Protein Alignment mthl1 and adgrl3.1

DIOPT Version :10

• Sequence 1: NP_573140.1
• Gene: mthl1 / 32637
• FlyBaseID: FBgn0030766
• Length: 676
• Species: Drosophila melanogaster
• Sequence 2: XP_005170997.2
• Gene: adgrl3.1 / 560631
• ZFINID: ZDB-GENE-030131-7856
• Length: 1540
• Species: Danio rerio
• Alignment Length: 396
• Identity: 94/396 - (23%)
• Similarity: 154/396 - (38%)
• Gaps: 81/396 - (20%)

  Fly   297 ACQHLFSSAAGAGIHDGSIGGTIEQANGQNLQKAVLT----GGILVSIVFLSATLVAGFL----- 352
            :|.||.:.|.        :...:|......:.:.:|.    .|||:|:|.|   |:..|.
Zfish   843 SCTHLTNFAV--------LMAHVEVKKADQVHELLLDVITWVGILLSLVCL---LICIFTFCFFR 896

  Fly   353 -LPAVHHALHWR-CQICYVTCLLFGKILLAIEELSSSLQPGSAACHTLAITMQFFFLAAFFWLNT 415
             |.:..:.:|.. |...::...||      :..::.:.||  ..|...|..:.|||||||.|:..
Zfish   897 GLQSDRNTIHKNLCISLFIAETLF------LTGINRADQP--IVCAVFAALLHFFFLAAFTWMFL 953

  Fly   416 MCFNIWWTFRDFRPSSLERNQEALRRYLYSLYAWGGPLLITFVAACVDQLPETTLLRPGFGQLYC 480
            ....::....:...|...|.     :|.| |..:|.|.:|..|:|.||.....|       :..|
Zfish   954 EGVQLYIMLVEVFESEYSRT-----KYFY-LTGYGVPAVIVAVSAAVDYRSYGT-------ERVC 1005

  Fly   481 WFDNRNLSIFAYFYGPIGLLLCAN-----IALFVSTTHQLTCGLWKRDDVKSSSEKS-ALGRVCL 539
            |.......|:: |.||..|::..|     |||:....|   ..:.|.|.....:.|| .:|.:.
Zfish  1006 WLRLDTYFIWS-FIGPATLIIMLNVIFLGIALYKMFHH---TAILKPDSGCLDNIKSWVIGAIA- 1065

  Fly   540 KLVVVMGVTWIADILSWLVGGPHGVWFFTDLINALQGVFIFIVVGC--QPQV---WTACRRIFC- 598
             |:.::|:||...::..........:.|| :.|:|||:|||| ..|  |.:|   :..|.|..|
Zfish  1066 -LLCLLGLTWAFGLMYINESTVIMAYLFT-IFNSLQGMFIFI-FHCILQKKVRKEYGRCLRTHCC 1127

  Fly   599 --PRLRHDITNTTN-------GVQHSSSSQGLPSMAGGTEITQN---------TTTTTTTTNTTA 645
              ..:...|:.:|.       |...::|...:..|...|...|:         .::.|....|.|
Zfish  1128 SGKSVESTISTSTKTSTARTPGRYSTNSQSRIRRMWNDTVRKQSESSFITADMNSSATLNRGTMA 1192

  Fly   646 THMPSN 651
            .|:.||
Zfish  1193 NHLISN 1198

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mthl1	NP_573140.1	7tmB3_Methuselah-like	326..598	CDD:410632	75/293 (26%)
		TM helix 1	327..352	CDD:410632	8/28 (29%)
		TM helix 2	362..384	CDD:410632	3/22 (14%)
		TM helix 3	396..423	CDD:410632	9/26 (35%)
		TM helix 4	441..461	CDD:410632	7/19 (37%)
		TM helix 5	485..515	CDD:410632	10/34 (29%)
		TM helix 6	530..557	CDD:410632	7/27 (26%)
		TM helix 7	562..587	CDD:410632	11/26 (42%)
adgrl3.1	XP_005170997.2	None