Protein Alignment mthl1 and Dh44-R1

DIOPT Version :9

• Sequence 1: NP_001285340.1
• Gene: mthl1 / 32637
• FlyBaseID: FBgn0030766
• Length: 676
• Species: Drosophila melanogaster
• Sequence 2: NP_610960.1
• Gene: Dh44-R1 / 36601
• FlyBaseID: FBgn0033932
• Length: 504
• Species: Drosophila melanogaster
• Alignment Length: 452
• Identity: 97/452 - (21%)
• Similarity: 151/452 - (33%)
• Gaps: 112/452 - (24%)

  Fly   283 CLEHTQREGEVKIIACQHLFSSAAGAGIH-DGSIGGT-IEQANGQ-------------------- 325
            |...|.| |.:.::.|.....     ||| |.|...| ...|||.
  Fly    62 CWPRTAR-GTLAVLQCMDELQ-----GIHYDSSKNATRFCHANGTWEKYTNYDACAHLPAPESVP 120

  Fly   326 ------NLQKAVLTGGILVSIVFLSATLV--AGFL-LPAVHHALHWRCQICYVTCLLFGKILLAI 381
                  .|...:...|..:|:|.||..|:  |.|. |..:.:.:|......|:...||..:||::
  Fly   121 EFEVIVELPTIIYYIGYTLSLVSLSLALIVFAYFKELRCLRNTIHANLFFTYIMSALFWILLLSV 185

  Fly   382 EELSSSLQPGSAACHTLAITMQFFFLAAFFWLNTMCFNIWW----TFRDFRPSSLERNQEALRRY 442
            :   .|::.|..:|..|.....||.|..|||:......::.    ||          :.:.||..
  Fly   186 Q---ISIRSGVGSCIALITLFHFFTLTNFFWMLVEGLYLYMLVVKTF----------SGDNLRFN 237

  Fly   443 LYSLYAWGGPLLITFVAACVDQLPETTLLRPGFGQLYC-WFDNRNLSIFAYFYGPIGLLLCANIA 506
            :|:...||||.|.....|....| ..|...|...::.| |....::...  :.||:..:|..|:.
  Fly   238 IYASIGWGGPALFVVTWAVAKSL-TVTYSTPEKYEINCPWMQETHVDWI--YQGPVCAVLIINLT 299

  Fly   507 LFVSTTHQLTCGLWKRDDVKSSSEKSALGRVCLKLVVVMGVTWIADILSWLVGGPHGVWFFTDLI 571
            ..:.....|...|...:.|::...:.| .:..|.|:.:.|:|::.     ::.||........:.
  Fly   300 FLLRIMWVLITKLRSANTVETRQYRKA-AKALLVLIPLFGITYLV-----VLAGPSESGLMGHMF 358

  Fly   572 NALQGVFI----FIVVGCQPQVWTACRRIFC-------PRLRHDITN---------------TTN 610
            ..|:.|.:    |.|           ...:|       ..|||.|:.               ||.
  Fly   359 AVLRAVLLSTQGFSV-----------SLFYCFLNSEVRNALRHHISTWRDTRTIQLNQNRRYTTK 412

  Fly   611 GVQHSSSSQGLPSM--------AGGTEITQNTTTTTTTTNTTA---THMPSNPAEDEVPEKA 661
            .......|....||        .|..|...::.||||.....|   .|..||.|...:|..|
  Fly   413 SFSKGGGSPRAESMRPLTSYYGRGKRESCVSSATTTTLVGQHAPLSLHRGSNNALHTMPTLA 474

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mthl1	NP_001285340.1	7tm_4	329..579	CDD:304433	57/257 (22%)
Dh44-R1	NP_610960.1	HRM	52..112	CDD:397086	14/55 (25%)
		7tmB1_DH_R	126..394	CDD:320391	65/300 (22%)
		TM helix 1	129..153	CDD:320391	6/23 (26%)
		TM helix 2	162..183	CDD:320391	4/20 (20%)
		TM helix 3	197..219	CDD:320391	7/21 (33%)
		TM helix 4	238..254	CDD:320391	6/15 (40%)
		TM helix 5	279..302	CDD:320391	4/24 (17%)
		TM helix 6	327..349	CDD:320391	5/26 (19%)
		TM helix 7	356..381	CDD:320391	5/35 (14%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462194
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840