DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mbt and NP1

DIOPT Version :9

Sequence 1:	NP_523375.2	Gene:	mbt / 32631	FlyBaseID:	FBgn0025743	Length:	639	Species:	Drosophila melanogaster
Sequence 2:	NP_563832.2	Gene:	NP1 / 837421	AraportID:	AT1G09000	Length:	666	Species:	Arabidopsis thaliana

Alignment Length:	273	Identity:	91/273 - (33%)
Similarity:	141/273 - (51%)	Gaps:	43/273 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   374 IGEGSTGTVCIATDKSTGRQVAVKKMDL--------RKQQRRELLFNEVVIMRDYHHPNIVETYS 430
            ||.|:.|||.:..:..:|..:|||::.:        :.|...:.|..||.::::..|||||....
plant    75 IGRGAFGTVYMGMNLDSGELLAVKQVLIAANFASKEKTQAHIQELEEEVKLLKNLSHPNIVRYLG 139

  Fly   431 SFLVNDELWVVMEYLEGGALTDIV-THSRMDEEQIATVCKQCLKALAYLHSQGVIHRDIKSDSIL 494
            :...:|.|.:::|::.||:::.:: ......|..:.|..:|.|..|.|||:..::|||||..:||
plant   140 TVREDDTLNILLEFVPGGSISSLLEKFGPFPESVVRTYTRQLLLGLEYLHNHAIMHRDIKGANIL 204

  Fly   495 LAADGRVKLSDFGFCAQVSQ--ELPKRKSLVGTPYWMSPEVISRLPYGPEVDIWSLGIMVIEMVD 557
            :...|.:||:|||...||::  .:...||:.||||||:||||.:..:....||||:|..|||||.
plant   205 VDNKGCIKLADFGASKQVAELATMTGAKSMKGTPYWMAPEVILQTGHSFSADIWSVGCTVIEMVT 269

  Fly   558 GEPP-----------FF-----NEPPLQAMRRIRDMQPPNLKNAHKVSPRLQSFLDRMLVRDPAQ 606
            |:.|           ||     :.||:          |..|.:..|      .||.:.|...|..
plant   270 GKAPWSQQYKEVAAIFFIGTTKSHPPI----------PDTLSSDAK------DFLLKCLQEVPNL 318

  Fly   607 RATAAELLAHPFL 619
            |.||:|||.|||:
plant   319 RPTASELLKHPFV 331

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mbt	NP_523375.2	CRIB_PAK_like	9..54	CDD:238526
		STKc_PAK_II	360..620	CDD:270815	91/273 (33%)
		S_TKc	372..619	CDD:214567	90/271 (33%)
NP1	NP_563832.2	STKc_MAPKKK	68..331	CDD:270783	90/271 (33%)
NP1	NP_563832.2	S_TKc	69..331	CDD:214567	90/271 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910