Protein Alignment mbt and SKM1

DIOPT Version :9

• Sequence 1: NP_523375.2
• Gene: mbt / 32631
• FlyBaseID: FBgn0025743
• Length: 639
• Species: Drosophila melanogaster
• Sequence 2: NP_014528.1
• Gene: SKM1 / 854036
• SGDID: S000005473
• Length: 655
• Species: Saccharomyces cerevisiae
• Alignment Length: 676
• Identity: 178/676 - (26%)
• Similarity: 298/676 - (44%)
• Gaps: 197/676 - (29%)

  Fly     7 KKPL---ISMPSNFEHRVHTGFDKRENKYVGLPLQWASIVGNNQILKSS-NRPLPLVDPSEITPT 67
            |.||   :|.|:||.|:||.|||.:...:||:|..||.::..::|.... ||
Yeast   116 KCPLLSGVSSPTNFTHKVHVGFDPKVGNFVGVPDSWAKLLQTSEITYDDWNR------------- 167

  Fly    68 EILDLKTIVRP---HHNNNKADTTSLNSSSTMMMGSMAPMNPM-APGAHPMMSHGPGMMMPPETG 128
               :.|.:::.   :.:.|..||...|..    :.:...:.|: :|                 |.
Yeast   168 ---NSKAVIKALQFYEDYNGLDTMQFNDH----LNTSLDLKPLKSP-----------------TR 208

  Fly   129 GIVLPKTSHVARSNS--------------LRSSSPPRVR------RVANVPPSVPEEEGPPAAGT 173
            .|:..:|:.:.||.|              .:|...|..|      :..|:..:...|||
Yeast   209 YIINKRTNSIKRSVSRTLRKGKTDSILPVYQSELKPFPRPSDDDYKFTNIEDNKVREEG------ 267

  Fly   174 PGVGGASSGGFKPPGAHPSLLYNSQHAHANGATGPLAVRTD---QTNLQQYRSN-------LAPP 228
                               .::.|:.:.|:..|..|..:..   |::|:::.:|       |||.
Yeast   268 -------------------RVHVSKESTADSQTKQLGKKEQKVIQSHLRRHDNNSTFRPHRLAPS 313

  Fly   229 SGGSMPQQQQTSPVGSVASGTRSNHSHTNNGNSGGSYPPMYPTSHQQQQQQQQQAKQGGDQNQ-- 291
                             |..|:::.|.|                 :..::...:.|...|.|:
Yeast   314 -----------------APATKNHDSKT-----------------KWHKEDLLELKNNDDSNEII 344

  Fly   292 ---NPLHPHAHPHPHHHQHLAKSASRASSSSGGASSAAQQASGASGGAAGQPKQDQRLTHEQFRA 353
               ..:....:|.|:.                      |....|..||:|.....:|:...|
Yeast   345 MKMKTVAIDVNPRPYF----------------------QLVEKAGQGASGAVYLSKRIKLPQ--- 384

  Fly   354 ALQMVVSAGDPRENLDHFNKIGEGSTGTVCIATDKSTGRQVAVKKMDLRKQQRRELLFNEVVIMR 418
                   ..|||....|.:::               .|.:||:|::.|.:|.:::|:.||:::|.
Yeast   385 -------ENDPRFLKSHCHRV---------------VGERVAIKQIRLSEQPKKQLIMNELLVMN 427

  Fly   419 DYHHPNIVETYSSFLVND-ELWVVMEYLEGGALTDIV---------THSR-MDEEQIATVCKQCL 472
            |....|||....:::::| ||||:|||:|||.||||:         .||. ::|.|:|.:.|:..
Yeast   428 DSRQENIVNFLEAYIIDDEELWVIMEYMEGGCLTDILDAVARSNTGEHSSPLNENQMAYIVKETC 492

  Fly   473 KALAYLHSQGVIHRDIKSDSILLAADGRVKLSDFGFCAQVSQELPKRKSLVGTPYWMSPEVISRL 537
            :.|.:||::.:||||||||:|||.:.|.||::|||||.:::::..||.::|||||||:||::::.
Yeast   493 QGLKFLHNKKIIHRDIKSDNILLNSQGLVKITDFGFCVELTEKRSKRATMVGTPYWMAPEIVNQK 557

  Fly   538 PYGPEVDIWSLGIMVIEMVDGEPPFFNEPPLQAMRRIRDMQPPNLKNAHKVSPRLQSFLDRMLVR 602
            .|..:||:||||||:|||::||||:.||.||:|:..|.:...|.|::...||.:.:.|||..|..
Yeast   558 GYDEKVDVWSLGIMLIEMIEGEPPYLNEDPLKALYLIANNGSPKLRHPESVSKQTKQFLDACLQV 622

  Fly   603 DPAQRATAAELLAHPFLRQAGPPSLL 628
            :...||:..:||...||..|..|..|
Yeast   623 NVESRASVRKLLTFEFLSMACSPEQL 648

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mbt	NP_523375.2	CRIB_PAK_like	9..54	CDD:238526	18/48 (38%)
		STKc_PAK_II	360..620	CDD:270815	107/270 (40%)
		S_TKc	372..619	CDD:214567	102/257 (40%)
SKM1	NP_014528.1	PH_Cla4_Ste20	4..113	CDD:270097
		PBD	122..180	CDD:395634	19/73 (26%)
		STKc_PAK	359..640	CDD:270789	114/327 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0578
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR48015
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.910