DRSC/TRiP Functional Genomics Resources

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Protein Alignment mthl1 and adgre13

DIOPT Version :9

Sequence 1:NP_001285340.1 Gene:mthl1 / 32637 FlyBaseID:FBgn0030766 Length:676 Species:Drosophila melanogaster
Sequence 2:XP_021327151.1 Gene:adgre13 / 100538238 ZFINID:ZDB-GENE-150505-3 Length:303 Species:Danio rerio


Alignment Length:306 Identity:71/306 - (23%)
Similarity:131/306 - (42%) Gaps:48/306 - (15%)


- Green bases have known domain annotations that are detailed below.


  Fly   336 ILVSIVFLS-ATLVAGFLL--PAVHHALHWRCQICYVTCLLFGKILLAIEELSSSLQPGSAACHT 397
            ::|.::|.| |.|...|..  |.|::..  |..|| ::.||...:.|..::..|.::.....|..
Zfish    23 VIVGLLFFSLALLTFAFCQWGPGVNNVA--RINIC-ISLLLAHLLFLLTQQFLSLIRRQQMLCEV 84

  Fly   398 LAITMQFFFLAAFFWLNTMCFNIWWTFRDF-RPSSLERNQEALRRYLYSLYAWGGPLLITFVAAC 461
            ::..:.|.||:.|.|:......::...::. :.||.:||  .||.....:..:...|::..::|.
Zfish    85 ISGLLHFLFLSGFVWMFIEAVLLFICVKNLSQISSQKRN--VLRNIFLCVIGYAVALVVVGISAA 147

  Fly   462 VDQLPETTLLRPGFGQLYCWFDNRNLSIFAYFYGPIGLLLCANIALFVSTTHQLTCGLWKRD-DV 525
            |  :|:      |:|...||.......|:: |.||:.::|..|:.||:.....|.....|.: ||
Zfish   148 V--VPK------GYGSEKCWIKMDKGFIWS-FLGPVTVILALNVILFIGIGVSLKSAFKKLNADV 203

  Fly   526 KSSSEKSALGRVCLKLVVVMGVTWIADILSWLVGGPHGVWFFTD----------LINALQGVFIF 580
            ...::...:....|...||:|.:||             :.|||:          ::|:.||.|||
Zfish   204 SQLNQTKIIMFKTLAQFVVLGCSWI-------------LGFFTNSSKVLEILFLILNSQQGTFIF 255

  Fly   581 IVV-----GCQPQVWTACRRIFCPRLRHDITNTTNGVQHSSSSQGL 621
            ::.     |.:.:.......::| .|:....|.|:.....|:.|||
Zfish   256 LIYCVLNKGIRQEYRKLFTSLYC-GLKPKNINWTSENTEDSTIQGL 300

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
mthl1NP_001285340.1 7tm_4 329..579 CDD:304433 59/257 (23%)
adgre13XP_021327151.1 7tm_GPCRs 12..274 CDD:333717 63/277 (23%)
TM helix 1 15..39 CDD:320095 5/15 (33%)
TM helix 2 48..69 CDD:320095 6/23 (26%)
TM helix 3 83..105 CDD:320095 5/21 (24%)
TM helix 4 129..145 CDD:320095 1/15 (7%)
TM helix 5 163..186 CDD:320095 7/23 (30%)
TM helix 6 210..233 CDD:320095 7/35 (20%)
TM helix 7 237..262 CDD:320095 6/24 (25%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1153592at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
11.010

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