DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mbt and MAPKKK18

DIOPT Version :9

Sequence 1:	NP_523375.2	Gene:	mbt / 32631	FlyBaseID:	FBgn0025743	Length:	639	Species:	Drosophila melanogaster
Sequence 2:	NP_172003.1	Gene:	MAPKKK18 / 839324	AraportID:	AT1G05100	Length:	339	Species:	Arabidopsis thaliana

Alignment Length:	280	Identity:	92/280 - (32%)
Similarity:	142/280 - (50%)	Gaps:	28/280 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   374 IGEGSTGTVCIATDKSTGRQVAVKKMDLRKQQRRELLFNEVVIMRDYHHPNIVE------TYSSF 432
            :|.|||.||..||...:|..:|||..:.   .|.|.|..|..|:...:.|.::.      |...|
plant     9 LGRGSTATVSAATCHESGETLAVKSAEF---HRSEFLQREAKILSSLNSPYVIGYRGCEITREPF 70

  Fly   433 LVNDELW---VVMEYLEGGALTDIVTHSR--MDEEQIATVCKQCLKALAYLH-SQGVIHRDIKSD 491
            ..|.|..   ::|||...|.|||:.|.:.  :||.::....:|.|..|.|:| |:|:.|.|||..
plant    71 HNNGEATTYSLLMEYAPYGTLTDVATKNGGFIDEARVVKYTRQILLGLEYIHNSKGIAHCDIKGS 135

  Fly   492 SILLAADGRVKLSDFGFCAQVSQEL--PKRKSLVGTPYWMSPEVISRLPYGPEVDIWSLGIMVIE 554
            ::|:..:|..|::|||....|..|:  |.|    |||.:|:||.......|.|.|||::|..|||
plant   136 NVLVGENGEAKIADFGCAKWVEPEITEPVR----GTPAFMAPEAARGERQGKESDIWAVGCTVIE 196

  Fly   555 MVDGEPPFFN---EPPLQAMRRIRDM-QPPNLKNAHKVSPRLQSFLDRMLVRDPAQRATAAELLA 615
            ||.|..|:..   ..|:..:.|:..: :.|.|..:  ::.:.:.||.:.|.::..:|.||::||.
plant   197 MVTGSQPWIGADFTDPVSVLYRVGYLGELPELPCS--LTEQAKDFLGKCLKKEATERWTASQLLN 259

  Fly   616 HPFLRQAGPPSLLVPLMRNA 635
            ||||... .|.|:..|:.|:
plant   260 HPFLVNK-EPELVTGLVTNS 278

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mbt	NP_523375.2	CRIB_PAK_like	9..54	CDD:238526
		STKc_PAK_II	360..620	CDD:270815	87/263 (33%)
		S_TKc	372..619	CDD:214567	86/262 (33%)
MAPKKK18	NP_172003.1	STKc_MAPKKK	2..263	CDD:270783	86/262 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910