Protein Alignment mthl1 and ADGRF2

DIOPT Version :9

• Sequence 1: NP_001285340.1
• Gene: mthl1 / 32637
• FlyBaseID: FBgn0030766
• Length: 676
• Species: Drosophila melanogaster
• Sequence 2: NP_001355044.1
• Gene: ADGRF2 / 222611
• HGNCID: 18991
• Length: 708
• Species: Homo sapiens
• Alignment Length: 434
• Identity: 82/434 - (18%)
• Similarity: 139/434 - (32%)
• Gaps: 164/434 - (37%)

  Fly   183 LVQQEPPKASLRLSKCCGKWGSYNTQ--LQNCD-LQPNHQAAV----------DGLLRLSPQLPE 234
            |:.::..|:..|.::|.| |.|...:  .|.|. :|.|.|.||          ...:.:||.:.|
Human   379 LIFEKISKSEERRTQCVG-WHSVENRWDQQACKMIQENSQQAVCKCRPSKLFTSFSILMSPHILE 442

  Fly   235 G---SYQTSYGLPDCGQPGGYSIAGDWQDAKLDRNTAMLQLPHKNLSAGQYCLEHTQREGEVKII 296
            .   :|.|..||       |.||.                                      .:|
Human   443 SLILTYITYVGL-------GISIC--------------------------------------SLI 462

  Fly   297 ACQHLFSSAAGAGIHDGSIGGTIEQANGQNLQKAVLTGGILVSIVFLSATL--------VAGFLL 353
            .|.                  :||......:.|..:|....|.||.::|||        ||.||.
Human   463 LCL------------------SIEVLVWSQVTKTEITYLRHVCIVNIAATLLMADVWFIVASFLS 509

  Fly   354 -PAVHHALHWRCQICYVTCLLFGKILLAIEELSSSLQPGSAACHTLAITMQFFFLAAFFWLNT-- 415
             |..||                                  ..|......:.||:|:.|||:..
Human   510 GPITHH----------------------------------KGCVAATFFVHFFYLSVFFWMLAKA 540

  Fly   416 --MCFNIWWTFRDFRPSSLERNQEALRRYLYSLYAWGGPLLITFVAACVDQLPETTLLRPGFGQL 478
              :.:.|...|.....|.|..:       |:|: .:|.||.|..:.....:        ||.|.|
Human   541 LLILYGIMIVFHTLPKSVLVAS-------LFSV-GYGCPLAIAAITVAATE--------PGKGYL 589

  Fly   479 ---YCWFD-NRNLSIFAYFYGPIGLLL--CANIALFVSTTHQLTCGLWKRDDVKSSSEKSALGRV 537
               .||.: :...::.|:....:.:::  ...:.|.:..|.:...|.....:|:      |:.|:
Human   590 RPEICWLNWDMTKALLAFVIPALAIVVVNLITVTLVIVKTQRAAIGNSMFQEVR------AIVRI 648

  Fly   538 CLKLVV---VMGVTW---IADILSWLVGGPHGVWFFTDLINALQ 575
            ...:.:   ::|:||   :|.::.......|.::   .|:||.|
Human   649 SKNIAILTPLLGLTWGFGVATVIDDRSLAFHIIF---SLLNAFQ 689

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mthl1	NP_001285340.1	7tm_4	329..579	CDD:304433	54/272 (20%)
ADGRF2	NP_001355044.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4193
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900