DRSC/TRiP Functional Genomics Resources

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Protein Alignment mthl1 and Adgrg3

DIOPT Version :9

Sequence 1:NP_001285340.1 Gene:mthl1 / 32637 FlyBaseID:FBgn0030766 Length:676 Species:Drosophila melanogaster
Sequence 2:NP_766624.3 Gene:Adgrg3 / 54672 MGIID:1859670 Length:542 Species:Mus musculus


Alignment Length:327 Identity:81/327 - (24%)
Similarity:129/327 - (39%) Gaps:95/327 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly   295 IIACQHLFSSAAGAGIHDGSIGGTIEQANGQNLQKAVLTGGILVSIVFLSATLVA----GFLL-- 353
            :..|.||...|.       .:...::.|..|.|.: :...|..||::||:.|:|.    .|.|  
Mouse   238 VCRCDHLTFFAL-------LLRPILDLATAQTLTR-ISQAGSAVSMIFLAFTMVLYVAFRFSLQR 294

  Fly   354 ------PAVHHALHWRCQICYVTCLLFGKILLAIEELSSSLQPGSAACHTLAITMQFFFLAAFFW 412
                  |.:|.||.....:..:|.|:         .:.||.|...|:|...|....:|.|..|.|
Mouse   295 FKSEDAPKIHMALSISLFLLNLTFLI---------NVGSSSQGPPASCWVRAAIFHYFLLCVFTW 350

  Fly   413 LNTMCFNIWWTFRDFRPSSLERNQEALRRY---------LYSLYAWGGPLLITF---------VA 459
            :....|:::..              |:|.:         ..||.|||.|:|:..         |.
Mouse   351 MGLEAFHLYLL--------------AIRVFNTYFGHYFLKLSLLAWGLPVLVVIGAGSSNSYGVY 401

  Fly   460 ACVDQLPETTLLRPGFGQLYCWFDNRNLSIFAYFYG------PIGLLLCANIALFVSTTHQLTCG 518
            ...||...|:|      :| ||| .:..:::|..:|      ..|.::.|.:|..:.|...:|.|
Mouse   402 TIRDQENRTSL------EL-CWF-QKEPALYATVHGYFLVTFLFGAVVLALVAWKIFTLPSVTAG 458

  Fly   519 -----LWKRDDVKSSSEKSALGRVCLKLVVVMGVTWIADILSWLVGGPHGVWFFTDLINALQGVF 578
                 .||       |..:.||     |..::|:||...:|:.|  |...::.|| |:|:|||:|
Mouse   459 KGQGPTWK-------SVLTVLG-----LSSLVGMTWGLAVLTPL--GLSTIYVFT-LLNSLQGLF 508

  Fly   579 IF 580
            ||
Mouse   509 IF 510

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
mthl1NP_001285340.1 7tm_4 329..579 CDD:304433 71/290 (24%)
Adgrg3NP_766624.3 GPS 211..250 CDD:280071 4/18 (22%)
7tm_4 262..509 CDD:304433 72/293 (25%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG4193
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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