Protein Alignment mthl1 and adgrg4b

DIOPT Version :10

• Sequence 1: NP_573140.1
• Gene: mthl1 / 32637
• FlyBaseID: FBgn0030766
• Length: 676
• Species: Drosophila melanogaster
• Sequence 2: XP_021335026.2
• Gene: adgrg4b / 100331278
• ZFINID: ZDB-GENE-091204-201
• Length: 1354
• Species: Danio rerio
• Alignment Length: 438
• Identity: 86/438 - (19%)
• Similarity: 152/438 - (34%)
• Gaps: 114/438 - (26%)

  Fly   250 GGYSIAGDW-QDAKLDRNTAMLQLPHKNLSAGQYCLEHTQREGEVKIIACQHLFSSAAGAGIHDG 313
            ||:|..|.| .:...|..|               ||             |.|:        .|.|
Zfish   936 GGWSPKGCWTYNISKDYTT---------------CL-------------CDHM--------THFG 964

  Fly   314 ---SIGGTIEQANGQNLQKAVLTGGILVSIVFLSATLVAGFLLPAVHHALHWRCQICYVTCLLFG 375
               .:..|......:.:...:...|..||..||..|::...||..:......:..:.....||..
Zfish   965 VLVDVSRTPIDEKNERILTIITYMGCGVSSCFLGITVLTYTLLEKLRRDYPSKILLNLSLALLGL 1029

  Fly   376 KILLAIEELSSSLQPGS-AACHTLAITMQFFFLAAFFWLNTMCFNIWW----TFRDFRPSSLERN 435
            .::..:....||.  |: ..|..:|.|:.:|.|.:|.|:.....|:::    .|..:.||.:.:
Zfish  1030 NLVFLLNSWISSF--GNYGLCIAVAATLHYFLLTSFTWMGLGAVNMYFALVKVFNVYVPSYILK- 1091

  Fly   436 QEALRRYLYSLYAWGGPLLITFVAACVDQLPETTLLRPGFG-----------QLYCWFDNR---N 486
                    :.|..||.||:|..:...:.        |..:|           :::||..|.   .
Zfish  1092 --------FCLLGWGIPLIICGLVLAIK--------RDAYGLSDSQSTLDDSEMFCWVKNDVVFY 1140

  Fly   487 LSIFAYFYGPIGLLLCANIALFVSTTHQLTCGLWKRDDVKSSSEKSALG---------RVCLKLV 542
            :|:.:|    |..:|..|.::|:....|          :::.......|         |....|.
Zfish  1141 VSVVSY----IAFILLCNGSIFLVVLIQ----------IRNMQVNQPAGTRSGILKDLRAVASLT 1191

  Fly   543 VVMGVTWIADILSWLVGGPHGVW--FFTDLINALQGVFIFIV-------VGCQPQVWTACRRIFC 598
            .::|:||....|:|   ||..|:  :...::|:|||.|||:.       |..|.::...|.....
Zfish  1192 FLLGLTWSVAFLAW---GPVKVFLLYLFSIMNSLQGFFIFVFHCLVKENVRKQWRIHLCCGAFKL 1253

  Fly   599 PRLRHDITNTTNGVQHSSSSQGLPS-MAGGTEITQNTTTTTTTTNTTA 645
            ..........|...:|..:.....| ||....|..|:|.::|.::.::
Zfish  1254 QEYSEWSQTATVVPKHKPNPPNTFSFMASVRSIKSNSTQSSTVSSESS 1301

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mthl1	NP_573140.1	7tmB3_Methuselah-like	326..598	CDD:410632	63/308 (20%)
		TM helix 1	327..352	CDD:410632	6/24 (25%)
		TM helix 2	362..384	CDD:410632	2/21 (10%)
		TM helix 3	396..423	CDD:410632	7/30 (23%)
		TM helix 4	441..461	CDD:410632	6/19 (32%)
		TM helix 5	485..515	CDD:410632	6/32 (19%)
		TM helix 6	530..557	CDD:410632	7/35 (20%)
		TM helix 7	562..587	CDD:410632	9/33 (27%)
adgrg4b	XP_021335026.2	None