Protein Alignment mbt and STK3

DIOPT Version :9

• Sequence 1: NP_523375.2
• Gene: mbt / 32631
• FlyBaseID: FBgn0025743
• Length: 639
• Species: Drosophila melanogaster
• Sequence 2: XP_016869245.1
• Gene: STK3 / 6788
• HGNCID: 11406
• Length: 580
• Species: Homo sapiens
• Alignment Length: 325
• Identity: 122/325 - (37%)
• Similarity: 185/325 - (56%)
• Gaps: 18/325 - (5%)

  Fly   321 GASSAAQQASGASGGAAGQPKQDQRLTHEQFRAALQMVVSAGDPRENLDHFNKIGEGSTGTVCIA 385
            ||:|..::...::.|.  :.|||.:|      ..|........|.|..|...|:||||.|:|..|
Human    73 GAASVFKKKEWSTQGE--ENKQDSKL------KKLSEDSLTKQPEEVFDVLEKLGEGSYGSVFKA 129

  Fly   386 TDKSTGRQVAVKKMDLRKQQRRELLFNEVVIMRDYHHPNIVETYSSFLVNDELWVVMEYLEGGAL 450
            ..|.:|:.||:|::.:....:.  :..|:.||:....|.:|:.|.|:..|.:||:||||...|::
Human   130 IHKESGQVVAIKQVPVESDLQE--IIKEISIMQQCDSPYVVKYYGSYFKNTDLWIVMEYCGAGSV 192

  Fly   451 TDIV--THSRMDEEQIATVCKQCLKALAYLHSQGVIHRDIKSDSILLAADGRVKLSDFGFCAQVS 513
            :||:  .:..:.|::|||:.|..||.|.|||....||||||:.:|||..:|..||:|||...|::
Human   193 SDIIRLRNKTLIEDEIATILKSTLKGLEYLHFMRKIHRDIKAGNILLNTEGHAKLADFGVAGQLT 257

  Fly   514 QELPKRKSLVGTPYWMSPEVISRLPYGPEVDIWSLGIMVIEMVDGEPPFFNEPPLQAMRRIRDMQ 578
            ..:.||.:::|||:||:||||..:.|....|||||||..|||.:|:||:.:..|::|:..|....
Human   258 DTMAKRNTVIGTPFWMAPEVIQEIGYNCVADIWSLGITSIEMAEGKPPYADIHPMRAIFMIPTNP 322

  Fly   579 PPNLKNAHKVSPRLQSFLDRMLVRDPAQRATAAELLAHPFLRQAGPPSLLVPLMRNA------RH 637
            ||..:.....|.....|:.:.||::|.|||||.:||.|||::.|.|.|:|..|:..|      ||
Human   323 PPTFRKPELWSDDFTDFVKKCLVKNPEQRATATQLLQHPFIKNAKPVSILRDLITEAMEIKAKRH 387

  Fly   638  637
            Human   388  387

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mbt	NP_523375.2	CRIB_PAK_like	9..54	CDD:238526
		STKc_PAK_II	360..620	CDD:270815	105/261 (40%)
		S_TKc	372..619	CDD:214567	101/248 (41%)
STK3	XP_016869245.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910