DRSC/TRiP Functional Genomics Resources

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Protein Alignment mbt and Strada

DIOPT Version :10

Sequence 1:NP_523375.2 Gene:mbt / 32631 FlyBaseID:FBgn0025743 Length:639 Species:Drosophila melanogaster
Sequence 2:NP_001239377.1 Gene:Strada / 72149 MGIID:1919399 Length:431 Species:Mus musculus


Alignment Length:372 Identity:104/372 - (27%)
Similarity:165/372 - (44%) Gaps:86/372 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly   339 QPKQDQRLTHEQFRAALQMVVSAGDPRENLDHF----------NKIGEG--STGTVCIATDKSTG 391
            ||..|.|  .:...|:.:.:.|...| |.:..|          ..||:|  ...||.:|..|.||
Mouse    33 QPPGDTR--RKANEASSESIASFSKP-EMMSSFLPEGGCYELLTIIGKGFEDLMTVNLARYKPTG 94

  Fly   392 RQVAVKKMDLRKQQRRELLF--NEVVIMRDYHHPNIVETYSSFLVNDELWVVMEYLEGGALTDIV 454
            ..|.|::::|.......:.|  .|:.:.:.:.|||||...::|:.::|||||..::..|:..|::
Mouse    95 EYVTVRRINLEACSNEMVTFLQGELHVSKLFSHPNIVPYRATFIADNELWVVTSFMAYGSAKDLI 159

  Fly   455 -TH--SRMDEEQIATVCKQCLKALAYLHSQGVIHRDIKSDSILLAADGRVKLSDFGFCAQVS--- 513
             ||  ..|:|..||.:.:..||||.|:|..|.:||.:|:..||::.||:|.||  |..:.:|   
Mouse   160 GTHFMDGMNELAIAYILQGVLKALDYIHHMGYVHRSVKASHILISTDGKVYLS--GLRSNLSMIS 222

  Fly   514 --------QELPKRKSLVGTPYWMSPEVISR--LPYGPEVDIWSLGIMVIEMVDGEPPFFNEPPL 568
                    .:.|| .|:...| |:||||:.:  ..|..:.||:|:||...|:.:|..||.:.|..
Mouse   223 HGQRQRAVHDFPK-YSIKVLP-WLSPEVLQQNLQGYDAKSDIYSVGITACELANGHVPFKDMPAT 285

  Fly   569 Q------------------------AMRRIRDMQPPNLKNA------------------HKV-SP 590
            |                        .|...|.:..|.|.::                  |:. ||
Mouse   286 QMLLEKLNGTVPCLLDTSTIPAEELTMSPSRSIANPGLNDSLAAGSLRPSNGDSPSHPYHRTFSP 350

  Fly   591 RLQSFLDRMLVRDPAQRATAAELLAHPFLRQ------AGPPSLLVPL 631
            ...:|:::.|.|:|..|..|:.||.|.|.:|      ...|.||.|:
Mouse   351 HFHNFVEQCLQRNPDARPNASTLLNHSFFKQIKRRASEALPELLRPV 397

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
mbtNP_523375.2 CRIB_PAK_like 9..54 CDD:238526
STKc_PAK_II 360..620 CDD:270815 94/332 (28%)
StradaNP_001239377.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 32..52 5/20 (25%)
PK_STRAD_alpha 70..396 CDD:173767 94/329 (29%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 314..344 3/29 (10%)
Blue background indicates that the domain is not in the aligned region.

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