Protein Alignment mbt and SSK2

DIOPT Version :10

• Sequence 1: NP_523375.2
• Gene: mbt / 32631
• FlyBaseID: FBgn0025743
• Length: 639
• Species: Drosophila melanogaster
• Sequence 2: NP_014428.1
• Gene: SSK2 / 855765
• SGDID: S000005314
• Length: 1579
• Species: Saccharomyces cerevisiae
• Alignment Length: 292
• Identity: 89/292 - (30%)
• Similarity: 150/292 - (51%)
• Gaps: 43/292 - (14%)

  Fly   372 NKIGEGSTGTVCIATDKSTGRQVAVKKMDLRKQQRRELLF----NEVVIMRDYHHPNIVETYSSF 432
            |.||.|:.|.|..|.|...|..:|||:::::..:..:.:|    .|:.::...:|||||..|...
Yeast  1270 NFIGGGTFGRVYSAVDLDNGEILAVKEINIQDSKSMQKIFPLIKEEMSVLEILNHPNIVSYYGVE 1334

  Fly   433 LVNDELWVVMEYLEGGALTDIVTHSRMDEEQIATV-CKQCLKALAYLHSQGVIHRDIKSDSILLA 496
            :..|::.:.|||.|||:|..::.|.|:::|.:..| ..|.|:.|||||..|::|||:|.::|||.
Yeast  1335 VHRDKVNIFMEYCEGGSLAALLEHGRIEDEMVTQVYTLQLLEGLAYLHESGIVHRDVKPENILLD 1399

  Fly   497 ADGRVKLSDFGFCAQVSQELPKRKS--------------------------------LVGTPYWM 529
            .:|.:|..|||...:::....:..|                                ::|||.:|
Yeast  1400 FNGVIKYVDFGAAKKIANNGTRLASMNKIENADGEHEDVTHVSDSKAVKNNENALLDMMGTPMYM 1464

  Fly   530 SPEVI----SRLPYGPEVDIWSLGIMVIEMVDGEPPFFN-EPPLQAMRRIRDMQPPNLKNAHKVS 589
            :||.|    ::...|.: |:||||.:|:||:.|..|:.| :.....|..:.....|......:||
Yeast  1465 APESITGSTTKGKLGAD-DVWSLGCVVLEMITGRRPWANLDNEWAIMYHVAAGHTPQFPTKDEVS 1528

  Fly   590 PRLQSFLDRMLVRDPAQRATAAELLAHPFLRQ 621
            .....||:|.|:::|::||:|.|||..|::.|
Yeast  1529 SAGMKFLERCLIQNPSKRASAVELLMDPWIVQ 1560

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mbt	NP_523375.2	CRIB_PAK_like	9..54	CDD:238526
		STKc_PAK_II	360..620	CDD:270815	88/289 (30%)
SSK2	NP_014428.1	STKc_MEKK4	1265..1558	CDD:270796	88/288 (31%)