------------GSEDSKHLYYYGI-GWGCPLLICIISV------S 721

  Fly   468 TTLLRPGFGQLYCWFDNRNLSIFAYFYGPIGLLLCANIALFVSTT----HQLTCGLWKRDDVKSS 528
            :::...|.|. .||....:.:|:| |.||..|::..||.:.|:.|    |..|      |..|..
  Rat   722 SSMDSYGTGD-SCWLSVESGAIWA-FVGPALLVIVVNIVILVAVTRVISHIST------DSYKIH 778

  Fly   529 SEKSAL---GRVCLKLVVVMGVTWIADILSWLVGGPHGVW-FFTDLINALQGVFIFIVVGCQPQV 589
            .:.||.   .:....|:.::|.:|:..:|:  |.....|: :...::|:.||:|||
  Rat   779 GDPSAFKLTAKAVAVLLPILGTSWVFGVLA--VSDRALVFQYMFAILNSSQGLFIF--------- 832

  Fly   590 WTACRRIFCPRLRHDITNT--TNGVQHSSSSQGLPSMAGGTEITQNTTTTT---TTTNTTATHM 648
                       |.|.:.|:  ....:|......|.|.:..|..|:.:::.|   |...|.:|.:
  Rat   833 -----------LFHCLLNSEVRAAFKHKMKVWSLTSSSAHTANTKPSSSDTVNGTRPGTASTKL 885

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mthl1	NP_001285340.1	7tm_4	329..579	CDD:304433	69/283 (24%)
Adgrd1	XP_001070157.3	LamG	<173..273	CDD:304605
		GPS	539..579	CDD:280071	8/39 (21%)
		7tm_4	595..831	CDD:304433	66/269 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4193
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810