DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mbt and NP3

DIOPT Version :9

Sequence 1:	NP_523375.2	Gene:	mbt / 32631	FlyBaseID:	FBgn0025743	Length:	639	Species:	Drosophila melanogaster
Sequence 2:	NP_187254.1	Gene:	NP3 / 819774	AraportID:	AT3G06030	Length:	651	Species:	Arabidopsis thaliana

Alignment Length:	289	Identity:	92/289 - (31%)
Similarity:	146/289 - (50%)	Gaps:	45/289 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   374 IGEGSTGTVCIATDKSTGRQVAVKKMDL--------RKQQRRELLFNEVVIMRDYHHPNIVETYS 430
            ||.|:.|.|.:..:..:|..:|:|::.:        :.|.....|..||.::::..|||||....
plant    74 IGCGAFGRVYMGMNLDSGELLAIKQVLIAPSSASKEKTQGHIRELEEEVQLLKNLSHPNIVRYLG 138

  Fly   431 SFLVNDELWVVMEYLEGGALTDIV-THSRMDEEQIATVCKQCLKALAYLHSQGVIHRDIKSDSIL 494
            :...:|.|.::||::.||:::.:: ......|..|....||.|..|.|||:.|::|||||..:||
plant   139 TVRESDSLNILMEFVPGGSISSLLEKFGSFPEPVIIMYTKQLLLGLEYLHNNGIMHRDIKGANIL 203

  Fly   495 LAADGRVKLSDFGFCAQVSQ--ELPKRKSLVGTPYWMSPEVISRLPYGPEVDIWSLGIMVIEMVD 557
            :...|.::|:|||...:|.:  .:...||:.||||||:||||.:..:....||||:|..||||..
plant   204 VDNKGCIRLADFGASKKVVELATVNGAKSMKGTPYWMAPEVILQTGHSFSADIWSVGCTVIEMAT 268

  Fly   558 GEPPFFNE----------------PPLQAMRRIRDMQPPNLKNAHKVSPRLQSFLDRMLVRDPAQ 606
            |:||:..:                ||:          |.:|      ||..:.||.:.|.::|:.
plant   269 GKPPWSEQYQQFAAVLHIGRTKAHPPI----------PEDL------SPEAKDFLMKCLHKEPSL 317

  Fly   607 RATAAELLAHPFLRQAGPPSLLVPLMRNA 635
            |.:|.|||.|||:  .|......|..||:
plant   318 RLSATELLQHPFV--TGKRQEPYPAYRNS 344

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mbt	NP_523375.2	CRIB_PAK_like	9..54	CDD:238526
		STKc_PAK_II	360..620	CDD:270815	88/272 (32%)
		S_TKc	372..619	CDD:214567	87/271 (32%)
NP3	NP_187254.1	STKc_MAPKKK	67..330	CDD:270783	87/271 (32%)
NP3	NP_187254.1	S_TKc	68..330	CDD:214567	87/271 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910