Protein Alignment mthl1 and ADGRG6

DIOPT Version :9

• Sequence 1: NP_001285340.1
• Gene: mthl1 / 32637
• FlyBaseID: FBgn0030766
• Length: 676
• Species: Drosophila melanogaster
• Sequence 2: XP_006715579.1
• Gene: ADGRG6 / 57211
• HGNCID: 13841
• Length: 1251
• Species: Homo sapiens
• Alignment Length: 455
• Identity: 102/455 - (22%)
• Similarity: 180/455 - (39%)
• Gaps: 88/455 - (19%)

  Fly   274 HKNLSAGQY----CLEHTQREGEVKIIACQHLFSSAAGAGIHDG---SIGGTIEQANGQNLQKAV 331
            :||.|.|.:    |:.|...:....:..|.|.        .|.|   .:..:..|.:.:|.:  |
Human   810 NKNKSFGGWNTSGCVAHRDSDASETVCLCNHF--------THFGVLMDLPRSASQLDARNTK--V 864

  Fly   332 LTG----GILVSIVFLSATLVAGFLLPAVHHALHWRCQICYVTCLLFGKILLAIEELSSSLQPGS 392
            ||.    |..:|.:|.:|||:.......:......:..:...|.|||..:|..::...:|... .
Human   865 LTFISYIGCGISAIFSAATLLTYVAFEKLRRDYPSKILMNLSTALLFLNLLFLLDGWITSFNV-D 928

  Fly   393 AACHTLAITMQFFFLAAFFWLNTMCFNIW----WTFRDFRPSSLERNQEALRRYL--YSLYAWGG 451
            ..|..:|:.:.||.||.|.|:.....:::    ..|..:           :|||:  :.:..||.
Human   929 GLCIAVAVLLHFFLLATFTWMGLEAIHMYIALVKVFNTY-----------IRRYILKFCIIGWGL 982

  Fly   452 PLLITFVAACVDQLPETTLLRPGFGQ----LYCWFDNRNLSIFAYFY----GPIGLLLCANIALF 508
            |.|:..|........| ...:..:|:    .:||..:.     ..||    |..|::...|||:|
Human   983 PALVVSVVLASRNNNE-VYGKESYGKEKGDEFCWIQDP-----VIFYVTCAGYFGVMFFLNIAMF 1041

  Fly   509 VSTTHQLTCGL-WKRDDVKSSSEKSALGRVCLKLVVVMGVTWIADILSWLVGGPHGV--WFFTDL 570
            :....|: ||. .||.:.....|.....|..:.|..::|:||.....:|   ||..:  .:...:
Human  1042 IVVMVQI-CGRNGKRSNRTLREEVLRNLRSVVSLTFLLGMTWGFAFFAW---GPLNIPFMYLFSI 1102

  Fly   571 INALQGVFIFIV-----VGCQPQVWTACRRIFCPRLR----HDITNT-TNGVQHSSSSQGLPSMA 625
            .|:|||:||||.     ...|.| |.  :.:.|.|.|    .|.:.| ||.::.||.:.| .|::
Human  1103 FNSLQGLFIFIFHCAMKENVQKQ-WR--QHLCCGRFRLADNSDWSKTATNIIKKSSDNLG-KSLS 1163

  Fly   626 GGTEITQNTTTTTTTTNTTATHMPSNPAEDEVP-------------EKAPIAPVAPIV-KMETIC 676
            ..:..:.:|..|:.:.:::.|:...|...|...             ::..|.||..:: |::..|
Human  1164 SSSIGSNSTYLTSKSKSSSTTYFKRNSHTDSASMDKSLSKLAHADGDQTSIIPVHQVIDKVKGYC 1228

  Fly   677  676
            Human  1229  1228

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mthl1	NP_001285340.1	7tm_4	329..579	CDD:304433	62/270 (23%)
ADGRG6	XP_006715579.1	CUB	44..147	CDD:238001
		LamG	154..338	CDD:304605
		GPS	802..847	CDD:280071	10/44 (23%)
		7tm_4	864..1111	CDD:304433	62/268 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4193
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810