Protein Alignment mthl1 and Adgrg5

DIOPT Version :9

• Sequence 1: NP_001285340.1
• Gene: mthl1 / 32637
• FlyBaseID: FBgn0030766
• Length: 676
• Species: Drosophila melanogaster
• Sequence 2: NP_001139444.1
• Gene: Adgrg5 / 382045
• MGIID: 2685955
• Length: 524
• Species: Mus musculus
• Alignment Length: 464
• Identity: 103/464 - (22%)
• Similarity: 162/464 - (34%)
• Gaps: 148/464 - (31%)

  Fly   266 NTAMLQLPH-----KNLSAGQYCLEHTQREGEVKIIA----CQHLFSSAAGAG-IHDGSIGGTIE 320
            |.:.::.||     ..|:.|. |:  |.|..|:::|.    ..|||.....:. :::..:|..::
Mouse    96 NVSQVRAPHAMQFPAELTKGA-CV--TSRPAELRLICIYFFTAHLFQDDRNSSLLNNYVLGAQLD 157

  Fly   321 QANGQNLQKAVLTG--------GILVSIVFL----------------------SATLV------- 348
            .....||||.|...        |..||.||.                      |||.|
Mouse   158 HRPVNNLQKPVNISFWHNRSLEGYTVSCVFWKEGASKSSWGAWSPEGCYTEQPSATQVLCHCNHL 222

  Fly   349 ---------AGFLLPA-----VHHALHWRCQICYV----TCLLFGK------------------- 376
                     :|..:||     :.:.....|.|..|    |.||:.:
Mouse   223 TYFAVLMQLSGDPVPAELQVPLEYISFVGCSISIVASLLTILLYAQSRKQSDSTTRIHMNLNGSV 287

  Fly   377 ILLAIEELSSS-----LQPGSAACHTLAITMQFFFLAAFFWLNTMCFNIWWTFRDFRPSSLERNQ 436
            :||.:..|.||     ..| ...|..||..:.:..|::..|:....||::        ..|.|..
Mouse   288 LLLNVTFLLSSQMTLPTMP-RPVCKVLAAVLHYALLSSLTWMAIEGFNLY--------LFLGRVY 343

  Fly   437 EA-LRRYLYSL--YAWGGPLLITFV---------AACVDQLPETTLLRPGFGQL-YCWFDNRNL- 487
            .| :||||..|  ..||.|.|:..:         ..||..|.::.....||..: .||..:..:
Mouse   344 NAYIRRYLLKLCMLGWGFPALLVLLLLMIKSSVYGPCVTSLSKSQENGTGFQNVSMCWIRSPMVH 408

  Fly   488 SIFAYFYGPIGLLLCANIALFVSTTHQLTCGLWKRDDVKS--SSEKSALGRVCLKLVVVMGVTWI 550
            ||....||  |.....|:.: ::....:.|.|..|:...|  :...:|:   .|.|.|::|.||.
Mouse   409 SILVMGYG--GFTSLFNLVV-LAWALWILCRLRAREKALSPWAYRDTAM---VLGLTVLLGTTWT 467

  Fly   551 ADILSWLVGGPHGVW-----FFTDLINALQGVFIFIVVGCQPQVWTACRRIFCPRLRHDITNTTN 610
            ....|:      ||:     |...:.|:|.|.|:|:        |      ||.:.|:.......
Mouse   468 LAFFSF------GVFLLPQLFLFTIFNSLYGFFLFL--------W------FCSQKRYSDAEAKA 512

  Fly   611 GVQHSSSSQ 619
            .::..||||
Mouse   513 EMEAVSSSQ 521

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mthl1	NP_001285340.1	7tm_4	329..579	CDD:304433	76/349 (22%)
Adgrg5	NP_001139444.1	GPS	184..228	CDD:366827	7/43 (16%)
		7tm_GPCRs	242..514	CDD:391938	68/306 (22%)
		TM helix 1	244..268	CDD:341315	6/23 (26%)
		TM helix 2	277..298	CDD:341315	3/20 (15%)
		TM helix 3	311..333	CDD:341315	4/21 (19%)
		TM helix 4	353..369	CDD:341315	5/15 (33%)
		TM helix 5	405..428	CDD:341315	6/25 (24%)
		TM helix 6	449..474	CDD:341315	8/33 (24%)
		TM helix 7	478..503	CDD:341315	9/38 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4193
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900