Protein Alignment mthl1 and mthl15

DIOPT Version :9

• Sequence 1: NP_001285340.1
• Gene: mthl1 / 32637
• FlyBaseID: FBgn0030766
• Length: 676
• Species: Drosophila melanogaster
• Sequence 2: NP_723538.3
• Gene: mthl15 / 318914
• FlyBaseID: FBgn0051720
• Length: 718
• Species: Drosophila melanogaster
• Alignment Length: 707
• Identity: 168/707 - (23%)
• Similarity: 277/707 - (39%)
• Gaps: 182/707 - (25%)

  Fly    26 ILLQTLVSMSLAIEEMSPPPAAPPRPSPPPTVKLNKCCHSG-EYLND-GTCIAGSEALWLPMVYL 88
            :|.:.|:.:|...|:..|..:..         .:||||..| .|::: .||..|....::....:
  Fly   117 LLNRRLIVLSCEFEKNVPSQSVG---------FVNKCCPQGFIYVSENNTCKPGESDFFVYTSII 172

  Fly    89 VQQQRFFEPHGASPRFLKFLPNTRPTCRKDQTTEIFRSRGANVMLFPNGTLYVRERALMVQPSDY 153
                       :||  :.|..||. .| .|....:..:..:..:.|.|.:|..::....:..|.:
  Fly   173 -----------SSP--IIFFDNTL-NC-SDHRALVEYTLSSGKVHFHNNSLIWKDGTNSLPSSKF 222

  Fly   154 CVDWEVAVVCLNDSQPINALEDPDYAANPLVQQEPPKASLR-------------LSKCCGKW--- 202
            |::      .::||      :|.|.....|.:|   |..:|             :.:||.:.
  Fly   223 CIE------AIHDS------DDADLDRGALPEQ---KFLVRACQEMKICQKIPCIRRCCAEGEMY 272

  Fly   203 --GSYNTQ------------LQNCDL-----QPNHQAAVDGL----LRLSP-QLPEGSYQTSYGL 243
              |:::|.            .||.::     :|:....|.||    .||.| ..|:.|:..:
  Fly   273 AKGNFSTYCKIDGTDFKFEGFQNLNINANFSKPSDFGIVHGLQCPKFRLDPDNFPDDSHTIN--- 334

  Fly   244 PDCGQPGGYSIAGDWQDAKLDRNTAMLQLPHKNLSAGQYCLEHTQREGEVKIIACQHLFSSAAGA 308
                 |...|:        :..||      .|..:..|||:|..:...::....|
  Fly   335 -----PSNGSL--------IIHNT------FKTYTNTQYCVERVRPNQKLYTFLC---------- 370

  Fly   309 GIHDGSIGGTIEQANGQNLQKAVLTGGILVSIVFLSATLVAGFLLPAVHHALHWRCQICYVTCLL 373
              .|..:      ..|..::..:...|:|:|..|.:.||:. ::..|....|..:..||.|:.|.
  Fly   371 --FDNKV------VTGDRIRFKMYPIGLLISCCFYALTLIV-YISIAKLRNLPGKILICLVSSLF 426

  Fly   374 FGKILLAIEELSSSLQPGS--AACHTLAITMQFFFLAAFFWLNTMCFNIWWTFRDFRPSSLERNQ 436
            ...:.:|:    ..|:|.|  ..|......:.|..:|||.|:|...|:||.||...:..|.|::.
  Fly   427 AAYLGIAL----GQLRPTSNDDICFLSGFFVYFCLMAAFSWMNITSFDIWKTFGSTKLKSCEKSD 487

  Fly   437 EALRRYL--YSLYAWGGPLLITFVAACV---DQLPETTLLRPGFGQLYCWF--DNRNLSIFAYFY 494
              |||..  ||.|.||.|.|:|.:....   |.||:.  :||.||...|||  |:...:...:|.
  Fly   488 --LRRQFIWYSCYGWGLPTLLTGITIAFTKSDILPDA--VRPNFGHGRCWFTYDSFGSASLLFFS 548

  Fly   495 GPIGLLLCANIALFVSTTHQLTCGLWKRDDVKS---SSEKSALGR----------VCLKLVVVMG 546
            ||:|:|...|:.|||.|...  |...|.:..|.   :|:|..|.|          :..||..|||
  Fly   549 GPVGILFIINLVLFVLTMKY--CNKVKNEIYKMQSLNSDKPVLKRRFFQDKTRFVMNTKLCFVMG 611

  Fly   547 VTWIADILSWLVGGPHGVWFFT--DLINALQGVFIFIVVGCQPQVWTACRRIFCPRLRHDITNTT 609
            :||:.:|:|.|.......:|:|  |..|.|.|:|:||:.            :|..|:.::|. ..
  Fly   612 ITWLLEIVSILFYDHKKTFFWTISDSFNVLLGIFVFIIF------------VFKRRIYNEIM-FK 663

  Fly   610 NGVQHSSSSQGLPSMAGGTEITQNTTTTTTTTNTTATHMP---------SNPAEDEV 657
            .|:|.:.|:....:.||.|:    :...|:|..||..|.|         |...|:||
  Fly   664 FGLQSNPSTASTRTRAGVTK----SYAPTSTAMTTLRHSPGSCEFKRQTSTRPENEV 716

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mthl1	NP_001285340.1	7tm_4	329..579	CDD:304433	85/273 (31%)
mthl15	NP_723538.3	Mth_Ecto	<247..355	CDD:299804	22/129 (17%)
		7tm_4	385..646	CDD:304433	85/271 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	49	1.000	Domainoid score	I4416
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D111500at6656
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.920