Protein Alignment mthl1 and mthl10

DIOPT Version :9

• Sequence 1: NP_001285340.1
• Gene: mthl1 / 32637
• FlyBaseID: FBgn0030766
• Length: 676
• Species: Drosophila melanogaster
• Sequence 2: NP_788446.2
• Gene: mthl10 / 38057
• FlyBaseID: FBgn0035132
• Length: 585
• Species: Drosophila melanogaster
• Alignment Length: 572
• Identity: 134/572 - (23%)
• Similarity: 235/572 - (41%)
• Gaps: 143/572 - (25%)

  Fly   133 LFPNGTLYVRERALMVQPSDYCVDWEVAVVCLNDSQPINALEDPDYAANPLVQQEPPKASLR--- 194
            |||||:                .|:...:|      |...:...||..:.|.::...:..:|
  Fly    69 LFPNGS----------------YDYYGTIV------PAELVGTYDYIHSSLTERIEVREHVRGCV 111

  Fly   195 ------LSKCCGKWGSYNTQLQNC--DLQPN--------------HQAAVDGLLRLSPQLPEGSY 237
                  |:.||.....:|:::..|  |...|              :::.:  |:.:..|....|:
  Fly   112 CKFKSCLNICCPWRQVFNSEVDGCIIDHSDNRTWPDPPMLNITFRNESTI--LVNMFTQFAIQSF 174

  Fly   238 QTSYGLPDCGQPGGYSI---AGDWQDAKLDRNTAMLQLPHKNL-SAGQYCLEHTQREGEVKIIAC 298
            :      .|  |..:|:   ..:|.|..|..|.:||::..|.| ...::|:..|.
  Fly   175 R------PC--PKMFSLQPETNNWDDYLLFENGSMLRVDDKLLIRKNEFCMVPTY---------- 221

  Fly   299 QHLFSSAAGAGIHDGSIGGTIEQAN-----GQNLQKAVLTGGILVSIVFLSATLVAGFLLPAVHH 358
                       :::..:..||..||     ..:..|.:.:..::.||.|:..|:....|:|.:.:
  Fly   222 -----------VNESDMFYTIHPANCDMQDDHSTVKIINSYAMMFSIPFMMLTIAVYLLIPELRN 275

  Fly   359 ALHWRCQICYVTCLLFGKILLAIEELSSSLQPGSAACHTLAITMQFFFLAAFFWLNTMCFNIWWT 423
            . |.:..:||:..|..|...|...:| ..:......|.....|..|||:.|:.||:.:.|::|..
  Fly   276 Q-HGKSLVCYLIGLSVGYSSLCYVQL-YQVDATGVTCKVFGYTAYFFFMGAYMWLSVISFDLWHN 338

  Fly   424 FRDFRPSSLERNQEALRRYLYSLYAWGGPLLITFVAACVDQLPETTL---LRPGFGQ-LYCWFDN 484
            ||..|  .:.|.||..|...||||:||..|:......|..||  |.|   |:||.|. :|||.|.
  Fly   339 FRGTR--GINRFQEKKRFLFYSLYSWGIALVFLAFTYCAQQL--TNLPANLKPGIGDGVYCWLDM 399

  Fly   485 RNLSIFAYFYGPIGLLLCANIALFVSTTHQLTCGLWKRDDVKSSSEKSALG-------------- 535
            .|.:...||||||..::.||..:|:.|..::. |:.:......:||.|...
  Fly   400 SNWAAMIYFYGPILAIVVANTIMFIMTAIKIH-GVQREMARIIASENSTKNLRTEKDKRFYRAWS 463

  Fly   536 ----RVCLKLVVVMGVTWIADILSWLVGGPHG---VWFFTDLINALQGVFIFIVVGCQPQVWTAC 593
                .:.|:|.::||:||:.:::|:.||...|   :::.:||.||:||..||::.
  Fly   464 NYRFGLFLRLFLIMGITWLTELISYFVGSDKGWSKLFYISDLANAMQGFLIFMLF---------- 518

  Fly   594 RRIFCPRLRHDITNTTNGVQHSSSSQGLPSMAGGTEITQNTTTTTTTTNTTA 645
              :...:::|.|||..:.|:..|:.:            |:..:|.||:::.|
  Fly   519 --VMKKKVKHLITNRCSSVRDGSNQR------------QSQYSTKTTSSSVA 556

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mthl1	NP_001285340.1	7tm_4	329..579	CDD:304433	82/274 (30%)
mthl10	NP_788446.2	Methuselah_N	56..236	CDD:284145	38/219 (17%)
		7tm_4	244..514	CDD:304433	82/276 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462214
Domainoid	1	1.000	49	1.000	Domainoid score	I4416
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S8041
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D111500at6656
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.800