Protein Alignment mthl1 and ADGRG3

DIOPT Version :9

• Sequence 1: NP_001285340.1
• Gene: mthl1 / 32637
• FlyBaseID: FBgn0030766
• Length: 676
• Species: Drosophila melanogaster
• Sequence 2: XP_005255899.1
• Gene: ADGRG3 / 222487
• HGNCID: 13728
• Length: 596
• Species: Homo sapiens
• Alignment Length: 442
• Identity: 88/442 - (19%)
• Similarity: 145/442 - (32%)
• Gaps: 149/442 - (33%)

  Fly   256 GDWQDAKLDRNTAMLQLPHKNLSAGQYCLEHTQREGEVKIIACQHLFSSAAGAGIHDGSIGGTIE 320
            |||                    :.:.|....:.||.|  ..|.||...|.       .:..|::
Human   226 GDW--------------------SSEGCSTEVRPEGTV--CCCDHLTFFAL-------LLRPTLD 261

  Fly   321 QANGQNLQKAVLTGGILVSIVFLSATLVA-GFLLPAVHHALH----------------------- 361
            |:....|.: :...|..||::||:.|::. .||.|.:.|..|
Human   262 QSTVHILTR-ISQAGCGVSMIFLAFTIILYAFLSPGLGHGPHPQQAECDLPAGRIAGPCERGLER 325

  Fly   362 ------------WRCQIC----------YVTCLLFGKILLA----IEELSSSLQPGSAACHTLAI 400
                        |..::.          .:...|.|.:.|.    :..:.|..:...|||.....
Human   326 QEKLPPAPQGGAWHLRLSRERFKSEDAPKIHVALGGSLFLLNLAFLVNVGSGSKGSDAACWARGA 390

  Fly   401 TMQFFFLAAFFWLNTMCFNIWWTFRDFRPSSLERNQEALRRY---------LYSLYAWGGPLLIT 456
            ...:|.|.||.|:....|:::..              |:|.:         ..||..||.|.|:.
Human   391 VFHYFLLCAFTWMGLEAFHLYLL--------------AVRVFNTYFGHYFLKLSLVGWGLPALMV 441

  Fly   457 FVAACV---------DQLPETTLLRPGFGQLYCWFDNRN------LSIFAYFYGP--IGLLLCAN 504
            ......         |:...|:|      :| |||....      :::..||...  .|:::.|.
Human   442 IGTGSANSYGLYTIRDRENRTSL------EL-CWFREGTTMYALYITVHGYFLITFLFGMVVLAL 499

  Fly   505 IALFVSTTHQLTCGLWKRDDVKSSSEKSALGRVCLKLVVVMGVTWIADILSWLVGGPHGVWFFTD 569
            :...:.|..:.|.       ||...:........|.|..::||||...|.:.|  |...|:.|.
Human   500 VVWKIFTLSRATA-------VKERGKNRKKVLTLLGLSSLVGVTWGLAIFTPL--GLSTVYIFA- 554

  Fly   570 LINALQGVFIFIVVGCQPQVWTACRRIFCPRLRHDITNTTNGVQ--HSSSSQ 619
            |.|:||||||     |   .|...  ::.|.....::::|..:.  ||:|.:
Human   555 LFNSLQGVFI-----C---CWFTI--LYLPSQSTTVSSSTARLDQAHSASQE 596

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mthl1	NP_001285340.1	7tm_4	329..579	CDD:304433	65/325 (20%)
ADGRG3	XP_005255899.1	GPS	213..255	CDD:280071	11/57 (19%)
		7tm_4	355..564	CDD:304433	53/239 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4193
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810