DRSC/TRiP Functional Genomics Resources

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Protein Alignment mthl1 and adgre14

DIOPT Version :9

Sequence 1:NP_001285340.1 Gene:mthl1 / 32637 FlyBaseID:FBgn0030766 Length:676 Species:Drosophila melanogaster
Sequence 2:XP_021330419.1 Gene:adgre14 / 108182849 ZFINID:ZDB-GENE-131120-49 Length:505 Species:Danio rerio


Alignment Length:262 Identity:59/262 - (22%)
Similarity:113/262 - (43%) Gaps:42/262 - (16%)


- Green bases have known domain annotations that are detailed below.


  Fly   336 ILVSIVFLSATLVAGFL----LPAVHHALHWRCQICYVTCLLFGKILLAIEELSSSLQPGSAACH 396
            ::|.::|.|..|:. |.    .|.|::..  |..|| ::.||...:.|..::..|.::.....|.
Zfish   225 VIVGLLFFSLALLT-FTRCQWSPGVNNVA--RINIC-ISLLLAHLLFLLTQQFLSLIRRQKVLCM 285

  Fly   397 TLAITMQFFFLAAFFWLNTMCFNIWWTFRDFRPSSLERNQEALRRYLYSLYAWGGPLLITFVAAC 461
            .::..:.|.||:.|.|:......::...::....| .:.:..||..|..:..:...|::..::|.
Zfish   286 LISGLLHFLFLSGFVWMFIEAVLLFICVKNLSQIS-SQMKNVLRNKLLCVIGYAVALVVVSISAA 349

  Fly   462 VDQLPETTLLRPGFGQLYCWFDNRNLSIFAYFYGPIGLLLCANIALFVSTTHQLTCGLWKRD-DV 525
            |  :|.      |:|...||.......|:: |.||:.:::..|:.||:|....|.....|.: ||
Zfish   350 V--VPN------GYGSEKCWIQMHKGFIWS-FLGPVTIIIALNVILFISIGFSLKSAFKKLNADV 405

  Fly   526 KSSSEKSALGRVCLKLVVVMGVTWIADILSWLVGGPHGVWFFTD----------LINALQGVFIF 580
            ...::...:....|...||:|.:||             :.|||:          ::|:.||.|||
Zfish   406 SQLNQTKIVMFKTLAQFVVLGCSWI-------------LGFFTNSSKVLEILFLILNSQQGTFIF 457

  Fly   581 IV 582
            ::
Zfish   458 LI 459

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
mthl1NP_001285340.1 7tm_4 329..579 CDD:304433 56/257 (22%)
adgre14XP_021330419.1 GPS 167..205 CDD:197639
7tm_GPCRs 214..476 CDD:333717 59/262 (23%)
TM helix 1 217..241 CDD:320095 5/16 (31%)
TM helix 2 250..271 CDD:320095 6/23 (26%)
TM helix 3 285..307 CDD:320095 5/21 (24%)
TM helix 4 331..347 CDD:320095 2/15 (13%)
TM helix 5 365..388 CDD:320095 6/23 (26%)
TM helix 6 412..435 CDD:320095 7/35 (20%)
TM helix 7 439..464 CDD:320095 6/21 (29%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG4193
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1153592at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
32.820

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