Protein Alignment mthl1 and Adgrg3

DIOPT Version :9

• Sequence 1: NP_001285340.1
• Gene: mthl1 / 32637
• FlyBaseID: FBgn0030766
• Length: 676
• Species: Drosophila melanogaster
• Sequence 2: XP_038954076.1
• Gene: Adgrg3 / 291854
• RGDID: 1305674
• Length: 574
• Species: Rattus norvegicus
• Alignment Length: 324
• Identity: 82/324 - (25%)
• Similarity: 128/324 - (39%)
• Gaps: 89/324 - (27%)

  Fly   295 IIACQHLFSSAAGAGIHDGSIGGTIEQANGQNLQKAVLTGGILVSIVFLSATLVA----GFLL-- 353
            :..|.||...|.       .:..|::||..:.|.: :...|..||::||:.|:|.    .|.|
  Rat   270 VCRCDHLTFFAL-------LLRPTLDQATARTLTR-ISQAGSAVSMIFLAFTMVLYVAFRFSLQR 326

  Fly   354 ------PAVHHALHWRCQICYVTCLLFGKILLAIEELSSSLQPGSAACHTLAITMQFFFLAAFFW 412
                  |.:|.||.....:..:|.|:         .:.|..|...|:|...|....:|.|..|.|
  Rat   327 FKSEDAPKIHMALSTSLFLLNLTFLI---------NVGSGSQGPPASCWVRAAIFHYFLLCVFTW 382

  Fly   413 LNTMCFNIWW----TFRDFRPSSLERNQEALRRYL--YSLYAWGGPLLITF---------VAACV 462
            :....|:::.    .|..:           ...|.  .||..||.|:||..         |....
  Rat   383 MGLEAFHLYLLVIKVFNTY-----------FGHYFLKLSLLGWGLPVLIVIGVGSSNSYGVYTIR 436

  Fly   463 DQLPETTLLRPGFGQLYCWFDNRNLSIFAYFYG------PIGLLLCANIALFVSTTHQLTCG--- 518
            ||...|:|      :| ||| .:..:::|..:|      ..|.::.|.:|..:.|...:|.|
  Rat   437 DQENRTSL------EL-CWF-QKEPALYATVHGYFLVTFLFGAVVLAMVAWKIFTLPSVTAGKGQ 493

  Fly   519 --LWKRDDVKSSSEKSALGRVCLKLVVVMGVTWIADILSWLVGGPHGVWFFTDLINALQGVFIF 580
              .||       |..:.||     |..::|:||...:|:.|  |...|:.|| |:|:|||:|||
  Rat   494 GQTWK-------SVLTVLG-----LSSLVGMTWGLAVLTPL--GLSTVYIFT-LLNSLQGLFIF 542

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mthl1	NP_001285340.1	7tm_4	329..579	CDD:304433	71/287 (25%)
Adgrg3	XP_038954076.1	GPS	244..282	CDD:396408	4/18 (22%)
		7tm_GPCRs	292..551	CDD:421689	75/295 (25%)
		TM helix 1	294..319	CDD:410628	8/25 (32%)
		TM helix 2	333..355	CDD:410628	6/30 (20%)
		TM helix 3	366..393	CDD:410628	6/26 (23%)
		TM helix 4	406..426	CDD:410628	7/19 (37%)
		TM helix 5	454..481	CDD:410628	5/26 (19%)
		TM helix 6	495..522	CDD:410628	10/38 (26%)
		TM helix 7	524..549	CDD:410628	11/20 (55%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4193
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810