DRSC/TRiP Functional Genomics Resources

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Protein Alignment mthl1 and adgre9

DIOPT Version :9

Sequence 1:NP_001285340.1 Gene:mthl1 / 32637 FlyBaseID:FBgn0030766 Length:676 Species:Drosophila melanogaster
Sequence 2:XP_021333151.1 Gene:adgre9 / 101883848 ZFINID:ZDB-GENE-121214-61 Length:660 Species:Danio rerio


Alignment Length:260 Identity:65/260 - (25%)
Similarity:107/260 - (41%) Gaps:38/260 - (14%)


- Green bases have known domain annotations that are detailed below.


  Fly   336 ILVSIVFLSATLVAGFLL----PAVHHALHWRCQICYVTCLLFGKILLAIEELSSSLQPGSAACH 396
            ::|.:||.|..|:: |.|    |.|::..  |..|| ::.|....:.|..::..|.::|....|.
Zfish   397 VIVGLVFFSLALLS-FALCQWSPGVNNVA--RINIC-ISLLSAHLLFLLTQQFLSLIRPQQVFCV 457

  Fly   397 TLAITMQFFFLAAFFW------LNTMCFNIWWTFRDFRPSSLERNQEALRRYLYS--LYAWGGPL 453
            .:|..:.|.||:||.|      |..:|.           .:|.|.....:..|.|  |...|..|
Zfish   458 AIAGLLHFLFLSAFVWMFIEAVLLFICV-----------QNLSRISSKKKEVLSSGFLCVIGYVL 511

  Fly   454 LITFVAACVDQLPETTLLRPGFGQLYCWFDNRNLSIFAYFYGPIGLLLCANIALFVSTTHQLTCG 518
            .:..|...:..:||      |:|...||.......|:: |.||:.::|..|...|:.....|...
Zfish   512 ALVVVGVSIGLVPE------GYGSEQCWIKTAEGFIWS-FLGPVCVILALNTIFFIKIVLTLNST 569

  Fly   519 LWKRD-DVKSSSEKSALGRVCLKLVVVMGVTWIADILSWLVGGPHGVWFFTDLINALQGVFIFIV 582
            |...: :|....:...|....|...||:|..|   ||.:.:.|...:.....::|:.||.|||::
Zfish   570 LKNLNAEVSQMKQTKILAFKTLSQFVVLGCPW---ILGFFINGSEVLEILFLVLNSQQGTFIFVI 631

  Fly   583  582
            Zfish   632  631

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
mthl1NP_001285340.1 7tm_4 329..579 CDD:304433 62/255 (24%)
adgre9XP_021333151.1 GPS 335..380 CDD:197639
7tm_GPCRs 389..648 CDD:333717 65/260 (25%)
TM helix 1 389..413 CDD:320095 6/16 (38%)
TM helix 2 422..443 CDD:320095 5/23 (22%)
TM helix 3 457..479 CDD:320095 7/21 (33%)
TM helix 4 503..519 CDD:320095 4/15 (27%)
TM helix 5 537..560 CDD:320095 6/23 (26%)
TM helix 6 584..609 CDD:320095 8/27 (30%)
TM helix 7 611..636 CDD:320095 6/21 (29%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG4193
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
21.810

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