Protein Alignment mthl1 and adgrd2

DIOPT Version :9

• Sequence 1: NP_001285340.1
• Gene: mthl1 / 32637
• FlyBaseID: FBgn0030766
• Length: 676
• Species: Drosophila melanogaster
• Sequence 2: XP_021334184.1
• Gene: adgrd2 / 571770
• ZFINID: ZDB-GENE-081104-190
• Length: 1145
• Species: Danio rerio
• Alignment Length: 530
• Identity: 115/530 - (21%)
• Similarity: 184/530 - (34%)
• Gaps: 163/530 - (30%)

  Fly   159 VAVVCLNDSQPINALEDPDYAANPLVQQEPPKASLRLSKCCGKWGSYNTQLQNCDLQPNHQAAVD 223
            ::...|.|.||::.      |.:..:|......|::....|..|        :.||..      |
Zfish   703 ISSTVLADEQPVSV------AIHFTLQHRLQNTSVKFIPVCAFW--------DFDLMS------D 747

  Fly   224 GLLRLSPQLPEGSYQTSYGLPDCGQPGGYSIAGDWQDAKLDRNTAMLQLPHKNLSAGQYCLEHTQ 288
            |                         ||:|..|            .:.:..:|.|...||...|.
Zfish   748 G-------------------------GGWSTKG------------CVVISTQNNSTSCYCNHTTN 775

  Fly   289 REGEVKIIACQHLFSSAAGAGIHDGSIGGTIEQANGQNLQKAVLTGGILVSIVFLSATLVAGFLL 353
            ....::|...|.       ..:||.            .||...|.|    |.|.|.| |:..|:|
Zfish   776 FALLLQIYEVQR-------DAVHDA------------GLQILSLIG----SAVSLCA-LIFTFIL 816

  Fly   354 -----------PAVHHALHWRCQICYVTCLLFGKILLAIEELSSSLQPGSAACHTLAITMQFFFL 407
                       ..||..|        :..|:..:.||.:.:.::..|   .||..:...:..|||
Zfish   817 FVAVGVPKSDRTTVHKNL--------MAALIVAQFLLILSDWAAGSQ---EACWLVTALLHLFFL 870

  Fly   408 AAFFWLNTMCFNIWWTFRDFRPSSLERNQEALRRYLYSLYAWGGPLLITFV--AACVDQLPETTL 470
            ::|.|:......:|........|      |..|..:|.:..||.|::|..|  .|.:||..
Zfish   871 SSFCWMLVEGLLLWSKVVSVNIS------EDRRMKMYYVLGWGLPVVIVAVTLVATLDQYK---- 925

  Fly   471 LRPGFGQLYCWFDNRNLSIFAYFYGPIGLLLCAN-IALF------VSTTHQLTCGLWKRDDVK-- 526
                 .|.:||.:.::..|:| |.||:..:|..| :.||      ||:..:....|....|.|
Zfish   926 -----AQQHCWLNLQSSVIWA-FAGPVLFVLAVNAVVLFRVVLVTVSSARRRAKMLTPSSDSKLH 984

  Fly   527 SSSEKSALGRVCLKLVVVMGVTW-------IADILSWLVGGPHGVWFFTDLINALQGVFIFIVVG 584
            :.....|..|..|.|:.|:|:||       ::|::::|        |.|  :||.||::||:|..
Zfish   985 TLDLTWAATRPVLILLPVLGLTWLCGVLVHLSDVMAYL--------FIT--LNAFQGLYIFLVYA 1039

  Fly   585 C-QPQVWTACRRIFCPRLRHDITNTTNGVQHSSSSQGLPSMAGGTEITQNTTTTTTTTNTTATHM 648
            . ..:|..|.|||...|.....||.:..:..      |||         ..:...:..::..||.
Zfish  1040 VYNSEVRNAIRRIQEKRKALSFTNCSQPISF------LPS---------QKSPRASWVHSLQTHS 1089

  Fly   649 PSNPAEDEVP 658
            ..:.:|...|
Zfish  1090 SRDSSESSTP 1099

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mthl1	NP_001285340.1	7tm_4	329..579	CDD:304433	69/278 (25%)
adgrd2	XP_021334184.1	LamG	204..402	CDD:328935
		GPS	735..779	CDD:307782	15/94 (16%)
		7tmB2_GPR144	792..1054	CDD:320383	80/315 (25%)
		TM helix 1	794..819	CDD:320383	11/29 (38%)
		TM helix 2	828..850	CDD:320383	6/29 (21%)
		TM helix 3	859..886	CDD:320383	6/26 (23%)
		TM helix 4	898..918	CDD:320383	6/19 (32%)
		TM helix 5	935..964	CDD:320383	9/29 (31%)
		TM helix 6	988..1015	CDD:320383	8/26 (31%)
		TM helix 7	1017..1042	CDD:320383	11/34 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X7362
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910