Protein Alignment mthl1 and ADGRL4

DIOPT Version :9

• Sequence 1: NP_001285340.1
• Gene: mthl1 / 32637
• FlyBaseID: FBgn0030766
• Length: 676
• Species: Drosophila melanogaster
• Sequence 2: NP_071442.2
• Gene: ADGRL4 / 64123
• HGNCID: 20822
• Length: 690
• Species: Homo sapiens
• Alignment Length: 316
• Identity: 74/316 - (23%)
• Similarity: 121/316 - (38%)
• Gaps: 88/316 - (27%)

  Fly   298 CQH------LFSSAAGAGIHDGSIGGTIEQANGQNLQKAVLTGGILVSIVFLSATLVAGFLL--- 353
            |.|      |.||....||.|.:|...|.|.            ||::|::.|:..:...:..
Human   403 CNHLTHFAILMSSGPSIGIKDYNILTRITQL------------GIIISLICLAICIFTFWFFSEI 455

  Fly   354 ----PAVHHALHWRCQICYVTCLLFGKILLAIEELSSSLQPGSAACHTLAITMQFFFLAAFFWLN 414
                ..:|..|   |...::..|:|   |:.|...::.|     .|..:|..:.:||||||.|
Human   456 QSTRTTIHKNL---CCSLFLAELVF---LVGINTNTNKL-----FCSIIAGLLHYFFLAAFAW-- 507

  Fly   415 TMCFNIWWTFRDFRPSSLERNQEALRRYL---------------YSLYAWGGP-LLITFVAACVD 463
             ||.                  |.:..||               :.::.:..| :::.|.||...
Human   508 -MCI------------------EGIHLYLIVVGVIYNKGFLHKNFYIFGYLSPAVVVGFSAALGY 553

  Fly   464 QLPETTLLRPGFGQLYCWFDNRNLSIFAYFYGPIGLLLCANIALF---VSTTHQLTCGLWKRDDV 525
            :...||.:        ||....|..|:: |.||..|::..|:..|   :....:.|.||  :.:|
Human   554 RYYGTTKV--------CWLSTENNFIWS-FIGPACLIILVNLLAFGVIIYKVFRHTAGL--KPEV 607

  Fly   526 KSSSEKSALGRVCLKLVVVMGVTWIADILSWLVGGPHGVWFFTDLINALQGVFIFI 581
            .......:..|..|.|:.::|.|||..:|..:.......:.|| :.||.||:|||:
Human   608 SCFENIRSCARGALALLFLLGTTWIFGVLHVVHASVVTAYLFT-VSNAFQGMFIFL 662

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mthl1	NP_001285340.1	7tm_4	329..579	CDD:304433	60/275 (22%)
ADGRL4	NP_071442.2	EGF_CA	58..>91	CDD:284955
		GAIN	139..330	CDD:293098
		GPS	368..412	CDD:280071	2/8 (25%)
		7tm_4	424..660	CDD:304433	63/291 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4193
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810