DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment mbt and CRK

DIOPT Version :9

Sequence 1:NP_523375.2 Gene:mbt / 32631 FlyBaseID:FBgn0025743 Length:639 Species:Drosophila melanogaster
Sequence 2:NP_001190048.1 Gene:CRK / 824217 AraportID:AT3G50530 Length:632 Species:Arabidopsis thaliana


Alignment Length:485 Identity:128/485 - (26%)
Similarity:196/485 - (40%) Gaps:91/485 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly   208 PLAVRTDQTNLQQYRSNLAPPSGGSMPQQQQTSPVGSVASGTRSNHSHTNNGNSGGSYPPMY--- 269
            |.:..:|||          |.....:|..:...|..|..:|.....:.|||......:.|.|   
plant     8 PNSSNSDQT----------PARNSPLPASESVKPSSSSVNGEDQCVTTTNNEGKKSPFFPFYSPS 62

  Fly   270 PTSHQQQQQQQQQAKQGGDQNQNP--LHPHAHPHPHHHQHLAKSASRASSSSGGASSAAQQASGA 332
            |..:...::...::......|..|  ......|.|...:|:....:|...|....|||..:.|.|
plant    63 PAHYFFSKKTPARSPATNSTNSTPKRFFKRPFPPPSPAKHIRAVLARRHGSVKPNSSAIPEGSEA 127

  Fly   333 SGGAAGQPKQDQRLTHEQFRAALQMVVSAGDPRENLDHFNKIGEGSTGTVCIATDK---STGRQV 394
            .||..|..|.      ..|..:.......||         ::|.|..|..|.|..|   :.|:||
plant   128 EGGGVGLDKS------FGFSKSFASKYELGD---------EVGRGHFGYTCAAKFKKGDNKGQQV 177

  Fly   395 AVKKMDLRKQQRR---ELLFNEVVIMRDYH-HPNIVETYSSFLVNDELWVVMEYLEGGALTDIVT 455
            |||.:...|....   |.:..||.|:|... |.|:...|.::..:|.:::|||..|||.|.|.:.
plant   178 AVKVIPKAKMTTAIAIEDVRREVKILRALSGHNNLPHFYDAYEDHDNVYIVMELCEGGELLDRIL 242

  Fly   456 H--SRMDEEQIATVCKQCLKALAYLHSQGVIHRDIKSDSILLAA---DGRVKLSDFG-------- 507
            .  .:..||...||..|.|..:|:.|.|||:|||:|.::.|..:   ..::|..|||        
plant   243 SRGGKYTEEDAKTVMIQILNVVAFCHLQGVVHRDLKPENFLFTSKEDTSQLKAIDFGLSDYVRPG 307

  Fly   508 -------FCAQVSQEL---------------PKRKSLVGTPYWMSPEVISRLPYGPEVDIWSLGI 550
                   .|....|.|               .:...:||:.|:::|||:.| .|..|.||||:|:
plant   308 KALRLYAICKLRFQNLETSICLYALTIAFADERLNDIVGSAYYVAPEVLHR-SYSTEADIWSVGV 371

  Fly   551 MVIEMVDGEPPFFNEPPLQAMRRIRDMQP-------PNLKNAHKVSPRLQSFLDRMLVRDPAQRA 608
            :|..::.|..||:........|.:....|       |.|      |...:.|:.|:|.:||.:|.
plant   372 IVYILLCGSRPFWARTESGIFRAVLKADPSFDDPPWPLL------SSEARDFVKRLLNKDPRKRL 430

  Fly   609 TAAELLAHPFLRQAG----PPSLLV-PLMR 633
            |||:.|:||:::.:.    |..:|| .|||
plant   431 TAAQALSHPWIKDSNDAKVPMDILVFKLMR 460

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
mbtNP_523375.2 CRIB_PAK_like 9..54 CDD:238526
STKc_PAK_II 360..620 CDD:270815 90/308 (29%)
S_TKc 372..619 CDD:214567 88/295 (30%)
CRKNP_001190048.1 STKc_CAMK 147..440 CDD:270687 89/308 (29%)
S_TKc 148..441 CDD:214567 90/308 (29%)
Glo_EDI_BRP_like 526..>597 CDD:301325
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
00.000

Return to query results.
Submit another query.