Protein Alignment mthl1 and Adgrg5

DIOPT Version :9

• Sequence 1: NP_001285340.1
• Gene: mthl1 / 32637
• FlyBaseID: FBgn0030766
• Length: 676
• Species: Drosophila melanogaster
• Sequence 2: XP_008770523.1
• Gene: Adgrg5 / 307645
• RGDID: 1305559
• Length: 564
• Species: Rattus norvegicus
• Alignment Length: 365
• Identity: 66/365 - (18%)
• Similarity: 113/365 - (30%)
• Gaps: 146/365 - (40%)

  Fly   258 WQDAKLDRNTAML-------QLPHK---------NLS--------------------AGQY---- 282
            :||   |||:::|       ||.|:         |:|                    ||::
  Rat   138 FQD---DRNSSLLNNYVLGAQLDHRPVNNLQRPVNISFWHNRSLEGYTVTCVFWKEGAGKHSWGA 199

  Fly   283 -----CLEHTQREGEVKIIA-CQHLFSSAAGAGIHDGSIGGTIEQANGQNLQKAVLTGGILVSIV 341
                 |  :|::....:::. |.||...|            .:.|.:|..:...:.|....:|:|
  Rat   200 WSPKGC--YTEQPSPTQVLCHCNHLTYFA------------VLMQLSGDPVPTELQTPLEYISLV 250

  Fly   342 FLSATLVAGFLLPAVH-HALHWRCQICYVTCLLFGKILL--AIEELSSSLQPGS---AACHTLAI 400
            ..|.::||..|...:: |:.........:...|.|.:||  ....|||.:.|.:   :.|..||.
  Rat   251 GCSISIVASLLTILLNAHSRKLSDSTTRIHLNLNGSVLLLNITFLLSSQMVPPTVPRSVCTVLAA 315

  Fly   401 TMQFFFLAAFFWLNTMCFNIW------------------------------WTFRDF---RPSSL 432
            |:.:..|::..|:....||::                              ||..|.   :|...
  Rat   316 TLHYALLSSLTWMGVEGFNLYLLLGRVYNVYIRRVSSPLGAASSDDQELSVWTMCDLFLQKPGKW 380

  Fly   433 ERNQEALRRYLYSLYAWGGPLLITFVAACVDQLPETT--LLRPGFGQLYCWFDNRNLSIFAYFYG 495
            .|..|                       ||..|...:  ...||:|   .|:.:.:|.......|
  Rat   381 YRLPE-----------------------CVHVLGTQSHGTQHPGYG---LWWPHISLQPGGAGLG 419

  Fly   496 PIGLLL----------------CANIALFVSTTHQLTCGL 519
            .:..:.                |..:....:|.|.|..||
  Rat   420 SVDFVQATETGEGTESLGLSGHCHGVGSHCATGHHLVPGL 459

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mthl1	NP_001285340.1	7tm_4	329..579	CDD:304433	45/248 (18%)
Adgrg5	XP_008770523.1	GPS	184..228	CDD:396408	8/57 (14%)
		7tm_GPCRs	243..>349	CDD:421689	23/105 (22%)
		TM helix 1	243..268	CDD:410628	6/24 (25%)
		TM helix 2	277..299	CDD:410628	6/21 (29%)
		TM helix 3	311..338	CDD:410628	7/26 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4193
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900